Genetic and Enzymatic Evidence for Lewis Enzyme Expression in Lewis-negative Cancer Patients

Cancer Research

Volumn 55, Issue 7, 1995, Pages 1473-1478

  Yazawa, Shin ^a   Nishihara, Shoko ^a   Iwasaki, Hiroko ^a   Asao, Takayuki ^a   Nagamachi, Yukio ^b   Matta, Khushi L ^c   Narimatsu, Hisashi ^d  

^a GUNMA UNIVERSITY   (Japan)

^b Department of Legal Medicine and First Department of Surgery ^*  (Japan)

^c ROSWELL PARK CANCER INSTITUTE   (United States)

^d SOKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FUCOSYLTRANSFERASE;

ARTICLE; BLOOD GROUP LEWIS SYSTEM; CONTROLLED STUDY; GENOTYPE; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALIGNANT NEOPLASTIC DISEASE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

BASE SEQUENCE; ERYTHROCYTES; ESOPHAGEAL NEOPLASMS; FUCOSYLTRANSFERASES; GASTROINTESTINAL NEOPLASMS; GENOTYPE; HUMAN; LEWIS BLOOD-GROUP SYSTEM; MOLECULAR SEQUENCE DATA; PHENOTYPE; SALIVA; SUPPORT, NON-U.S. GOV'T;

EID: 0028953811     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Watkins, W.M. Biochemistry and genetics of the, ABO, Lewis and P blood group systems. Adv. Hum. Genet. 10: 1-136, 1980.
2. Kukowska-Latallo, J.F. Larsen, R.D. Nair, R.P. and Lowe, J.B. A cloned human cDNA determines expression of a mouse stage-specific embryonic antigen and the Lewis blood group cr(l, 3/l, 4) fucosyltransferase. Genes Dev. 4: 1288-1303, 1990.
3. Nishihara, S. Yazawa, S. Iwasaki, H. Nakazato, M. Kudo, T. Ando, T. and Narimatsu, H. cr(l, 3/1, 4)Fucosyltransferase (FucT-III) gene is inactivated by a single amino acid substitution in Lewis histo-blood type negative individuals. Biochem. Biophys. Res. Commun. 196: 624-631, 1993.
4. Yazawa, S. and Fumkawa, K. a-Fucosyltransferases related to biosynthesis of blood group substances in human saliva. J. Immunogenet. 7: 137-148, 1980.
5. Yazawa, S. Madiyalakan, R. Jain, R.K. Shimoda, N. and Matta, K.L. Use of benzyl 2-acetamido-2-deoxy-3-0-(2-0-methyl-D-galactosyl)-D-glucopyranoside [2′-0-methyllacto-W-biose I0Bn] as a specific acceptor for GDP-fucose: A/-acctylglu-cosaminide a(l-4)-L-fucosyltransferase. Anal. Biochem. 187: 374-378, 1990.
6. Yazawa, S. Nakamura, J. Asao, T. Nagamachi, Y. Sagi, S. Matta, K.L. Tachikawa, T. and Akamatsu, S. Aberrant a l->2fucosyl transferases found in human colorectal carcinoma involved in the accumulation of Leb and Y antigens in colorectal tumors. Jpn. J. Cancer Res. 84: 989-995, 1993.
7. Hirano, K. Kawa, S. Oguchi, H. Kobayashi, T. Yonekura, H. Ogata, H. and Homma, T. Loss of Lewis antigen expression on erythrocytes in some cancer patients with high serum CA19-9 levels. J. Natl. Cancer Inst. 79: 1261-1268, 1987.
8. Yazawa, S. Asao, T. Izawa, H. Miyamoto, Y. and Matta, K.L. The presence of CA19-9 in serum and saliva from Lewis blood-group negative cancer patients. Jpn. J. Cancer Res. 79: 538-543, 1988.
9. Hammer, L. Mansson, S. Rohr, T. Chester, M.A. Ginsburg, V. Lundblad, A. and Zopf, D. Lewis-phenotype of erythrocytes and Leb active glycolipid in serum of pregnant women. Vox Sang. 40: 27-33, 1981.
10. Stigendal, L. Olsson, R. Rydberg, L. and Samuelsson, B.E. Blood group Lewis phenotype on erythrocytes and in saliva in alcoholic pancreatitis and chronic liver disease. J. Clin. Pathol. 37: 778-786, 1984.
11. Makni, S. Dalix, A.M. Caillard, T. Compagnon, B. Le Pendu, J. Ayed, K. and Oriol, R. Discordance between red cell and saliva Lewis phenotypes in patients with hydatid cysts. Exp. Clin. Immunogenet. 4: 136-143, 1987.
12. Ernst, C. Atkinson, B. Wysocka, M. Blaszczyk, M. Herlyn, M. Sears, H. Steplewsky, Z. and Koprowsky, H. Monoclonal antibody localization of Lewis antigens in fixed tissue. Lab. Invest. 50: 394-400, 1984.
13. Limas, C. Detection of urothelial Lewis antigens with monoclonal antibodies. Am. J. Pathol. 125: 515-523, 1986.
14. Langkilde, N.C. Wolf, H. and 0rntoft, T.F. Lewis antigen expression in benign and malignant tissues from RBC Le(a-b-) cancer patients. Br. J. Haematol. 79: 493-499, 1991.
15. 0rntoft, T.F. Holmes, E.H. Johnson, P. Hakomori, S. and Clausen, H. Differential tissue expression of the Lewis blood group antigens: enzymatic, immunohistologic, and immunochemical evidence for Lewis a and b antigen expression in Le(a-b-) individuals. Blood, 77: 1389-13%, 1991.
16. Nishihara, S. Narimatsu, H. Iwasaki, H. Yazawa, S. Akamatsu, S. Ando, T. Seno, T. and Narimatsu, I. Molecular genetic analysis of the human Lewis histo-blood group system. J. Biol. Chem. 269: 29271-29278, 1994.
17. Yazawa, S. Akamatsu, S. Tachikawa, T. Naito, H. Nakamura, J. Asao, T. Magamachi, Y. Nakajima, T. Shin, S. and Qua, D. Development and characterization of a novel anti-fucosylated antigen monoclonal antibody YB-2 and its usefulness in the immunohistochemical diagnosis of colorectal cancer. Jpn. J. Cancer Res. 84: 641-648, 1993.
18. Technical Manual of the American Association of Blood Banks, Ed. 8. Washington DC: American Association of Blood Banks, 1981.
19. Yazawa, S. Takeya, A. Hosomi, 0. Nakajima, T. Shimoda, N. Ohi, H. Tachikawa, T. Piscorz, C.F. Jain, R.K. and Matta, K.L. Use of synthetic H disaccharides as acceptors for detecting activities of UDP-GalNAc: Fucorl-2Gal/5-R crl-<3-#-acetylgalactosaminyltransferase in plasma samples from blood group A subgroups. Clin. Chem. 38: 2392-2395, 1992.
20. Chester, M.A. and Watkins, W.M. a-L-Fucosyltransferases in human submaxillary gland and stomach tissues associated with the H, Lea and Leb blood group characters and ABH secretor status. Biochem. Biophys. Res. Commun. 34: 835-842, 1969.
21. Grollman, E.F. Kobata, A. and Ginsburg, V. An enzymatic basis for Lewis blood types in man. J. Clin. Invest. 48: 1489-1494, 1969.
22. Lowe, J.B. Kukowska-Latallo, J.F. Nair, R.P. Larsen, R.D. Marks, R.M. Macher, B.A. Kelly, R.J. and Ernst, L.K. Molecular cloning of a human fucosyltransferase gene that determines expression of the Lewis x and VIM-2 epitopes but not ELAM-1-dependent cell adhesion. J. Biol. Chem. 266: 17467-17477, 1991.
23. Kumar, R. Potvin, B. Muller, W.A. and Stanley, P. Cloning of a human cr(l, 3)-fucosyltransferase gene that encodes ELFT but does not confer ELAM-1 recognition on Chinese hamster ovary cell transfectants. J. Biol. Chem. 266: 21777-21783, 1991.
24. Goelz, S.E. Hession, C. Goff, D. Griffiths, B. Tizard, R. Newman, B. Chi-Rosso, G. and Lobb, R. ELFT: a gene that directs the expression of an ELAM-1 ligand. Cell, 63: 1349-1356, 1990.
25. Weston, B.W. Nair, R.P. Larsen, R.D. and Lowe, J.B. Isolation of a novel human ot(l, 3)r ucosyltransferase gene and molecular comparison to the human Lewis blood group a(l, 3/l, 4)rucosyltransferase gene. J. Biol. Chem. 267: 4152-4160, 1992.
26. Koszdin, K.L. and Bowen, B.R. The cloning and expression of a human a-l, 3fu-cosyltransferase capable of forming the E-selectin ligand. Biochem. Biophys. Res. Commun. 187: 152-157, 1992.
27. Weston, B.W. Smith, P.L. Kelly, R.J. and Lowe, J.B. Molecular cloning of a fourth member of a human a(l, 3)rucosyltransferase gene family. J. Biol. Chem. 267: 24575-24584, 1992.
28. Nishihara, S. Nakazato, M. Kudo, T. Kimura, H. Ando, T. and Narimatsu, H. Human a-l, 3fucosyltransferase (Fuc-TVI) gene is located at only 13 kb 3′ to the Lewis type fucosyltransferase (Fuc-TIII) gene on chromosome 19. Biochem. Biophys. Res. Commun. 190: 42-46, 1993.
29. Sasaki, K. Kurata, K. Funayama, K. Nagata, M. Watanabe, E. Ohta, S. Hanai, N. and Nishi, T. Expression cloning of a novel a 1, 3-rucosyltransferase that is involved in biosynthesis of the sialyl Lewis x carbohydrate determinants in leukocytes. J. Biol. Chem. 269: 14730-14737, 1994.
30. Mollicone, R. Reguigne, I. Kelly, R.J. Fletcher, A. Watt, J. Chatfield, S. Aziz, A. Cameron, H.S. Weston, B.W. Jowe, J.B. and Oriol, R. Molecular basis for Lewis a(l, 3/l, 4)-fucosyltransferase gene deficiency (FUT3) found in Lewis-negative Indonesian pedigrees. J. Biol. Chem. 269: 20987-20994, 1994.
31. Langkilde, N.C. Wolf, H. Meldgard, P. and 0rntoft, T.F. Frequency and mechanism of Lewis antigen expression in human urinary bladder and colon carcinoma patients. Br. J. Cancer, 63: 583-586, 1991.
32. Bjork, S. Breimer, M.E. Hasson, G.C. Karlsson, K.A. and Leffler, H. Structures of blood group glycoshingolipids of human small intestine: a relation between the expression of fucolipids of epithelial cells and the ABO, Le and Se phenotypes of the donor. J. Biol. Chem. 262: 6758-6765, 1987.
33. Marcus, D.M. and Cass, L.E. Glycosphingolipids with Lewis blood group activity: uptake by human erythrocytes. Science (Washington DC), 164: 553-554, 1969.