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Volumn 85, Issue 3, 1995, Pages 607-614

Inherited thrombophilia: Resistance to activated protein C as a pathogenic factor of venous thromboembolism

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT PROTEIN; BLOOD CLOTTING FACTOR 5A; BLOOD CLOTTING FACTOR 8A; PROTEIN C; PROTEIN S; THROMBOMODULIN;

EID: 0028959158     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v85.3.607.bloodjournal853607     Document Type: Review
Times cited : (323)

References (93)
  • 1
    • 0002596183 scopus 로고
    • Epidemiology of pulmonary embolism and deep vein thrombosis
    • Bloom AL, Forbes CD, Thomas DP, Tuddenhamm EGD (eds): Edinburgh, UK, Churchill Livinstone
    • Goldhaber SZ: Epidemiology of pulmonary embolism and deep vein thrombosis, in Bloom AL, Forbes CD, Thomas DP, Tuddenhamm EGD (eds): Haemostasis and Thrombosis. Edinburgh, UK, Churchill Livinstone, 1994, p 1327
    • (1994) Haemostasis and Thrombosis , pp. 1327
    • Goldhaber, S.Z.1
  • 2
    • 0000549495 scopus 로고
    • Pathogenesis of venous thrombosis
    • Bloom AL, Forbes CD, Thomas DP, Tuddenham EGD (eds): Edinburgh, UK, Churchill Livingstone
    • Thomas DP: Pathogenesis of venous thrombosis, in Bloom AL, Forbes CD, Thomas DP, Tuddenham EGD (eds): Haemostasis and Thrombosis. Edinburgh, UK, Churchill Livingstone, 1994, p 1335
    • (1994) Haemostasis and Thrombosis , pp. 1335
    • Thomas, D.P.1
  • 3
    • 0002350130 scopus 로고
    • Familial venous thrombophilia
    • Bloom AL, Forbes CD, Thomas DP, Tuddenham EGD (eds): Edinburgh, UK, Churchill Livingstone
    • Allaart CF, Briët E: Familial venous thrombophilia, in Bloom AL, Forbes CD, Thomas DP, Tuddenham EGD (eds): Haemostasis and Thrombosis. Edinburgh, UK, Churchill Livingstone, 1994, p 1349
    • (1994) Haemostasis and Thrombosis , pp. 1349
    • Allaart, C.F.1    Briët, E.2
  • 4
    • 0026695880 scopus 로고
    • Thromboembolic disease - Critical evaluation of laboratory investigation
    • Malm J, Laurell M, Nilsson IM, Dahlbäck B: Thromboembolic disease - Critical evaluation of laboratory investigation. Thromb Haemost 68:7, 1992
    • (1992) Thromb Haemost , vol.68 , pp. 7
    • Malm, J.1    Laurell, M.2    Nilsson, I.M.3    Dahlbäck, B.4
  • 5
    • 0025241268 scopus 로고
    • Deficiencies of coagulation-inhibiting and fibrinolytic proteins in outpatients with deep-vein thrombosis
    • Heijboer H, Brandjes D, Büller HR, Sturk A, ten Cate JW: Deficiencies of coagulation-inhibiting and fibrinolytic proteins in outpatients with deep-vein thrombosis. N Engl J Med 323:1512, 1990
    • (1990) N Engl J Med , vol.323 , pp. 1512
    • Heijboer, H.1    Brandjes, D.2    Büller, H.R.3    Sturk, A.4    Ten Cate, J.W.5
  • 7
  • 8
    • 0027446268 scopus 로고
    • Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: Prediction of a cofactor to activated protein C
    • Dahlbäck B, Carlsson M, Svensson PJ: Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: Prediction of a cofactor to activated protein C. Proc Natl Acad Sci USA 90:1004, 1993
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 1004
    • Dahlbäck, B.1    Carlsson, M.2    Svensson, P.J.3
  • 11
    • 0028291210 scopus 로고
    • Linkage between inherited resistance to activated protein C and factor V gene mutation in venous thrombosis
    • Zöller B, Dahlbäck B: Linkage between inherited resistance to activated protein C and factor V gene mutation in venous thrombosis. Lancet 343:1536, 1994
    • (1994) Lancet , vol.343 , pp. 1536
    • Zöller, B.1    Dahlbäck, B.2
  • 13
    • 0028305045 scopus 로고
    • Blood coagulation factor Va abnormality associated with resistance to activated protein C in venous thrombophilia
    • Sun X, Evatt B, Griffin JH: Blood coagulation factor Va abnormality associated with resistance to activated protein C in venous thrombophilia. Blood 83:3120, 1994
    • (1994) Blood , vol.83 , pp. 3120
    • Sun, X.1    Evatt, B.2    Griffin, J.H.3
  • 14
    • 0028098210 scopus 로고
    • Resistance to activated protein C as a basis for venous thrombosis
    • Svensson PJ, Dahlbäck B: Resistance to activated protein C as a basis for venous thrombosis. N Engl J Med 330:517, 1994
    • (1994) N Engl J Med , vol.330 , pp. 517
    • Svensson, P.J.1    Dahlbäck, B.2
  • 16
    • 0026025457 scopus 로고
    • Role of antithrombin III as a regulator of in vivo coagulation
    • Bauer KA, Rosenberg RD: Role of antithrombin III as a regulator of in vivo coagulation. Semin Hematol 28:10, 1991
    • (1991) Semin Hematol , vol.28 , pp. 10
    • Bauer, K.A.1    Rosenberg, R.D.2
  • 17
    • 0002425830 scopus 로고
    • Regulation of blood coagulation by protease inhibitors
    • Stamatoyannopoulos G, Nienhuis AW, Majerus PW, Varmus H (eds): Philadelphia, PA, Saunders
    • Broze GJ Jr, Tollefsen DM: Regulation of blood coagulation by protease inhibitors, in Stamatoyannopoulos G, Nienhuis AW, Majerus PW, Varmus H (eds): The Molecular Basis of Blood Diseases. Philadelphia, PA, Saunders, 1994, p 629
    • (1994) The Molecular Basis of Blood Diseases , pp. 629
    • Broze Jr., G.J.1    Tollefsen, D.M.2
  • 19
    • 0026337077 scopus 로고
    • The coagulation cascade: Initiation, maintainance, and regulation
    • Davie EW, Fujikawa K, Kisiel W: The coagulation cascade: Initiation, maintainance, and regulation. Biochemistry 30:10363, 1991
    • (1991) Biochemistry , vol.30 , pp. 10363
    • Davie, E.W.1    Fujikawa, K.2    Kisiel, W.3
  • 20
    • 0023851758 scopus 로고
    • Tissue factor and hemostasis
    • Nemerson Y: Tissue factor and hemostasis. Blood 71:1, 1988
    • (1988) Blood , vol.71 , pp. 1
    • Nemerson, Y.1
  • 21
    • 0024292694 scopus 로고
    • The molecular basis of blood coagulation
    • Furie B. Furie BC: The molecular basis of blood coagulation. Cell 53:505, 1988
    • (1988) Cell , vol.53 , pp. 505
    • Furie, B.1    Furie, B.C.2
  • 22
    • 0023918199 scopus 로고
    • Blood coagulation factors V and VIII: Structural and functional similarities and their relationship to hemorrhagic and trombotic disorders
    • Kane WH, Davie EW: Blood coagulation factors V and VIII: Structural and functional similarities and their relationship to hemorrhagic and trombotic disorders. Blood 71:539, 1988
    • (1988) Blood , vol.71 , pp. 539
    • Kane, W.H.1    Davie, E.W.2
  • 23
    • 0001978360 scopus 로고
    • The physiology and biochemistry of factor V
    • Bloom AL, Forbes CD, Thomas DP, Tuddenham EGD (eds): Edinburgh, UK, Churchill Livingstone
    • Jenny RJ, Tracy PB, Mann KG: The physiology and biochemistry of factor V, in Bloom AL, Forbes CD, Thomas DP, Tuddenham EGD (eds): Haemostasis and Thrombosis. Edinburgh, UK, Churchill Livingstone, 1994, p 465
    • (1994) Haemostasis and Thrombosis , pp. 465
    • Jenny, R.J.1    Tracy, P.B.2    Mann, K.G.3
  • 24
    • 0027161205 scopus 로고
    • Molecular events that control the protein C anticoagulant pathway
    • Esmon CT: Molecular events that control the protein C anticoagulant pathway. Thromb Haemost 70:29, 1993
    • (1993) Thromb Haemost , vol.70 , pp. 29
    • Esmon, C.T.1
  • 25
    • 0027424531 scopus 로고
    • Cell mediated events that control blood coagulation and vascular injury
    • Esmon CT: Cell mediated events that control blood coagulation and vascular injury. Annu Rev Cell Biol 9:1, 1993
    • (1993) Annu Rev Cell Biol , vol.9 , pp. 1
    • Esmon, C.T.1
  • 26
    • 0025833619 scopus 로고
    • Protein S and C4b-binding protein: Components involved in the regulation of the protein C anticoagulant system
    • Dahlbäck B: Protein S and C4b-binding protein: Components involved in the regulation of the protein C anticoagulant system. Thromb Haemost 66:49, 1991
    • (1991) Thromb Haemost , vol.66 , pp. 49
    • Dahlbäck, B.1
  • 27
    • 0026591793 scopus 로고
    • The protein C anticoagulant pathway
    • Esmon CT: The protein C anticoagulant pathway. Arterioscler Thromb 12:135, 1992
    • (1992) Arterioscler Thromb , vol.12 , pp. 135
    • Esmon, C.T.1
  • 28
    • 0001976355 scopus 로고
    • The protein C anticoagulant system
    • Stamatoyannopoulos G, Nienhuis AW, Majerus PW, Varmus H (eds): Philadelphia, PA. Saunders
    • Dahlbäck B, Stenflo J: The protein C anticoagulant system, in Stamatoyannopoulos G, Nienhuis AW, Majerus PW, Varmus H (eds): The Molecular Basis of Blood Diseases. Philadelphia, PA. Saunders, 1994, p 599
    • (1994) The Molecular Basis of Blood Diseases , pp. 599
    • Dahlbäck, B.1    Stenflo, J.2
  • 29
    • 0026704809 scopus 로고
    • Regulation of blood coagulation by the protein C system
    • Walker FJ, Fay PJ: Regulation of blood coagulation by the protein C system. FASEB J 6:2561, 1992
    • (1992) FASEB J , vol.6 , pp. 2561
    • Walker, F.J.1    Fay, P.J.2
  • 30
    • 0028290275 scopus 로고
    • Factor V and protein S as synergistic cofactors to activated protein C in degradation of factor VIIIa
    • Shen L, Dahlbäck B: Factor V and protein S as synergistic cofactors to activated protein C in degradation of factor VIIIa. J Biol Chem 269:18735, 1994
    • (1994) J Biol Chem , vol.269 , pp. 18735
    • Shen, L.1    Dahlbäck, B.2
  • 31
    • 0027506706 scopus 로고
    • Contribution of plasma proteinase inhibitors to the regulation of activated protein C in plasma
    • Marlar RA, Kressin DC, Madden RM: Contribution of plasma proteinase inhibitors to the regulation of activated protein C in plasma. Thromb Haemost 69:16, 1993
    • (1993) Thromb Haemost , vol.69 , pp. 16
    • Marlar, R.A.1    Kressin, D.C.2    Madden, R.M.3
  • 32
    • 0027209683 scopus 로고
    • Factor VIII structure and function
    • Fay PJ: Factor VIII structure and function. Thromb Haemost 70:63, 1993
    • (1993) Thromb Haemost , vol.70 , pp. 63
    • Fay, P.J.1
  • 33
    • 0027744465 scopus 로고
    • Role of the membrane in the inactivation of factor Va by activated protein C
    • Kalifatis M, Mann KG: Role of the membrane in the inactivation of factor Va by activated protein C. J Biol Chem 268:27246, 1993
    • (1993) J Biol Chem , vol.268 , pp. 27246
    • Kalifatis, M.1    Mann, K.G.2
  • 34
    • 0023655669 scopus 로고
    • Proteolysis of factor Va by factor Xa and activated protein C
    • Odegaard B, Mann KG: Proteolysis of factor Va by factor Xa and activated protein C. J Biol Chem 262:11233, 1987
    • (1987) J Biol Chem , vol.262 , pp. 11233
    • Odegaard, B.1    Mann, K.G.2
  • 35
    • 0024558370 scopus 로고
    • The roles of protein C and thrombomodulin in the regulation of blood coagulation
    • Esmon CT: The roles of protein C and thrombomodulin in the regulation of blood coagulation. J Biol Chem 264:4743, 1989
    • (1989) J Biol Chem , vol.264 , pp. 4743
    • Esmon, C.T.1
  • 36
    • 0017283234 scopus 로고
    • A new vitamin K-dependent protein
    • Stenflo J: A new vitamin K-dependent protein. J Biol Chem 251:355, 1976
    • (1976) J Biol Chem , vol.251 , pp. 355
    • Stenflo, J.1
  • 37
    • 0017567792 scopus 로고
    • Anticoagulant properties of bovine plasma protein C following activation by thrombin
    • Kisiel W. Canfield WM, Ericsson LH, Davie EW: Anticoagulant properties of bovine plasma protein C following activation by thrombin. J Biol Chem 16:5824, 1977
    • (1977) J Biol Chem , vol.16 , pp. 5824
    • Kisiel, W.1    Canfield, W.M.2    Ericsson, L.H.3    Davie, E.W.4
  • 38
    • 0000650903 scopus 로고
    • Identification of an endothelial cell cofactor for thrombin catalyzed activation of protein C
    • Esmon CT, Owen WG: Identification of an endothelial cell cofactor for thrombin catalyzed activation of protein C. Proc Natl Acad Sci USA 78:2249, 1981
    • (1981) Proc Natl Acad Sci USA , vol.78 , pp. 2249
    • Esmon, C.T.1    Owen, W.G.2
  • 39
    • 0020063793 scopus 로고
    • Isolation of a membranebound cofactor for thrombin-catalyzed activation of protein C
    • Esmon NL, Owen WG, Esmon CT: Isolation of a membranebound cofactor for thrombin-catalyzed activation of protein C. J Biol Chem 257:859, 1982
    • (1982) J Biol Chem , vol.257 , pp. 859
    • Esmon, N.L.1    Owen, W.G.2    Esmon, C.T.3
  • 41
    • 84912717993 scopus 로고
    • A comparison of human prothrombin, factor IX, factor X, and protein S
    • Discipio RG, Hermodson MA, Yates SG, Davie EW: A comparison of human prothrombin, factor IX, factor X, and protein S. Biochemistry 16:698, 1977
    • (1977) Biochemistry , vol.16 , pp. 698
    • Discipio, R.G.1    Hermodson, M.A.2    Yates, S.G.3    Davie, E.W.4
  • 42
    • 0019332589 scopus 로고
    • Regulation of activated protein C by a new protein
    • Walker FJ: Regulation of activated protein C by a new protein. J Biol Chem 255:5521, 1980
    • (1980) J Biol Chem , vol.255 , pp. 5521
    • Walker, F.J.1
  • 43
    • 0019849380 scopus 로고
    • Regulation of activated protein C by protein S, the role of phospholipid in factor Va inactivation
    • Walker FJ: Regulation of activated protein C by protein S, the role of phospholipid in factor Va inactivation. J Biol Chem 256:11128, 1981
    • (1981) J Biol Chem , vol.256 , pp. 11128
    • Walker, F.J.1
  • 44
    • 0040426308 scopus 로고
    • High molecular weight complex in human plasma between vitamin K-dependent protein S and complement component C4b-binding protein
    • Dahlbäck B, Stenflo J: High molecular weight complex in human plasma between vitamin K-dependent protein S and complement component C4b-binding protein. Proc Natl Acad Sci USA 78:2512, 1981
    • (1981) Proc Natl Acad Sci USA , vol.78 , pp. 2512
    • Dahlbäck, B.1    Stenflo, J.2
  • 45
    • 0020638677 scopus 로고
    • Purification of human vitamin K-dependent protein S and its limited proteolysis by thrombin
    • Dahlbäck B: Purification of human vitamin K-dependent protein S and its limited proteolysis by thrombin. Biochem J 209:837, 1983
    • (1983) Biochem J , vol.209 , pp. 837
    • Dahlbäck, B.1
  • 46
    • 0020530378 scopus 로고
    • Purification of human C4b-binding protein and formation of its complex with vitamin K-dependent protein S
    • Dahlbäck B: Purification of human C4b-binding protein and formation of its complex with vitamin K-dependent protein S. Biochem J 209:847, 1983
    • (1983) Biochem J , vol.209 , pp. 847
    • Dahlbäck, B.1
  • 47
    • 0022929854 scopus 로고
    • a cofactor function of human and bovine protein S by C4b-binding protein
    • a cofactor function of human and bovine protein S by C4b-binding protein. J Biol Chem 261:12022, 1986
    • (1986) J Biol Chem , vol.261 , pp. 12022
    • Dahlbäck, B.1
  • 49
    • 0021741550 scopus 로고
    • Familial protein S deficiency is associated with recurrent thrombosis
    • Comp PC, Nixon RR, Cooper MR, Esmon CT: Familial protein S deficiency is associated with recurrent thrombosis. J Clin Invest 74:2082, 1984
    • (1984) J Clin Invest , vol.74 , pp. 2082
    • Comp, P.C.1    Nixon, R.R.2    Cooper, M.R.3    Esmon, C.T.4
  • 50
    • 0017875774 scopus 로고
    • Interaction of vitamin K dependent proteins with membranes
    • Nelsestuen GL, Kisiel W, Discipio RG: Interaction of vitamin K dependent proteins with membranes. Biochemistry 17:2134, 1978
    • (1978) Biochemistry , vol.17 , pp. 2134
    • Nelsestuen, G.L.1    Kisiel, W.2    Discipio, R.G.3
  • 51
    • 0021185743 scopus 로고
    • Protein S is essential for the activated protein C-catalyzed inactivation of platelet-associated factor Va
    • Suzuki K, Nishioka J, Matsuda J, Maruyama I, Hashimoto S: Protein S is essential for the activated protein C-catalyzed inactivation of platelet-associated factor Va. J Biochem 96:455, 1984
    • (1984) J Biochem , vol.96 , pp. 455
    • Suzuki, K.1    Nishioka, J.2    Matsuda, J.3    Maruyama, I.4    Hashimoto, S.5
  • 52
    • 0022000553 scopus 로고
    • Protein S is required for bovine platelets to support activated protein C binding and activity
    • Harris KW, Esmon CT: Protein S is required for bovine platelets to support activated protein C binding and activity. J Biol Chem 260:2007, 1985
    • (1985) J Biol Chem , vol.260 , pp. 2007
    • Harris, K.W.1    Esmon, C.T.2
  • 53
    • 0022612439 scopus 로고
    • Cultured bovine aortic endothelial cells promote activated protein C-protein S-mediated inactivation of factor Va
    • Stern DM, Nawroth PP, Harris KW, Esmon CT: Cultured bovine aortic endothelial cells promote activated protein C-protein S-mediated inactivation of factor Va. J Biol Chem 261:713, 1986
    • (1986) J Biol Chem , vol.261 , pp. 713
    • Stern, D.M.1    Nawroth, P.P.2    Harris, K.W.3    Esmon, C.T.4
  • 54
    • 0027076848 scopus 로고
    • Binding of anticoagulant vitamin K-dependent protein S to platelet-derived microparticles
    • Dahlbäck B, Wiedmer T, Sims PJ: Binding of anticoagulant vitamin K-dependent protein S to platelet-derived microparticles. Biochemistry 31:12769, 1992
    • (1992) Biochemistry , vol.31 , pp. 12769
    • Dahlbäck, B.1    Wiedmer, T.2    Sims, P.J.3
  • 55
    • 0026722694 scopus 로고
    • The effect of phospholipids, calcium ions and protein S on rate constants of human factor Va inactivation by activated human protein C
    • Bakker H, Tans G, Janssen-Claessen T, Thomassen MCLGD, Hemker HC, Griffin JH, Rosing J: The effect of phospholipids, calcium ions and protein S on rate constants of human factor Va inactivation by activated human protein C. Eur J Biochem 208:171, 1992
    • (1992) Eur J Biochem , vol.208 , pp. 171
    • Bakker, H.1    Tans, G.2    Janssen-Claessen, T.3    Thomassen, M.C.L.G.D.4    Hemker, H.C.5    Griffin, J.H.6    Rosing, J.7
  • 56
    • 0023731990 scopus 로고
    • Kinetics of inactivation of membrane-bound factor V by activated protein C
    • Solymoss S, Tucker MM, Tracy PB: Kinetics of inactivation of membrane-bound factor V by activated protein C. J Biol Chem 263:14884, 1988
    • (1988) J Biol Chem , vol.263 , pp. 14884
    • Solymoss, S.1    Tucker, M.M.2    Tracy, P.B.3
  • 58
    • 0027404562 scopus 로고
    • Binding of protein S to factor Va associated with inhibition of prothrombinase that is independent of activated protein C
    • Heeb MJ, Mesters RM, Tans G, Rosing J, Griffin JH: Binding of protein S to factor Va associated with inhibition of prothrombinase that is independent of activated protein C. J Biol Chem 268:2872, 1993
    • (1993) J Biol Chem , vol.268 , pp. 2872
    • Heeb, M.J.1    Mesters, R.M.2    Tans, G.3    Rosing, J.4    Griffin, J.H.5
  • 60
    • 0021238080 scopus 로고
    • Effects of thrombomodulin and coagulation factor Va-light chain on protein C activation in vitro
    • Salem HH, Esmon NL, Esmon CT, Majerus PW: Effects of thrombomodulin and coagulation factor Va-light chain on protein C activation in vitro. J Clin Invest 73:968, 1984
    • (1984) J Clin Invest , vol.73 , pp. 968
    • Salem, H.H.1    Esmon, N.L.2    Esmon, C.T.3    Majerus, P.W.4
  • 61
    • 0023818347 scopus 로고
    • The frequency of type I heterozygous protein S and protein C deficiency in 141 unrelated young patients with venous thrombosis
    • Gladson CL, Scharrer I, Hach V, Beck KH, Griffin JH, The frequency of type I heterozygous protein S and protein C deficiency in 141 unrelated young patients with venous thrombosis. Thromb Haemost 59:18, 1988
    • (1988) Thromb Haemost , vol.59 , pp. 18
    • Gladson, C.L.1    Scharrer, I.2    Hach, V.3    Beck, K.H.4    Griffin, J.H.5
  • 62
    • 0024507770 scopus 로고
    • The clinical spectrum of heterozygous protein C deficiency in a large New England kindred
    • Bovill EG, Bauer KA, Dickermann JD, Callas P, West B: The clinical spectrum of heterozygous protein C deficiency in a large New England kindred. Blood 73:712, 1989
    • (1989) Blood , vol.73 , pp. 712
    • Bovill, E.G.1    Bauer, K.A.2    Dickermann, J.D.3    Callas, P.4    West, B.5
  • 64
    • 0026072398 scopus 로고
    • The spectrum of genetic defects in a panel of 40 Dutch families with symptomatic protein C deficiency type I: Heterogeneity and founder effects
    • Reitsma PH, Poort SR, Allaart CF, Briët E, Bertina RM: The spectrum of genetic defects in a panel of 40 Dutch families with symptomatic protein C deficiency type I: Heterogeneity and founder effects. Blood 78:890, 1991
    • (1991) Blood , vol.78 , pp. 890
    • Reitsma, P.H.1    Poort, S.R.2    Allaart, C.F.3    Briët, E.4    Bertina, R.M.5
  • 65
    • 0023233223 scopus 로고
    • Absence of thrombosis in subjects with heterozygous protein C deficiency
    • Miletich JP, Sherman L, Broze GJ Jr: Absence of thrombosis in subjects with heterozygous protein C deficiency. N Engl J Med 317:991, 1987
    • (1987) N Engl J Med , vol.317 , pp. 991
    • Miletich, J.P.1    Sherman, L.2    Broze Jr., G.J.3
  • 68
    • 0025244937 scopus 로고
    • Neonatal purpura fulminans due to homozygous protein C or protein S deficiencies
    • Marlar RA, Neumann A: Neonatal purpura fulminans due to homozygous protein C or protein S deficiencies. Semin Thromb Hemost 16:299, 1990
    • (1990) Semin Thromb Hemost , vol.16 , pp. 299
    • Marlar, R.A.1    Neumann, A.2
  • 69
    • 0026409651 scopus 로고
    • Treatment of homozygous protein C deficiency and neonatal purpura fulminans with purified protein C concentrate
    • Dreyfus M, Magny JF, Bridey F, Schwarz HP, Planché C, Dehan M, Tchernia G: Treatment of homozygous protein C deficiency and neonatal purpura fulminans with purified protein C concentrate. N Engl J Med 325:1565, 1991
    • (1991) N Engl J Med , vol.325 , pp. 1565
    • Dreyfus, M.1    Magny, J.F.2    Bridey, F.3    Schwarz, H.P.4    Planché, C.5    Dehan, M.6    Tchernia, G.7
  • 71
    • 18544395863 scopus 로고
    • Protein S deficiency associated with "juvenile" arterial and venous thrombosis
    • Mannucci PM, Tripodi A, Bertina RM: Protein S deficiency associated with "juvenile" arterial and venous thrombosis. Thromb Haemost 55:440, 1986
    • (1986) Thromb Haemost , vol.55 , pp. 440
    • Mannucci, P.M.1    Tripodi, A.2    Bertina, R.M.3
  • 73
    • 0022636454 scopus 로고
    • An abnormal plasma distribution of protein S occurs in functional protein S deficiency
    • Comp PC, Doray D, Patton D, Esmon CT: An abnormal plasma distribution of protein S occurs in functional protein S deficiency. Blood 67:504, 1986
    • (1986) Blood , vol.67 , pp. 504
    • Comp, P.C.1    Doray, D.2    Patton, D.3    Esmon, C.T.4
  • 74
    • 0021720421 scopus 로고
    • Recurrent thromboembolism in patients with a partial deficiency of protein S
    • Comp PC, Esmon CT: Recurrent thromboembolism in patients with a partial deficiency of protein S. N Engl J Med 311:1525, 1984
    • (1984) N Engl J Med , vol.311 , pp. 1525
    • Comp, P.C.1    Esmon, C.T.2
  • 77
    • 0027953010 scopus 로고
    • Protein S Tokushima: Abnormal molecule with a substitution of Glu for Lys-155 in the second epidermal growth factor-like domain of protein S
    • Hayashi T, Nishioka J, Shigekiyo T, Saito S, Suzuki K: Protein S Tokushima: Abnormal molecule with a substitution of Glu for Lys-155 in the second epidermal growth factor-like domain of protein S. Blood 83:683, 1994
    • (1994) Blood , vol.83 , pp. 683
    • Hayashi, T.1    Nishioka, J.2    Shigekiyo, T.3    Saito, S.4    Suzuki, K.5
  • 78
    • 0027742936 scopus 로고
    • Resistance to activated protein C in nine thrombophilic families: Interference in a protein S functional assay
    • Faioni EM, Franchi F, Asti D, Sacchi E, Bernardi F, Mannucci PM: Resistance to activated protein C in nine thrombophilic families: Interference in a protein S functional assay. Thromb Haemost 70:1067, 1993
    • (1993) Thromb Haemost , vol.70 , pp. 1067
    • Faioni, E.M.1    Franchi, F.2    Asti, D.3    Sacchi, E.4    Bernardi, F.5    Mannucci, P.M.6
  • 79
    • 23444453692 scopus 로고
    • Three novel mutations in five unrelated subjects with hereditary protein S deficiency type I
    • Reitsma PH, Ploos van Amstel HK, Bertina RM: Three novel mutations in five unrelated subjects with hereditary protein S deficiency type I. J Clin Invest 93:486, 1994
    • (1994) J Clin Invest , vol.93 , pp. 486
    • Reitsma, P.H.1    Ploos Van Amstel, H.K.2    Bertina, R.M.3
  • 80
    • 0026029146 scopus 로고
    • A 5.3-kb deletion including exon XIII of the protein S a gene occurs in two protein S-deficient families
    • Schmidel DK, Nelson RM, Broxson EH, Comp PC, Marlar RA, Long GL: A 5.3-kb deletion including exon XIII of the protein S a gene occurs in two protein S-deficient families. Blood 77:551, 1991
    • (1991) Blood , vol.77 , pp. 551
    • Schmidel, D.K.1    Nelson, R.M.2    Broxson, E.H.3    Comp, P.C.4    Marlar, R.A.5    Long, G.L.6
  • 83
    • 0028098218 scopus 로고
    • Inherited resistance to activated protein C is corrected by anticoagulant cofactor activity found to be a property of factor V
    • Dahlbäck B, Hildebrand B: Inherited resistance to activated protein C is corrected by anticoagulant cofactor activity found to be a property of factor V. Proc Natl Acad Sci USA 81:1396, 1994
    • (1994) Proc Natl Acad Sci USA , vol.81 , pp. 1396
    • Dahlbäck, B.1    Hildebrand, B.2
  • 84
    • 85088329402 scopus 로고
    • Resistance to activated protein C as a basis for venous thromboembolism associated with pregnancy and oral contraceptives
    • in revision
    • Hellgren M, Svensson PJ, Dahlbäck B: Resistance to activated protein C as a basis for venous thromboembolism associated with pregnancy and oral contraceptives. Am J Obstet Gyn 1994 (in revision)
    • (1994) Am J Obstet Gyn
    • Hellgren, M.1    Svensson, P.J.2    Dahlbäck, B.3
  • 85
    • 0028037137 scopus 로고
    • Identification of the same factor V gene mutation in 47 out of 50 thrombosis-prone families with inherited resistance to activated protein C
    • Zöller B, Svensson PJ, He X, Dahlbäck B: Identification of the same factor V gene mutation in 47 out of 50 thrombosis-prone families with inherited resistance to activated protein C. J Clin Invest 94:2521, 1994
    • (1994) J Clin Invest , vol.94 , pp. 2521
    • Zöller, B.1    Svensson, P.J.2    He, X.3    Dahlbäck, B.4
  • 86
    • 0027428481 scopus 로고
    • Anticoagulant protein C pathway defective in a majority of thrombophilic patients
    • Griffin JH, Evatt B, Wideman C, Fernandez JA: Anticoagulant protein C pathway defective in a majority of thrombophilic patients. Blood 82:1989, 1993
    • (1993) Blood , vol.82 , pp. 1989
    • Griffin, J.H.1    Evatt, B.2    Wideman, C.3    Fernandez, J.A.4
  • 87
    • 0028326025 scopus 로고
    • The prevalence of poor anticoagulant response to activated protein C (APC resistance) among patients suffering from stroke or venous thrombosis and among healthy subjects
    • Halbmayer WM, Haushofer A, Schön R, Fischer M: The prevalence of poor anticoagulant response to activated protein C (APC resistance) among patients suffering from stroke or venous thrombosis and among healthy subjects. Blood Coagul Fibrinol 5:51, 1994
    • (1994) Blood Coagul Fibrinol , vol.5 , pp. 51
    • Halbmayer, W.M.1    Haushofer, A.2    Schön, R.3    Fischer, M.4
  • 88
    • 0028351510 scopus 로고
    • Frequency of a defective response to activated protein C in patients with a history of venous thrombosis
    • Cadroy Y, Sié P, Boneu B: Frequency of a defective response to activated protein C in patients with a history of venous thrombosis. Blood 83:2008, 1994
    • (1994) Blood , vol.83 , pp. 2008
    • Cadroy, Y.1    Sié, P.2    Boneu, B.3
  • 89
    • 84939685630 scopus 로고
    • Arterial and venous thromboembolism with fatal outcome in a young man with inherited resistance to activated protein C
    • Lindblad B, Svensson PJ, Dahlbäck B: Arterial and venous thromboembolism with fatal outcome in a young man with inherited resistance to activated protein C. Lancet 343:917, 1994
    • (1994) Lancet , vol.343 , pp. 917
    • Lindblad, B.1    Svensson, P.J.2    Dahlbäck, B.3
  • 90
    • 85088327173 scopus 로고
    • Myocardial infarction in two young women associated with homozygous resistance to activated protein C
    • Holm J, Zöller B, Svensson PJ, Berntorp E, Erhardt L, Dahlbäck B: Myocardial infarction in two young women associated with homozygous resistance to activated protein C. Lancet 344:952, 1994
    • (1994) Lancet , vol.344 , pp. 952
    • Holm, J.1    Zöller, B.2    Svensson, P.J.3    Berntorp, E.4    Erhardt, L.5    Dahlbäck, B.6
  • 91
    • 0028765167 scopus 로고
    • Bad blood by mutation
    • Majerus PW: Bad blood by mutation. Nature 369:14, 1994
    • (1994) Nature , vol.369 , pp. 14
    • Majerus, P.W.1
  • 92
    • 0028047763 scopus 로고
    • Hypercoagulability - A new cofactor in the protein C anticoagulant pathway
    • Bauer KA: Hypercoagulability - A new cofactor in the protein C anticoagulant pathway. N Engl J Med 330:566, 1994
    • (1994) N Engl J Med , vol.330 , pp. 566
    • Bauer, K.A.1
  • 93
    • 0023001694 scopus 로고
    • Bovine coagulation factor V visualized with electron microscopy; ultrastructure of the isolated activated forms and of the activation fragments
    • Dahlbäck B: Bovine coagulation factor V visualized with electron microscopy; ultrastructure of the isolated activated forms and of the activation fragments. J Biol Chem 261:9495, 1986
    • (1986) J Biol Chem , vol.261 , pp. 9495
    • Dahlbäck, B.1


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