The structural basis of specific base-excision repair by uracil–DNA glycosylase

Nature

Volumn 373, Issue 6514, 1995, Pages 487-493

  Savva, Renos ^a   Mc Auley Hecht, Katherine ^b   Brown, Tom ^b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; DNA GLYCOSYLTRANSFERASE; DOUBLE STRANDED DNA; SINGLE STRANDED DNA; TRINUCLEOTIDE; URACIL;

ARTICLE; BINDING SITE; CATALYSIS; CRYSTAL STRUCTURE; DNA BINDING; EXCISION REPAIR; HERPES SIMPLEX VIRUS 1; HYDROLYSIS; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING;

AMINO ACID SEQUENCE; BINDING SITES; CATALYSIS; COMPUTER GRAPHICS; CRYSTALLOGRAPHY, X-RAY; DNA REPAIR; HERPESVIRUS 1, HUMAN; HUMAN; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; N-GLYCOSYL HYDROLASES; PROTEIN STRUCTURE, SECONDARY; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; SUPPORT, NON-U.S. GOV'T; THYMINE; URACIL;

EID: 0028959237     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/373487a0     Document Type: Article

References (41)

1. Lindahl, T. Proc. natn. Acad. Sei. U.S.A. 71, 3649-3653 (1974).
2. Kaboev, O. K., Luchinka, L. A. & Kuziakina, T. I. J. Bact. 164, 421-424 (1985).
3. Crosby, B., Prakash, L., Davis, H. & Hinkie, D. C. Nucleic Acids Res. 9, 5797-5809 (1981).
4. Olsen, L. C., Aasland, R., Wittwer, C. U., Krokan, H. E. & Heiland, D. E. EMBO J. 9, 3121-3125 (1989).
5. Upton, C., Stuart, D. T. & McFadden, G. Proc. natn. Acad. Sei. U.S.A. 90, 4518-4522 (1993).
6. Mullaney, J., Moss, H. W. Mc L. & McGeogh, D. J. J. gen. Virol. 70, 449-454 (1989).
7. Caradonna, S., Worrad, D. & Lirette, R. J. Virol. 61, 3040-3047 (1987).
8. Baer, R. et al. Nature 310, 207-211 (1984).
9. Davison, A. J. & Scott, J. E. J. gen. Virol. 67, 1759-1816 (1986).
10. Cone, R., Duncan, J., Hamilton, L. & Friedberg, E. C. Biochemistry 16, 3194-3201 (1977).
11. Lindahl, T., Ljungquist, S., Siegert, W, Nyberg, B. & Sperens, B. J. biol. Chem. 252, 3286-3294 (1977).
12. Dianov, G. et al. Nucleic Acids Res. 22, 993-998 (1994).
13. Lindahl, T. Prog. Nucleic Acid Res. molec. Biol. 22, 135-192 (1979).
14. Mosbaugh, D. W. Rev. biochem. Tox. 9, 69-130 (1988)
15. Verri, A., Mazzarello, P., Biamonti, G., Spadari, S. & Focher, F. Nucleic Acids Res. 18, 5775-5780 (1990).
16. Focher, F., Verri, A., Verzeietti, S., Mazzarello, P. & Spadari, S, Chromosoma. Berl. 102 (Suppl.), S67-S71 (1992).
17. Slupphaug, G. et al. Nucleic Acids Res. 21, 2579-2584 (1993).
18. Mauro, D. J., De Reil, J. K., Tailarida, R. J. & Sirover, M. A. Molec. Pharmac. 43, 854-857 (1993).
19. Hatahet, Z., Kow, Y. W., Purmal, A. A., Cunningham, R. P. & Wallace, S. S. J. biol. Chem. 269, 18814-18820 (1994).
20. Eftedal, I., Guddal, P. H. Slupphaug, G., Volden, G. & Krokan, H. E. Nucleic Acids Res. 21, 2095-2101 (1993).
21. Cone, R., Duncan, J., Hamilton, L. & Friedberg, E. C. Biochemistry 16, 3194-3201 (1977).
22. Lindahl, T., Ljungquist, S., Siegert, W., Nyberg, B. & Sperens, B. J. biol. Chem. 252, 3286-3294 (1977).
23. Krokan, H. & Wittwer, C. U. Nucleic Acids Res. 9, 2599-2613 (1981).
24. Pyles, R. B. & Thompson, R. L. J. Virol. 68, 4963-1972 (1994).
25. Savva, R. & Pearl, L. H. J. molec. Biol. 234, 910-912 (1993).
26. Rossman, M. G. et al. in The Enzymes Vol. 11 (ed. Boyer, P. D.) 61-102 (Academic, New York, 1975).
27. Klimasaukas, S., Kumar, S., Roberts, R. J. & Cheng, X. Cell 76, 357-369 (1994).
28. Bennet, S. E., Jensen, O. N., Barofsky, D. F. & Mosbaugh, D, W. J. biol. Chem. 269, 21870-21879 (1994).
29. Krokan, H. E. et al. Proc. N.Y. Acad. Sei. (Abstr.) (July 31-Aug. 4, Burlington, VT, 1993).
30. Varshney, U. & van de Sande, J. H. Biochemistry 30, 4055-4061 (1991).
31. Leslie, A, G. W. MOSFLM Users Guide (MRC-LMB, Cambridge, 1994).
32. Pflugrath, J. W. & Messerschmidt, A. Munich Area Detector New EEC System (1992).
33. Collaborative Computational Project No. 4. Acta crystaliogr. D50, 760-763 (1994).
34. Otwinowski, Z. in Isomorphous Replacement and Anomalous Scattering: Proceedings of the CCP4 Study Weekend 23-38 (SERC Daresbury Laboratory, 1991).
35. Jones, T. A., Zou, J.-Y., Cowan, S. W. & Kjeldgaard, M. Acta crystallogr. A47, 110-119 (1991).
36. Kleywegt, G. J. & Jones, T. A. in From First Map to Final Model: Proceedings of the CCP4 Study Weekend (eds Bailey, S. et al.) 59-66 (SERC Daresbury Laboratory, 1994).
37. Read, R. J. Acta crystallogr. A42, 140-149 (1986).
38. Brunger, A. T. X-PLOR Version 3.1. A System for X-Ray Crystallography and NMR (Yale Univ. Press, New Haven, CT, 1992).
39. Laskowski, R. J., MacArthur, M. W., Moss, D. S. & Thornton, J. M. J. Appl. crystallogr. 26, 283-290 (1993).
40. Kraulis, P. J. J. Appl. Crystallogr. 24, 946-950 (1991).
41. Flores, T., Moss, D. S. & Thornton, J. M. Protein Engng 7, 31-37 (1994)