The median paralysis unit: A more pharmacologically relevant unit of biologic activity for botulinum toxin

Toxicon

Volumn 33, Issue 2, 1995, Pages 217-227

  Pearce, L Bruce ^a   Borodic, Gary E ^b   Johnson, Eric A ^c   First, Eric R ^a   Maccallum, Robert ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BOTULINUM TOXIN; BOTULINUM TOXIN A;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG FORMULATION; DRUG POTENCY; INTRAMUSCULAR DRUG ADMINISTRATION; MALE; MOUSE; NONHUMAN; PARALYSIS; PRIORITY JOURNAL;

ANIMAL; BOTULINUM TOXINS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MICE; MICE, INBRED STRAINS; PARALYSIS; SUPPORT, NON-U.S. GOV'T; SYMPATHECTOMY, CHEMICAL; WEIGHTS AND MEASURES;

ANIMALIA;

EID: 0028964514     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/0041-0101(94)00137-W     Document Type: Article

References (33)

1. Reorganization of intrinsic components in the distal motor axon during outgrowth
2. Botulinum induced alteration of nerve muscle interactions in human orbicularis oculi following treatment for blepharospasm
3. The determination of the dosage-mortality curve from small numbers
4. A toxin for the treatment of spasmodic torticollis. Dysphagia and regional toxin spread
5. Clinical and scientific aspects of botulinum A toxin
6. Therapeutic botulinum toxin: histologic effects and diffusion properties
7. Botulinum B toxin as an alternative to botulinum A toxin: a histologic study
8. Pharmacology and histology of the therapeutic application of botulinum toxin
9. Botulinum toxin: dangerous terminology errors
10. Therapeutic potential of botulinum toxin in neurological disorders
11. The effects of botulinum toxin on the pattern of innervation of skeletal muscle in the mouse
12. The effects of implantation of an extra nerve on axonal sprouting usually induced by botulinum toxin in skeletal muscle of the mouse
13. Use of botulinum type F injections to treat torticollis in patients with immunity to botulinum toxin type A
14. Clostridial neurotoxins and the central nervous system: functional studies on isolated preparations
15. Clostridium botulinum toxins: a general review of involvement in disease, structure, mode of action and preparation for clinical use
16. Terminal nerve and motor end plate changes in human orbicularis muscle following botulinum A toxin injection
17. Therapeutic uses of botulinum toxin
18. Botulinum toxin: dangerous terminology errors (Response)
19. Rapid in vivo assay method for type G botulinal toxin
20. Assays for botulinum and tetanus toxins
21. Measurement of botulinum toxin activity
22. Dose standardisation of botulinum toxin
23. Properties and use of botulinum toxin and other microbiological neurotoxins in medicine
24. Microbiological methods: standardized assay for clostridium botulinum toxins
25. Botulinum toxin production and immunology
26. Different effects of types A and B botulinum toxin on transmitter release at the rat neuromuscular junction
27. The origin, structure, and pharmacological activity of botulinum toxin
28. Detection of clostridium botulinum toxin by local paralysis elicited with intramuscular challenge
29. The error determination of toxicity
30. The pharmacology of botulinum toxin
31. Botulinum antibodies in dystonic patients treated with type A botulinum toxin: frequency and significance