Coexpression of trk family members and low-affinity neurotrophin receptors in rat dorsal root ganglion neurons

Molecular Brain Research

Volumn 30, Issue 1, 1995, Pages 158-164

  Kashiba, Hitoshi ^a   Noguchi, Koichi ^b   Ueda, Yoshihiro ^a   Senba, Emiko ^b  

^a Kansai College of Oriental Medicine   (Japan)

^b WAKAYAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

Co expression; Dorsal root ganglion neuron; In situ hybridization; Low affinity neurotrophin receptor; Rat; trk receptor

Indexed keywords

GROWTH FACTOR RECEPTOR; MESSENGER RNA; NEUROTROPHIN; PROTEIN TYROSINE KINASE;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CELL SUBPOPULATION; CONTROLLED STUDY; HISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MULTIGENE FAMILY; NERVE CELL; NEUROCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; PROTO ONCOGENE; RAT; SPINAL GANGLION;

ANIMAL; CYCLIC AMP-DEPENDENT PROTEIN KINASES; GANGLIA, SPINAL; GENE EXPRESSION; IN SITU HYBRIDIZATION; MALE; NEURONS; PROTEIN KINASE C; PROTEIN-TYROSINE KINASE; RATS; RATS, WISTAR; RNA, MESSENGER; SUPPORT, NON-U.S. GOV'T;

ANIMALIA;

EID: 0028962508     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0169-328X(94)00249-E     Document Type: Article

References (24)

1. Differential expression of nerve growth factor receptors leads to altered binding affinity and neurotrophin responsiveness
2. The low-affinity p75 nerve growth factor (NGF) receptor mediates NGF-induced tyrosine phosphorylation
3. Neurotrophin-5: novel neurotrophic factor that activates trk and trkB
4. Dorsal root ganglion neurons expressing trk are selectively sensitive to NGF deprivation in utero
5. Neurotrophin receptors: a window into neuronal differentiation
6. p75-deficient trigeminal sensory neurons have an altered response to NGF but not to other neurotrophins
7. The neurotrophins BDNF, NT-3, and NGF display distinct patterns of retrograde axonal transport in peripheral and central neurons
8. Evolutionary studies of the nerve growth factor family reveal a novel member abundantly expressed in Xenopus ovary
9. High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor
10. Nerve growth factor mediates signal transduction through trk homodimer receptors
11. Tyrosine phosphorylation and tyrosine kinase activity of the trk protooncogene product induced by NGF
12. trkB, a novel tyrosine protein kinase receptor expressed during mouse neural development
13. The trk proto-oncogene encodes a receptor for nerve growth factor
14. trkC, a new member of the trk family of tyrosine protein kinase, is a receptor for neurotrophin-3
15. Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system
16. Expression and coexpression of Trk receptors in subpopulations of adult primary sensory neurons projecting to identified peripheral targets
17. The rat trk protooncogene product exhibits properties characteristic of the slow nerve growth factor receptor
18. The nerve growth factor family of receptors
19. Neurotrophin receptor genes are expressed in distinct patterns in developing dorsal root ganglia
20. Gene transfer and molecular cloning of the rat nerve growth factor receptor
21. Binding of brain-derived neurotrophic factor to the nerve growth factor receptor
22. Binding of neurotrophin-3 to its neuronal receptors and interactions with nerve growth factor and brain-derived neurotrophic factor
23. Colocalization of NGF binding sites, trk mRNA, and low-affinity NGF receptor mRNA in primary sensory neurons: responses to injury and infusion of NGF
24. trk) and low-affinity nerve growth factor receptor (LNGFR) in the adult and aged human peripheral nervous system