Determination of 8-hydroxydeoxyguanosine by an immunoaffinity chromatography-monoclonal antibody-based ELISA

Free Radical Biology and Medicine

Volumn 18, Issue 6, 1995, Pages 1023-1032

  Yin, Baoyun ^a   Whyatt, Robin M ^a   Perera, Frederica P ^a   Randall, Mary C ^a   Cooper, Thomas B ^b   Santella, Regina M ^a  

^a Cancer Center/Division of Environmental Sciences School of Public Health Columbia University ^*  (United States)

^b NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

Author keywords

8 Hydroxydeoxyguanosine; Electrochemical detection; ELISA; Free radicals; Immunoaffinity chromatography

Indexed keywords

8 HYDROXYDEOXYGUANOSINE;

ARTICLE; CONTROLLED STUDY; DNA DAMAGE; ELECTROCHEMICAL DETECTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; INTERMETHOD COMPARISON; METHODOLOGY; PLACENTA; PRIORITY JOURNAL; QUANTITATIVE ASSAY; SMOKING;

ANIMAL; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; BINDING, COMPETITIVE; CHROMATOGRAPHY, AFFINITY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYGUANOSINE; DNA; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; MICE; MICE, INBRED BALB C; PLACENTA; PREGNANCY; SMOKING; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0028933255     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/0891-5849(95)00003-G     Document Type: Article

References (46)

1. Molecular mechanisms of oxygen radical carcinogenesis and mutagenesis: The role of DNA base damage
2. DNA damage by oxygen-derived species
3. The toxicology of molecular oxygen
4. Oxidative damage to DNA: Relation to species metabolic rate and life span
5. Genetic toxicology of oxygen
6. Endogenous oxidative DNA damage, aging, and cancer
7. Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues
8. Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG
9. Mechanistic studies of ionizing radiation and oxidative mutagenesis: Genetic effects of a single 8-hydroxyguanine (7-hydro8-oxoguanine) residue inserted at a unique site in a viral genome
10. 8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G-T and A-C substitutions
11. Hydroxylation of guanine in nucleosides and DNA at the C-8 position by heated glucose and oxygen radical-forming agents
12. Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen radicals and evidence for its repair
13. Formation of 8-hydroxydeoxyguanosine, hydroxyl free radical adduct of DNA in granulocytes exposed to the tumor promoter, tetradeconylphorbolacetate
14. Cigarette smoke-induced DNA-damage: Role of hydroquinone and catechol in the formation of the oxidative DNA-adduct, 8-hydroxydeoxyguanosine
15. Formation of 8-hydroxydeoxyguanosine by asbestos and man made mineral fibres
16. Oxidative DNA and RNA damage in the livers of Sprague-Dawley rats treated with the hepatocarcinogen 2-nitropropane
17. Elevated 8-hydroxydeoxy-guanosine levels in DNA of diethylstilbestroi-treated Syrian hamsters: Covalent DNA damage by free radicals generated by redox cycling of diethylstilbestrol
18. Relation of 8-hydroxydeoxyguanosine formation in rat kidney to lipid peroxidation, glutathione level and relative organ weight after a single administration of potassium bromate
19. Short-term exposure to the peroxisome proliferators, perfluorooctanoic acid and perfluorodecanoic acid, causes significant increase of 8-hydroxydeoxyguanosine in liver DNA of rats
20. An endonuclease activity of Escherichia coli that specifically removes 8-hydroxyguanine residues from DNA
21. An endonuclease activity in human polymorphonuclear neutrophils that removes 8-hydroxyguanine residues from DNA
22. A repair system for 8-oxo-7,8-dihydrodeoxyguanine
23. Hydroxyl free radical adduct of deoxyguanosine: Sensitive detection and mechanisms of formation
24. Formation of an 8-hydroxyguanine moiety in deoxyribonucleic acid on γ-irradiation in aqueous solution
25. Detection of 8-hydroxyguanine in small amounts of DNA by 32p postlabeling
26. Immunoaffinity isolation of urinary 8-hydroxy-2′-deoxyguanosine and 8-hydroxyguanine and quantitation of 8-hydroxy-2′-deoxyguanosine in DNA by polyclonal antibodies
27. Quantitative immunoanalysis of promutagenic 8-hydroxy-2'deoxyguanosine in oxidized DNA
28. Urinary 8-hydroxy-2′-deoxyguanosine as a biological marker of in vivo oxidative DNA damage
29. Cigarette smoking induces formation of 8-hydroxydeoxyguanosine, one of the oxidative DNA damages in human peripheral leukocytes
30. Detection and quantitation of 8-hydroxydeoxyguanosine adducts in peripheral blood of people exposed to ionizing radiation
31. Major alterations in the nucleotide structure of DNA in cancer of the female breast
32. DNA base modifications in chromatin of human cancerous tissues
33. Elimination from the body of tobacco products by smokers and passive smokers
34. Misclassification of smoking status in the CARDIA study: A comparison of self-report with serum cotinine levels
35. In vivo oxidative DNA damage: Measurement of 8-hydroxy-2′-deoxyguanosine in DNA and urine by high-performance liquid chromatography with electrochemical detection
36. Hydroxylation of deoxyguanosine at the C-8 position by ascorbic acid and other reducing agents
37. CYPIA1 mRNA levels in placental tissue as a biomarker of environmental exposure
38. Heavy smokers, smoking cessation, and clonidine
39. Biomarkers of environmental tobacco smoke in preschool children and their mothers
40. Assays of oxidative DNA damage biomarkers 8-oxo-2′-deoxyguanosine and 8-oxoguanine in nuclear DNA and biological fluids by high-performance liquid chromatography with electrochemical detection
41. Assays of exised oxidative DNA lesions: Isolation of 8-oxoguanine and its nucleoside derivatives from biological fluids with a monoclonal antibody column
42. Antisera specific for carcinogen-DNA adducts and carcinogen-modified DNA: Applications for detection of xenobiotics in biological samples
43. Immunoaffinity purification combined with 32p-postlabelling for the detection of O6-methylguanine in DNA from human tissues
44. 8-Hydroxyguanine, a DNA adduct formed by oxygen radicals: Its implication on oxygen radical-involved mutagenesis/carcinogenesis
45. Ascorbic acid protects against endogenous oxidative DNA damage in human sperm
46. Effect of physical exercise on the content of 8-hydroxyguanosine in nuclear DNA prepared from human lymphocytes