HLA‐B27 subtypes in Asian patients with ankylosing spondylitis Evidence for new associations

Tissue Antigens

Volumn 45, Issue 3, 1995, Pages 169-176

  Lopez Larrea C ^a,c   Sujirachato, K ^b   Mehra, N K ^d   Chiewsilp, P ^b   Isarangkura, D ^b   Kanga, U ^d   Dominguez, O ^a   Coto, E ^a   Pena M ^a   Setien F ^c   Gonzalez Roces S ^a  

^a HOSPITAL UNIVERSITARIO CENTRAL DE ASTURIAS   (Spain)

^b MAHIDOL UNIVERSITY   (Thailand)

^c UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^d ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

ankylosing spondylitis; HLA B27 subtype

Indexed keywords

HLA B27 ANTIGEN;

ANKYLOSING SPONDYLITIS; ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; ETHNIC DIFFERENCE; ETHNIC GROUP; EXON; GENETIC POLYMORPHISM; HLA SYSTEM; HUMAN; INDIAN; MAJOR CLINICAL STUDY; OLIGONUCLEOTIDE PROBE; PATHOGENESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; BASE SEQUENCE; CASE-CONTROL STUDIES; COMPARATIVE STUDY; DNA; DNA PROBES, HLA; GENE FREQUENCY; GENES, MHC CLASS I; HLA-B27 ANTIGEN; HUMAN; INDIA; MOLECULAR SEQUENCE DATA; POINT MUTATION; POLYMERASE CHAIN REACTION; PROTEIN CONFORMATION; SPONDYLITIS, ANKYLOSING; SUPPORT, NON-U.S. GOV'T; THAILAND;

EID: 0028960650     PISSN: 00012815     EISSN: 13990039     Source Type: Journal    
DOI: 10.1111/j.1399-0039.1995.tb02436.x     Document Type: Article

References (38)

1. Ankylosing spondylitis and HLA‐B27
2. High association of HLA antigen W27 with ankylosing spondylitis
3. Subtypes of HLA‐B27 detected by cytotoxic T lymphocytes and their role in self recognition
4. Six variants of HLA‐B27 identified by isoelectric‐focusing
5. Molecular analysis of the variant alloantigen HLA‐B27d (B*2703) identifies a unique single amino acid substitution
6. A novel HLA‐B27 allele maps B27 allospecificity to the region around position 70 in the alpha 1 domain
7. HLA‐B27 and HLA‐A2 subtypes: structure, evolution and function
8. Nucleotide sequence of HLA ‐B*2706
9. Structure and diversity of HLA‐B27 specific T cell epitopes. Analysis with site‐directed mutants mimicking HLA‐B27 subtype polymorphism
10. Changes in the repertoire of peptides bound to HLA‐B27 subtypes and to site‐specific mutants inside and outside pocket B
11. Distribution of HLA‐B27 subtypes in patients with ankylosing spondylitis: the disease is associated with a common determinant of the various B27 molecules
12. Immunogenetic basis of the seronegative spondyloarthropathies
13. HLA class I typing by PCR: HLA‐B27 and an African B27 subtype
14. The HLA‐B7Qui antigen is encoded by a new subtype of HLA‐B27 (B*2708)
15. 2m: an animal model of HLA‐B27‐associated human disorders
16. The HLA‐B27 antigen family and disease susceptibility. In molecular mimicry in HLA‐B27 related arthritis
17. HLA‐B27 subtypes: implications for the spondyloarthropathies
18. HLA‐B27‐restricted CD8 T cells derived from synovial fluids of patients with reactive arthritis and ankylosing spondylitis
19. Anchoring pockets in human histocompatibility complex leukocyte antigen (HLA) class I molecules: analysis of the conserved B″45″ pocket of HLA‐B27
20. The European Spondyloarthropathy study group preliminary criteria for the classification of spondyloarthropathy
21. On estimating the relation between blood group and disease
22. Measures of potential impact and summary of the measures
23. Molecular typing of HLA‐B27 alleles
24. Clonal analysis of alloreactive T cell responses against the closely related B*2705 and B*2703 subtypes
25. Guilt by association: HLA‐B27 and ankylosing spondylitis
26. The three‐dimensional structure of HLA‐B27 at 2.1 A resolution suggests a general mechanism for tight peptide binding to MHC
27. Identification of self peptides bound to purified HLA‐B27
28. HLA class I binding of synthetic nonamer peptides carrying major anchor residue motifs of HLA‐B27 (B*2705)‐binding peptides
29. Dominant aromatic/aliphatic C‐terminal anchor in HLA‐B*2702 and B*2705 peptide motifs
30. The peptide binding specificity of HLA‐B27 subtypes
31. The role of binding pockets for amino‐terminal peptide residues in HLA‐B27 allorecognition
32. Refined structure of the human histocompatibility antigen HLA‐A2 at 2.6 A resolution
33. Allele‐specific motifs revealed by sequencing of self‐peptides eluted from MHC molecules
34. Prominent role of secondary anchor residues in peptide binding to HLA‐A2.1 molecules
35. Characteristics of endogenous peptides eluted from the class I MHC molecule HLA‐B7 determined by mass spectrometry and computer modeling
36. Different HLA‐B27 subtypes present the same immunodominant Epstein‐Barr virus peptide