Igf1 gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumin-containing neurons

Neuron

Volumn 14, Issue 4, 1995, Pages 717-730

  Beck, Klaus D ^a   Powell Braxtont, Lyn ^b   Widmer, Hans R ^a   Valverde, Janet ^a   Hefti, Franz ^a,c  

^a Department of Neuroscience Incorporated ^*  (United States)

^b GENENTECH INC   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALBINDIN; CALCIUM BINDING PROTEIN; CALRETININ; GLIAL FIBRILLARY ACIDIC PROTEIN; PARVALBUMIN; SOMATOMEDIN C;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTERIOR COMMISSURE; ARTICLE; ASTROCYTE; BRAIN SIZE; BRAIN WEIGHT; CAPSULA INTERNA; CELL COUNT; CENTRAL NERVOUS SYSTEM; CHOLINERGIC NERVE CELL; CONTROLLED STUDY; CORPUS CALLOSUM; CORPUS STRIATUM; DENTATE GYRUS; DOPAMINERGIC NERVE CELL; GENE DISRUPTION; GRANULE CELL; HIPPOCAMPUS; MOUSE; MYELINATION; NERVE FIBER; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; SPINAL CORD MOTONEURON; WHITE MATTER;

ANIMAL; ASTROCYTES; AXONS; BRAIN; CALCIUM-BINDING PROTEIN, VITAMIN D-DEPENDENT; CELL COUNT; CORPUS STRIATUM; GLIAL FIBRILLARY ACIDIC PROTEIN; HIPPOCAMPUS; INSULIN-LIKE GROWTH FACTOR I; MICE; MICE, INBRED C57BL; MUTATION; MYELIN SHEATH; NEURONS; ORGAN WEIGHT; PARVALBUMINS; SPINAL CORD; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0028941681     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/0896-6273(95)90216-3     Document Type: Article

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