Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: Tolerization of factor IX and vector antigens allows for long-term expression

Proceedings of the National Academy of Sciences of the United States of America

Volumn 92, Issue 5, 1995, Pages 1401-1405

  Dai, Yifan ^a   Schwarz, Edward M ^a   Gu, Danling ^b   Zhang, Wei Wei ^c   Sarvetnick, Nora ^b   Verma, Inder M ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 MICROGLOBULIN; BLOOD CLOTTING FACTOR 9; CD8 ANTIGEN; IMMUNOGLOBULIN MU CHAIN; NEUTRALIZING ANTIBODY; VIRUS ANTIBODY; VIRUS ANTIGEN;

ADENOVIRUS; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELLULAR IMMUNITY; CLONING VECTOR; CONTROLLED STUDY; GENE THERAPY; HUMORAL IMMUNITY; IMMUNOLOGICAL TOLERANCE; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; PROTEIN SECRETION; T LYMPHOCYTE; VIRUS RECOMBINANT;

ADENOVIRIDAE; ANIMAL; ANTIBODY FORMATION; ANTIGENS, VIRAL; CYCLOPHOSPHAMIDE; CYCLOSPORINE; DOGS; FACTOR IX; GENE THERAPY; GENETIC VECTORS; IMMUNE TOLERANCE; IMMUNITY, CELLULAR; MICE; MICE, KNOCKOUT; MICE, NUDE; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; VIRAL PROTEINS;

ADENOVIRIDAE; ANIMALIA; MUS MUSCULUS;

EID: 0028934815     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.92.5.1401     Document Type: Article

References (25)