Metabolism and bioactivation of clozapine by human liver in vitro

Journal of Pharmacology and Experimental Therapeutics

Volumn 272, Issue 3, 1995, Pages 984-990

  Pirmohamed, M ^a   Williams, D ^a   Madden, S ^a   Templeton, E ^a   Park, B K ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CLOZAPINE; COUMARIN; CYTOCHROME P450 ISOENZYME; DRUG METABOLITE; ENZYME INHIBITOR; FURAFYLLINE; GLUTATHIONE; KETOCONAZOLE; NITROPHENOL; NORCLOZAPINE; QUINIDINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SULFAPHENAZOLE; THIAMAZOLE;

ARTICLE; CONTROLLED STUDY; DRUG ACTIVATION; DRUG CONJUGATION; DRUG METABOLISM; DRUG OXIDATION; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG TRANSFORMATION; GENOTYPE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; LIVER METABOLISM; LIVER MICROSOME; PRIORITY JOURNAL; RADIOMETRY;

ADULT; ASCORBIC ACID; BIOTRANSFORMATION; CHILD; CLOZAPINE; CYTOCHROME P-450 CYP2D6; CYTOCHROME P-450 ENZYME SYSTEM; FEMALE; GENOTYPE; HUMAN; IN VITRO; MICROSOMES, LIVER; MIXED FUNCTION OXYGENASES; SULFHYDRYL COMPOUNDS; SUPPORT, NON-U.S. GOV'T;

EID: 0028944753     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (0)