The genetics of cell cycle checkpoints

Current Opinion in Genetics and Development

Volumn 5, Issue 1, 1995, Pages 5-11

  Murray, Andrew W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN KINASE;

CELL CYCLE; CELL REGENERATION; CYTOGENETICS; FUNGAL GENETICS; GENETIC DAMAGE; MITOSIS; NONHUMAN; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; YEAST;

ANIMAL; CELL CYCLE; SCHIZOSACCHAROMYCES; VERTEBRATES;

EID: 0028962292     PISSN: 0959437X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-437X(95)90046-2     Document Type: Article

References (64)

1. Checkpoints: controls that ensure the order of cell cycle events
2. Creative blocks: cell cycle checkpoints and feedback controls
3. 2 checkpoints-fission yeast as a model system
4. The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae
5. Feedback control of mitosis in budding yeast
6. S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function
7. Fission yeast genes involved in coupling mitosis to DNA replication
8. 2 checkpoint pathways in S. pombe
9. Checkpoint controls in Schizosaccharomyces pombe: radl
10. Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair
11. Cell cycle checkpoints
12. 1 arrest defines a second checkpoint for damaged DNA in the cell cycle of Saccharomyces cerevisiae
13. 1 checkpoint control in the yeast Saccharomyces cerevisiae following exposure to DNA-damaging agents
14. WAF1, a potential mediator of p53 tumor suppression
15. WAF1/CIP1 is induced in p53-mediated Gl arrest and apoptosis
16. Loss of a yeast telomere: arrest, recovery, and chromosome loss
17. Lethality induced by a single site-specific double-strand break in a dispensable yeast plasmid
18. Thymocyte apoptosis induced by p53-dependent and independent pathways
19. p53 is required for radiation-induced apoptosis in mouse thymocytes
20. The SAD1/RAD53 protein kinase controls multiple checkpoints and DNA damage-induced transcription in yeast
21. SPK1 is an essential S-phase-specific gene of Saccharomyces cerevisiae that encodes a nuclear serine/threonine/tyrosine kinase
22. The assembly of signalling complexes by receptor tyrosine kinases
23. Mutation of fission yeast cell cycle control genes abolishes dependence of mitosis on DNA replication
24. cdc2
25. Human weel maintains mitotic timing by protecting the nucleus from cytoplasmically activated Cdc2 kinase
26. cdc28
27. CDC28 tyrosine phosphorylation is not required for entry into mitosis in S. cerevisiae
28. The Saccharomyces cerevisiae checkpoint gene BUB1 encodes a novel protein kinase
29. MPS1 and MPS2: novel yeast genes defining distinct steps of spindle pole body duplication
30. Centromere mutations induce a mitotic delay in S. cerevisiae
31. The Saccharomyces cerevisiae cell cycle
32. 1+ gene
33. +
34. 18+ gene product couples S phase to START and mitosis
35. Identification and characterization of new elements involved in checkpoint and feedback controls in fission yeast
36. Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2
37. Fission yeast weel protein kinase is not required for DNA damage-dependent mitotic arrest
38. Universal control mechanism regulating cell cycle timing of M-phase
39. 14-3-3 protein homologs required for the DNA damage checkpoint in fission yeast
40. 14-3-3 proteins: a highly conserved widespread family of eukaryotic proteins
41. Stimulatory effects of yeast and mammalian 14-3-3 proteins on the Raf protein kinase
42. Binding of 14-3-3 proteins to the protein kinase Raf and effects on its activation
43. MAP-kinase dependent mitotic feedback arrest in Xenopus egg extracts
44. Premature chromosome condensation in a is DNA-mutant of BHK cells
45. The RCC1 protein, a regulator of chromosome condensation locates in the nucleus and binds DNA
46. Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1
47. RCC1, a regulator of mitosis, is essential for DNA replication
48. Evidence for a dual role for TC4 protein in regulating nuclear structure and cell cycle progression
49. Mutation of the hamster cell cycle gene RCC1 is complemented by the homologous genes of Drosophila and S. cerevisiae
50. A yeast mutant, PRP20, altered in mRNA metabolism and maintenance of the nuclear structure, is defective in a gene homologous to the human gene RCC1 which is involved in the control of chromosome condensation
51. Yeast pheromone response pathway: characterization of a suppressor that restores mating to receptorless mutants
52. Premature initiation of mitosis in yeast lacking RCC1 or an interacting GTPase
53. A fission yeast RCC1-related protein is required for the mitosis to interphase transition
54. The GTP-binding protein Ran/TC4 is required for protein import into the nucleus
55. Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor
56. Cell cycle arrest of cdc mutants and specificity of the RAD9 checkpoint
57. The REC1 gene of Ustilago maydis involved in the cellular response to DNA damage encodes an exonuclease
58. + gene of Schizosaccharomyces pombe is involved in multiple check point functions and in DNA repair
59. Cloning and characterization of the rad4 gene of Schizosaccharomyces pombe, a gene showing short regions of sequence similarity to the human XRCC1 gene
60. The S. pombe hus5 gene encodes a ubiquitin conjugating enzyme required for normal mitosis
61. Coupling M phase and S phase: controls maintaining the dependence of mitosis on chromosome replication
62. mik1 and wee1 cooperate in the inhibitory tyrosine phosphorylation of cdc2
63. The S. pombe cdc16 gene is required both for maintenance of p34cdc2 kinase activity and regulation of septum formation: a link between mitosis and cytokinesis?