Inhibition of Apoptosis during Development of Colorectal Cancer

Cancer Research

Volumn 55, Issue 9, 1995, Pages 1811-1816

  Bedi, Atul ^a   Akhtar, Adil J ^a   Barber, James P ^a   Hamilton, Stanley R ^a,b   Jones, Richard J ^a   Pasricha, Pankaj J ^b   Giardiello, Francis M ^b   Bedi, Gauri C ^b   Zehnbauer, Barbara A ^c  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

APOPTOSIS; ARTICLE; COLON CARCINOGENESIS; COLORECTAL CANCER; CONTROLLED STUDY; DNA DEGRADATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MALIGNANT TRANSFORMATION; PRIORITY JOURNAL;

ADENOMATOUS POLYPOSIS COLI; APOPTOSIS; CELL TRANSFORMATION, NEOPLASTIC; COLON; COLORECTAL NEOPLASMS; COMPARATIVE STUDY; EPITHELIAL CELLS; EPITHELIUM; HUMAN; INTESTINAL MUCOSA; MUTATION; RECTUM; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0028941441     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Fearon, E. R., and Vogelstein, B. A genetic model for colorectal tumorigenesis. Cell, 61: 759–767, 1990.
2. Deschner, E. E. Kinetics of normal, preneoplastic, and neoplastic colonic epithelium. In: M. P. Moyer and G. H. Poste (eds.), Colon Cancer Cells, pp. 41–61, San Diego: Academic Press, Inc., 1990.
3. Williams, G. T., and Smith, C. A. Molecular regulation of apoptosis: genetic controls on cell death. Cell, 74: 777–779, 1993.
4. Kerr, J. F. R., Wyllie, A. H., and Cunie, A. R. Apoptosis: basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer, 26: 239–257, 1972.
5. Gavrieli, Y., Sherman, Y., and Ben-Sasson, S. A. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol., 119: 493–501, 1992.
6. Bedi, A., Zehnbauer, B. A., Barber, J. P., Sharkis, S. J., and Jones, R. J. Inhibition of apoptosis by BCR-ABL in chronic myeloid leukemia. Blood, 83: 2038–2044, 1994.
7. Darzynkiewicz, Z., Bruno, S., Del Bino, G., Gorczyca, W., Hotz, M. A., Lassota, P., and Traganos, F. Features of apoptotic cells measured by flow cytometry. Cytometry, 13: 795–808, 1992.
8. Hockenbery, D. M., Zutter, M., Hickey, W., Nahm, M., and Korsmeyer, S. J. BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death. Proc. Natl. Acad. Sci. USA, 88: 6961–6965, 1991.
9. Kinzler, K. W., Nilbert, M. C., Su, L.-K., et al. Identification of FAP locus genes from chromosome 5q21. Science (Washington DC), 253: 661–664, 1991.
10. Powell, S. M., Zilz, N., Beazer-Barclay, Y., Bryan, T. M., Hamilton, S. R., Thi-bodeau, S. N., Vogelstein, B., and Kinzler, K. W. APC mutations occur early during colorectal tumorigenesis. Nature (Lond.), 359: 235–237, 1992.
11. Powell, S. M., Petersen, G. M., Krush, A. J., Booker, S., Jen, J., Giardiello, F. M., Hamilton, S. R., Vogelstein, B., and Kinzler, K. W. Molecular diagnosis of familial adenomatous polyposis. N. Engl. J. Med., 329: 1982–1987, 1993.
12. Korsmeyer, S. J. Bcl-2 initiates a new category of oncogenes: regulators of cell death. Blood, 80: 879–886, 1992.
13. Fisher, D. E. Apoptosis in cancer therapy: crossing the threshold. Cell, 78: 539–542, 1994.
14. Hague, A., Moorghen, M., Hicks, D., Chapman, M., and Paraskeva, C. BCL-2 expression in human colorectal adenomas and carinomas. Oncogene, 9: 3367–3370, 1994.
15. Su, L.-K., Vogelstein, B., and Kinzler, K. W. Association of the APC tumor suppressor protein with catenins. Science (Washington DC), 262: 1734–1737, 1993.
16. Baker, S. J., Fearon, E. R., Nigro, J. M., et al. Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas. Science (Washington DC), 244: 217–221, 1989.
17. Fearon, E. R., Cho, K. R., Nigro, J. M., Kern, S. E., Simons, J. W., Ruppert, J. M., Hamilton, S. R., Preisinger, A. C., Thomas, G., Kinzler, K. W., and Vogelstein, B. Identification of a chromosome 18q gene that is altered in colorectal cancers. Science (Washington DO, 247: 49–56, 1990.
18. Shaw, P., Bovey, R., Tardy, S., Sahli, R., Sordat, B., and Costa, J. Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line. Proc. Natl. Acad. Sci. USA, 89: 4495–4499, 1992.
19. Miyashita, T., Harigai, M., Hanada, M., and Reed, J. C. Identification of a p53-dependent negative response element in the bcl-2 gene. Cancer Res., 54: 3131–3135, 1994.
20. Miyashita, T., Krajewski, S., Krajewska, M., Wang, H. G., Iin, H. K., Liebermann, D. A., Hoffman, B., and Reed, J. C. Tumor suppressor p53 is a regulator of bcl-2 amd box gene expression in vitro and in vivo. Oncogene, 9; 1799–1805, 1994.