Interleukin-6-induced serine phosphorylation of transcription factor APRF: evidence for a role in interleukin-6 target gene induction

FEBS Letters

Volumn 360, Issue 2, 1995, Pages 137-143

  Lütticken, Claudia ^a   Coffer, Paul ^b   Yuan, Juping ^a   Schwartz, Claudia ^a   Caldenhoven, Eric ^b   Schindler, Chris ^c   Kruijer, Wiebe ^d   Heinrich, Peter C ^a   Horn, Friedemann ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b HUBRECHT INSTITUTE   (Netherlands)

^c Division of Molecular Medicine College of Physicians and Surgeons Columbia University ^*  (United States)

^d UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

Acute phase response factor; Interleukin 6; Phosphorylation; Signal transduction; Stat; Transcription factor

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; ALPHA 2 MACROGLOBULIN; INTERCELLULAR ADHESION MOLECULE 1; RECOMBINANT INTERLEUKIN 6; TRANSCRIPTION FACTOR;

ARTICLE; GENE INDUCTION; HEPATOMA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ALPHA-MACROGLOBULINS; ANIMAL; BASE SEQUENCE; DNA; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; HUMAN; IN VITRO; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-6; ISOQUINOLINES; MICE; MOLECULAR SEQUENCE DATA; OLIGODEOXYRIBONUCLEOTIDES; PHOSPHOSERINE; PHOSPHOTYROSINE; PIPERAZINES; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS C-JUN; RATS; REGULATORY SEQUENCES, NUCLEIC ACID; RNA, MESSENGER; SIGNAL TRANSDUCTION; SUPPORT, NON-U.S. GOV'T; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED; TYROSINE;

EID: 0028938929     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-5793(95)00076-L     Document Type: Article

References (33)

1. Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor
2. A simple phase-extraction assay for chloramphenicol acyltransferase activity