Inhibition of hepatocyte growth factor-induced motility and in vitro invasion of human colon cancer cells by gamma-linolenic acid

British Journal of Cancer

Volumn 71, Issue 4, 1995, Pages 744-752

  Jiang, W G ^a   Hiscoxl, S ^a   Hallett, M B ^a   Scott, C ^b   Horrobin, D F ^b  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b Scotia Pharmaceuticals Ltd   (United Kingdom)

Author keywords

Colon cancer; E cadherin; Gamma linolenic acid; Hepatocyte growth factor; Invasion; Motility

Indexed keywords

CELL ADHESION MOLECULE; ESSENTIAL FATTY ACID; GAMMA LINOLENIC ACID; LITHIUM SALT; MATRIGEL; SCATTER FACTOR; UVOMORULIN;

ARTICLE; CANCER INVASION; CELL MOTILITY; COLON CANCER; CONTROLLED STUDY; DISSOCIATION; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

ARACHIDONIC ACID; CADHERINS; CELL ADHESION; CELL LINE; CELL MOVEMENT; COLONIC NEOPLASMS; COMPARATIVE STUDY; EXTRACELLULAR MATRIX; GAMMA-LINOLENIC ACID; HEPATOCYTE GROWTH FACTOR; HUMAN; LINOLEIC ACID; LINOLEIC ACIDS; NEOPLASM INVASIVENESS; RECEPTORS, FIBRONECTIN; SUPPORT, NON-U.S. GOV'T; TUMOR CELLS, CULTURED;

EID: 0028941798     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.1995.145     Document Type: Article

References (40)

1. ALBINI A, IWAMOTO Y, KLEINMAN HK, MARTIN GR, AARONSON SA, KOZLOWSKI JM AND MCEWAN RN. (1987). A rapid in vitro assay for quantitating the invasive potential of tumor cellsCancer Res., 47, 3239–3245.
2. ALLEN-MERSH TG. (1989). Colorectal liver metastasesJ. R. Soc. Med., 82, 2–3.
3. AUGUST DA, OTTOW RT AND SUGARBAKER PH. (1984). Clinical perspective of human colorectal cancer metastasesCancer Metastases Rev., 3, 303–324.
4. BEGIN ME, ELLS G, DAS UN AND HORROBIN DF. (1986). Differential killing of human carcinoma cells supplemented with n-3 and n-6 polyunsaturated fatty acidsJ. Natl Cancer Inst., 77, 1053–1062.
5. BEGIN ME, ELLS G, DAS UN AND HORROBIN DF. (1988). Polyunsaturated fatty acids induced cytotoxicity against tumor cells and its relationship to lipid peroxidationJ. Natl Cancer Inst., 80, 188–194.
6. BEHRENS J, WEIDNER KM, FRIXEN UH, SCHIPPER JH, SACHS M, ARAKAKI N, DAIKUHARA Y AND BIRCHMEIER W. (1991). The role of E-cadherin and scatter factor in tumour invasion and cell motility. In Cell Motility Factors, Goldberg ID (eds). pp. 109-126. Birkharser: Basle.
7. BOTHA JH, ROBINSON KM, RAMCHURREN N AND NORMAN RJ. (1989). The role of prostaglandins in the inhibition of cultured carcinoma cell growth produced by gamma-linolenic acidProstaglandins Leukotrienes Essential Fatty Acids, 35, 119–123.
8. DOKI Y, SHIOZAKI H, TAHARA H, INOUE M, ODA H, IIHARA K, KADOWAKI T, TAKEICHI M AND MORI T. (1993). Correlation between E-cadherin expression and invasiveness in vitro in a human esophageal cancer cell lineCancer Res., 53, 3421–3426.
9. DONALDSON GA, WELCH JP. (1974). Management of cancer of the colonSurg. Clin. N. Am., 54, 713–730.
10. EISENBERG B, DE COSSE JJ, HARFORD F AND MICHALEK J. (1982). Carcinoma of the colon and rectum - the natural history reviewed in 1704 patientsCancer, 49, 1131–1134.
11. FALCONER JS, ROSS JA, FEARON KCH, HAWKINS RA, O’RIOR-DAIN MG AND CARTER DC. (1994). Effects of eicosapentaenoic acid and other fatty acids on the growth in vitro of human pancreatic cancer cell linesBr. J. Cancer, 69, 826–832.
12. FURUKAWA T, WATANABE M, KUMOTA T, DASE S, FUJITA S, YAMAMOTO T, SAIKAWA Y, KUO TH, TANINO H, KURIHARA N, KAWANO Y, KAWAMOTO K, SUTO A, TERAMOTO T, ISHIBIKI K AND KITAJIMA M. (1993). Significance of in vitro attachment of human colon cancer to extracellular matrix proteins in experimental and clinical liver metastasisJ. Surg. Oncol., 53, 1016.
13. GHERARDI E, GRAY J, STOKER M, PERRYMAN M AND FURLONG R. (1989). Purification of scatter factor, a fibroblast-derived basic protein that modulates epithelial interactions and movementProc. Natl Acad. Sci. USA, 86, 5844–5848.
14. HAYASHI Y, FUKUSHIMA S, KISHIMOTO S, KAWAGUCH T, NUMATA M, ISODA Y, HIRANO J AND NAKANO M. (1992). Anticancer effects of free polyunsaturated fatty acids in an oily lym- phographic agent following intrahepatic arterial administration to a rabbit bearing VX-2 tumorCancer Res., 52, 400–405.
15. HONN KV, NELSON KK, RENAUD C, BAZAZ R, DIGLIO CA AND TIMAR J. (1992). Fatty acid modulation of tumor cell adhesion to microvessel endothelium and experimental metastasisProstaglandins, 44, 413–429.
16. HORROBIN DF. (1990). Essential fatty acids, lipid peroxidation, and cancer. In Omega-6 Essential Fatty Acids, Horrobin DF (ed.) pp. 351-378. Wiley-Liss: New York.
17. HUSSEY HJ AND TISDALE MK. (1994). Effect of polyunsaturated fatty acids on the growth of murine colon adenocarcinomas in vitro and in vivo. Br. J. Cancer, 70, 6–10.
18. ISOAI A, GOTO-TSUKAMOTO H, MURAKAMI K, AKEDO H AND HUMAGAI H. (1993). A potent anti-metastatic activity of tumor invasion-inhibiting factor-2 and albumin conjugateBiochem. Biophys. Res. Commun., 192, 7–14.
19. JIANG WG, LLOYDS D, PUNTIS MCA, NAKAMURA T AND HALLETT MB. (1993). Regulation of spreading and growth of human colon cancer cells by hepatocyte growth factorClin. Exp. Metastasis, 11, 235–242.
20. KARMALI RA, MARSH J AND FUCHS C. (1985). Effects of dietary enrichment with gamma linolenic acid upon growth of the R3230AC mammary adenocarcinomaJ. Nutr. Growth Cancer, 2, 41–51.
21. LIOTTA LA. (1987). Biochemical mechanisms of tumor invasion and metastasesClin. Physiol. Biochem., 5, 190–199.
22. McILLMURRAY M AND TURKIE W. (1987). Controlled trial of gamma linolenic acid in Dukes’ C colorectal cancerBr. Med. J., 294, 1260.
23. MIYAKE M, KOYAMA M, SENO M AND IKEYA MA. (1991). Identification of the motility-related protein (MRP-1), recognized by monoclonal antibody M31-15, which inhibits cell motilityJ. Exp. Med., 174, 1347–1354.
24. MOHLER JL, BROSKIE EN, RANPARIA DJ, SHARIEF Y, COLEMAN WB AND SMITH GJ. (1992). Cancer cell motility-inhibitory protein in the Dunning adenocarcinoma modelCancer Res., 52, 2349–2352.
25. NEWMAN MJ. (1990). Inhibition of carcinoma and melanoma cell growth by type 1 transforming growth factor beta is dependent on the presence of polyunsaturated fatty acidsProc. Natl Acad. Sci. USA, 87, 5543–5547.
26. OKA H, SHIOZAKI H, KOBAYASHI K, INOUE M, TAHARA H, KOBA-YASHI T, TAKATSUKA Y, MATRUYOSHI N, HIRANO S, TAKEICHI M AND MORI T. (1993). Expression of E-cadherin cell adhesion molecules in human breast cancer tissues and its relationship to metastasisCancer Res., 53, 1696–1701.
27. PARISH CR, JAKOBSEN KB AND COOMBE DR. (1992). A basement membrane permeability assay which correlates with the metastatic potential of tumour cellsInt. J. Cancer, 52, 378–383.
28. PRITCHARD GA AND MANSEL RE. (1990). The effects of essential fatty acids on the growth of breast cancer and melanoma. In Omega-6 Essential Fatty Acids, Horrobin DF (ed.) pp. 379-390. Wiley-Liss: New York.
29. RAMCHURREN N, BOTHA JH AND LEARY WP. (1985). An investigation into the effects of gamma linolenic acid on murine sarcoma M52BS. Afr. J. Sci., 81, 331.
30. ROSE DP, CONNOLLY JM AND MESCHTER CL. (1991). Effect of dietary fat on human breast cancer growth and lung metastasis in nude miceJ. Natl Cancer Inst., 83, 1491–1495.
31. ROSEN EM, MEROMSKY L, SETTER E, VINTER DW AND GOLDBERG I. (1990). Quantitation of cytokine-stimulated migration of endothelium and epithelium by a new assay using microcarrier beadsExp. Cell Res., 186, 22–31.
32. SCHIFFMANN E. (1990). Motility as a principal requirement for metastasisCancer Invest., 8, 673–674.
33. SCHIPPER JH, FRIXEN UH, BEHRENS J, UNGER A, JAHNKE D AND BIRCHMEIER W. (1991). E-cadherin expression in squamous cell carcinomas of head and neckCaner Res., 51, 6328–6337.
34. SHIOZAKI H, TAHARA H, OKA H, MIYATA M, KOBAYASHI K, TAMURA S, IIHARA K, DOKI Y, HIRANO S, TAKEICHI M AND MORI T. (1991). Expression of immunoreactive E-cadherin adhesion molecules in human cancersAm. J. Pathol., 139, 17–23.
35. TADA H, SHIHO O, KUROSHIMA K, KOYAMA M AND TSUKAMOTO K. (1986). An improved colorimetric assay for interleukin-2J. Immunol. Methods, 93, 157–165.
36. TAKEDA S, HORROBIN DF, MANKU M, SIM PG, ELLS G AND SIMMONS V. (1992). Lipid peroxidation in human breast cancer cells in response to gamma-linolenic acid and ironAnticancer Res., 12, 329–333.
37. TAKEDA S, SIM PG, HORROBIN DF, SANFORD T, CHISHOLM KA AND SIMMONS V. (1993). Mechanism of lipid peroxidation in cancer cells in response to gamma-linolenic acid (GLA) analyzed by Gc-Ms(I): conjugated dienes with peroxyl (or hydroperoxyl) groups and cell-killing effectsAnticancer Res., 13, 193–199.
38. TIWARI RK, MUKHOPADHYAY B, TELANG NT AND OSBORNE MP. (1991). Modulation of gene expression by selected fatty acids in human breast cancer cellsAnticancer Res., 11, 1383–1388.
39. VAN DER MERWE CF, BOOYENS J, KATZEFF IE. (1988). Oral gamma linolenic acid in 21 patients with unbeatable malignancyBr. J. Clin. Pract., 41, 907–915.
40. VAN DER MERWE CF, BOOYENS J, JOUBERT HF AND VAN DER MERWE CA. (1990). The effect of gamma-linolenic acid, an in vitro cytostatic substance contained in evening primrose oil, on primary liver cancer. A double-blind placebo controlled trialProstaglandins Leukotrienes Essential Fatty Acids, 40, 199–202.