The Inhibitory Activity of an HIV Type 1 Peptide Correlates with Its Ability to Interact with a Leucine Zipper Structure

AIDS Research and Human Retroviruses

Volumn 11, Issue 3, 1995, Pages 323-325

  Wild, Carl ^a   Greenwell, Teresa ^a   Shugars, Diane ^a   Rimsky Clarke, Laurence ^a   Matthews, Thomas ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; DP 107; DP 208; DP 209; DP 210; DP 211; DP 213; DP 219; ENFUVIRTIDE; GLYCOPROTEIN GP 41; LEUCINE ZIPPER PROTEIN; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG; VIRUS PROTEIN;

AMINO TERMINAL SEQUENCE; ANTIVIRAL ACTIVITY; CARBOXY TERMINAL SEQUENCE; CELL FUSION; CIRCULAR DICHROISM; DRUG STRUCTURE; GENE DELETION; HUMAN IMMUNODEFICIENCY VIRUS 1; LETTER; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; VIRUS INHIBITION;

AMINO ACID SEQUENCE; ANTIVIRAL AGENTS; CIRCULAR DICHROISM; COMPARATIVE STUDY; HIV ENVELOPE PROTEIN GP41; HIV-1; LEUCINE ZIPPERS; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0028953212     PISSN: 08892229     EISSN: 19318405     Source Type: Journal    
DOI: 10.1089/aid.1995.11.323     Document Type: Letter

References (7)

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2. Wild C, Shugars D, Greenwell T, McDanal C, and Matthews T: Peptides corresponding to a predictive a-helical domain of HIV-1 gp41 are potent inhibitors of virus infection. Proc Natl Acad Sci USA 1994;91:9770-9774.
3. Wild C, Oas T, McDanal C, Bolognesi D, and Matthews T: A synthetic peptide inhibitor of human immunodeficiency virus replication: Correlation between solution structure and viral inhibition. Proc Natl Acad Sci USA 1992;89:10537-10541.
4. Delwart E, Mosialos G, and Gilmore T: Retroviral envelope glycoproteins contain a “leucine zipper”-like repeat. AIDS Res Hum Retroviruses 1989;6(6):703-706.
5. Cantor C and Schimmel P: Biophysical Chemistry, Part II: Techniques for the Study of Biological Structure and Function. W. H. Freeman and Company, New York, 1980, pp. 838-843.
6. Jiang S, Lin K, Strick N, and Neurath A: Inhibition by a HIV-1 peptide. Nature (London) 1993;365:113.
7. Jiang S, Lin K, Strick N, and Neurath A: Inhibition of HIV-1 infection by a fusion domain binding peptide from the HIV-1 envelope glycoprotein gp41. Biochem Biophys Res Commun 1993; 195: 533-538.