E5531, a pure endotoxin antagonist of high potency

Science

Volumn 268, Issue 5207, 1995, Pages 80-83

  Christ, William J ^a   Asano, Osamu ^a   Robidoux, Andrea L C ^a   Perez, Michel ^a   Wang, Yuan ^a   Dubuc, Gloria R ^a   Gavin, Wendy E ^a   Hawkins, Lynn D ^a   McGuinness, Pamela D ^a   Mullarkey, Maureen A ^a   Lewis, Michael D ^a   Kishi, Yoshito ^a   Kawata, Tsutomu ^a   Bristol, John R ^a   Rose, Jeffrey R ^a   Rossignol, Daniel P ^a   Kobayashi, Seiichi ^b   Hishinuma, Leharu ^b   Kimura, Akifumi ^b   Asakawa, Naoki ^b   Katayama, Kouichi ^b   Yamatsu, Isao ^b   more..

^a EISAI RESEARCH INSTITUTE   (United States)

^b EISAI CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTOXIN; LIPOPOLYSACCHARIDE; MEMBRANE PHOSPHOLIPID;

ARTICLE; BACTERIAL OUTER MEMBRANE; CONTROLLED STUDY; ESCHERICHIA COLI; GRAM NEGATIVE SEPSIS; INFLAMMATION; LETHALITY; MOLECULAR STABILITY; NONHUMAN; PRIORITY JOURNAL; RHODOBACTER CAPSULATUS; TOXIC SHOCK SYNDROME;

ANIMAL; BCG VACCINE; CYTOKINES; DRUG DESIGN; ENDOTOXINS; ESCHERICHIA COLI INFECTIONS; GRAM-NEGATIVE BACTERIA; HUMAN; IN VITRO; LIPID A; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MONOCYTES; MOXALACTAM; NITRIC OXIDE; RHODOBACTER CAPSULATUS; TUMOR NECROSIS FACTOR;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA; RHODOBACTER CAPSULATUS; RHODOPSEUDOMONAS;

EID: 0028941067     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.7701344     Document Type: Article

References (32)