Chronic hepatitis C virus infections: Predictive value of genotype and level of viraemia on disease progression and response to interferon α

Gut

Volumn 36, Issue 3, 1995, Pages 427-432

  Booth, J C L ^a   Foster, G R ^a   Kumar, U ^a   Galassini, R ^a   Goldin, R D ^a   Brown, J L ^a   Thomas, H C ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Hepatitis C virus genotype; Interferon ; Viraemia

Indexed keywords

ALPHA INTERFERON;

ARTICLE; CHRONIC HEPATITIS; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE COURSE; HEPATITIS C VIRUS; HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; VIREMIA;

EID: 0028934559     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.36.3.427     Document Type: Article

References (35)

1. Choo Q-L, Kuo G, Weiner A, Overby L, Bradley D, Houghton M. Isolation of a cDNA clone derived from a blood-borne viral hepatitis genome. Science 1989; 244: 359-62.
2. Choo Q-L, Richman K, Han J, Berger K, Lee C, Dong C, et al. The genetic organization and diversity of the hepatitis C virus. Proc Natl Acad Sci USA 1991; 88: 2451-5.
3. Houghton M, Choo Q, Kuo G. Chiron Corporation. European Patent App 88310922.5 1988; Publication number 0318216.
4. Stevens C, Taylor P, Pindyck J, Choo Q-L, Bradley D, Kuo G, et al. Epidemiology of hepatitis C virus. JAMA 1990; 263 (1): 49-53.
5. Alter MJ, Margolis HS, Krawczynski K, Judson FN, Mares A, Alexander WJ, et al. The natural history of community-acquired hepatitis C in the United States. N Engl J Med 1992; 327 (27): 1899-905.
6. Seeff LB, Buskell-Bales Z, Wright EC, Durako SJ, Alter HJ, Iber FL, et al. Long-term mortality after transfusion-associated non-A, non-B hepatitis. N Engl J Med 1992; 327 (27): 1906-11.
7. Hopf U, Moller B, Kuther D, Stemerowicz R, Lobeck H, Ludtke-Handjery A, et al. Long-term follow-up of posttransfusion and sporadic chronic hepatitis NANB and frequency of circulating antibodies to hepatitis C virus (HCV). J Hepatol 1990; 10: 69-76.
8. Realdi G, Alberti A, Rugge M, Rigoli A, Tremolada F, Schivazappa L, et al. Long-term follow-up of acute and chronic non-A, non-B post-transfusion hepatitis: evidence of progression to liver cirrhosis. Gut 1982; 23: 270-5.
9. Davis G, Balart L, Schiff E, Lindsay K, Bodenheimer H, Perrillo R, et al. Treatment of chronic hepatitis C with recombinant interferon alpha. N Engl J Med 1989; 321 (22): 1501-6.
10. Davis G. Recombinant α-interferon treatment of non-A, non-B (type C) hepatitis: review of studies and recommendations for treatment. J Hepatol 1990; 11: S72-7.
11. Di Bisceglie A, Martin P, Kassianidis C, Lisker-Melman M, Murray L, Waggoner J, et al. Recombinant interferon alfa therapy for chronic hepatitis C. A randomized, double-blind, placebo-controlled trial. N Engl J Med 1989; 321 (22): 1506-10.
12. Di Bisceglie A, Hoofnagle J. Therapy of chronic hepatitis C with α-Interferon: The answer? or more questions? Hepatology, 1991; 13 (3): 601-3.
13. Jacyna M, Brooks M, Loke R, Main J, Murray-Lyon I, Thomas H. Randomised controlled trial of interferon alpha (lymphoblastoid interferon) in chronic non-A, non-B hepatitis. BMJ 1989; 298: 80-2.
14. Shindo M, Di Bisceglie AM, Hoofnagle JH. Long-term follow-up of patients with chronic hepatitis C treated with α-interferon. Hepatology 1992; 15 (6): 1013-6.
15. Cha T-A, Beall E, Irvine B, Kolberg J, Chien D, Kuo G, Urdea MS. At least five related, but distinct, hepatitis C viral genotypes exist. Proc Natl Acad Sci USA 1992; 89: 7144-8.
16. Chan S-W, McOmish F, Holmes EC, Dow B, Peutherer JF, Follett E, et al. Analysis of a new hepatitis C virus type and its phylogenetic relationship to existing variants. J Gen Virol 1992; 73: 1131-41.
17. Simmonds P, McOmish F, Yap PL, Chan S-W, Lin CK, Dusheiko G, et al. Sequence variability in the 5′ noncoding region of hepatitis C virus: identification of a new virus type and restrictions on sequence diversity. J Gen Virol 1993; 74: 661-8.
18. Okamoto H, Sugiyama Y, Okada S, Kurai K, Akahane Y, Sugai Y, et al. Typing hepatitis C virus by polymerase chain reaction with type-specific primers: application to clinical surveys and tracing infectious sources. J Gen Virol 1992; 73: 673-9.
19. Enomoto N, Takada A, Nakao T, Date T. There are two major types of hepatitis C virus in Japan. Biochem Biophys Res Commun 1990; 170 (3): 1021-5.
20. Houghton M, Weiner A, Han J, Kuo G, Choo Q-L. Molecular biology of the hepatitis C viruses: implications for diagnosis, development and control of viral disease. Hepatology 1991; 14 (2): 381-8.
21. Karo N, Hijikata M, Ootsuyama Y, Nakagawa M, Ohkoshi S, Sugimura T, et al. Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis. Proc Natl Acad Sci USA 1990; 87: 9524-8.
22. Dusheiko G, Simmonds P. Sequence variability of hepatitis C virus and its clinical revelance. Journal of Viral Hepatitis 1994; 1: 3-15.
23. Chemello L, Alberti A, Rose K, Simmonds P. Hepatitis C serotype and response to interferon therapy. N Engl J Med 1994; 330: 143.
24. Kanai K, Kako M, Okamoto H. HCV genotypes in chronic hepatitis C and response to interferon. Lancet 1992; 339: 1543.
25. Yoshioka K, Kakumu S, Wakita T, Ishikawa T, Itoh Y, Takayanagi M, et al. Detection of hepatitis C virus by polymerase chain reaction and response to interferon-α therapy: relationship to genotypes of hepatitis C virus. Hepatology 1992; 16: 293-9.
26. Kobayashi Y, Watanabe S, Konishi M, Yokoi M, Kakehashi R, et al. Quantitation and typing of serum hepatitis C virus RNA in patients with chronic hepatitis C treated with interferon-β. Hepatology 1993; 18 (6): 1319-25.
27. Pozzato G, Moretti M, Franzin F, Crocy L, Tiribelli C, Masayu T, et al. Severity of liver disease with different HCV clones. Lancet 1991; 338: 509.
28. Takada N, Takase S, Enomoto N, Takada A, Date T. Clinical backgrounds of the patients having different types of hepatitis C virus genomes. J Hepatol 1992; 14: 35-40.
29. McOmish F, Chan S-W, Dow BC, Gillon J, Frame WD, Crawford RJ, et al. Detection of three types of hepatitis C virus in blood donors: investigation of type-specific differences in serologic reactivity and rate of alanine aminotransferase abnormalities. Transfusion 1993; 33 (1): 7-13.
30. Knodell R, Ishak K, Black W, Chen T, Craig R, Kaplowitz N, et al. Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis. Hepatology 1981; 1: 431-5.
31. Dourakis S, Brown J, Kumar U, Karayiannis P, Kernoff P, Chiba J, et al. Serological response and detection of viraemia in acute hepatitis C virus infection. J Hepatol 1992; 14: 370-6.
32. Kumar U, Thomas H, Monjardino J. Serum HCV RNA levels in chronic HCV hepatitis measured by quantitative PCR assay; correlation with serum AST. J Virol Methods 1994; 47: 95-102.
33. Dusheiko G, Schmilovitz-Weiss H, Brown D, McOmish F, Yap P-L, Sherlock S, et al. Hepatitis C genotypes: An investigation into type-specific differences in geographic origin and disease. Hepatology 1994; 19 (1): 13-8.
34. Gunji T, Kato N, Mori S, Ootsuyama Y, Hijikata M, Imawari M, et al. Correlation between serum level of hepatitis C virus RNA and disease activities in acute and chronic hepatitis C. Int J Cancer 1992; 52: 726-30.
35. Hagiwara H, Hayashi N, Mita E, Naito M, Kasahara A, Fusamoto H, et al. Quantitation of hepatitis C virus RNA in serum of asymptomatic blood donors and patients with type C chronic liver disease. Hepatology 1993; 17 (4): 545-50.