Synthesis and Antiinflammatory Activity of Certain 5,6,7,8-Tetrahydroquinolines and Related Compounds

Journal of Medicinal Chemistry

Volumn 38, Issue 9, 1995, Pages 1473-1481

  Calhoun, William ^a   Carlson, Richard P ^a   Crossley, Roger ^a   Datko, Louis J ^a   Dietrich, Scott ^a   Heatherington, Kenneth ^a   Marshall, Lisa A ^a   Meade, Peter J ^a   Opalko, Albert ^a   Shepherd, Robin G ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 AMINO 1 (3 TRIFLUOROMETHYLPHENYL) 2 PYRAZOLINE; 5,6,7,8 TETRAHYDROQUINOLINE DERIVATIVE; 6,7,8,9 TETRAHYDRO 3 METHYL ALPHA (4 METHYLPHENYL) 5H CYCLOHEPTA[B]PYRIDINE 2 METHANOL; 6,7,8,9 TETRAHYDRO 5H CYCLOHEPTA[B]PYRIDINE DERIVATIVE; ANTIULCER AGENT; ARACHIDONATE 5 LIPOXYGENASE; BENZYLIDENE DERIVATIVE; CL 1004; IBUPROFEN; LIPOXYGENASE INHIBITOR; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN SYNTHASE INHIBITOR; PYRIDINE DERIVATIVE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG; WY 28342; ZILEUTON;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTHRITIS; ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; FEMALE; FEVER; INTRAGASTRIC DRUG ADMINISTRATION; MALE; NEUTROPHIL; NONHUMAN; ORAL DRUG ADMINISTRATION; PAW EDEMA; RAT; STEREOCHEMISTRY; STOMACH DISEASE;

EID: 0028946299     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00009a008     Document Type: Article

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