Cyclization of geranylgeranyl diphosphate to taxa-4(5),11(12)-diene is the committed step of taxol biosynthesis in Pacific yew

Journal of Biological Chemistry

Volumn 270, Issue 15, 1995, Pages 8686-8690

  Koepp, Alfred E ^a   Hezari, Mehri ^a   Zajicek, Jaroslav ^a   Vogel, Brigitte Stofer ^a   LaFever, Roy E ^a   Lewis, Norman G ^a   Croteau, Rodney ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DITERPENE; FARNESYL TRANS TRANSFERASE; PACLITAXEL; TAXANE DERIVATIVE;

ARTICLE; CANCER CHEMOTHERAPY; CYCLIZATION; DRUG SYNTHESIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; OXYGENATION; PRIORITY JOURNAL;

ALKENES; DITERPENES; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; PACLITAXEL; POLYISOPRENYL PHOSPHATES; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TREES;

OXY; TAXUS; TAXUS BREVIFOLIA;

EID: 0028964563     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.270.15.8686     Document Type: Article

References (42)