Comparison of iodine-123 labelled 2β-carbomethoxy-3β-(4-iodophenyl)tropane and 2β-carbomethoxy-3β-(4-iodophenyl)-N-(3-fluoropropyl)nortropane for imaging of the dopamine transporter in the living human brain

European Journal of Nuclear Medicine

Volumn 22, Issue 4, 1995, Pages 356-360

  Kuikka, Jyrki T ^a   Bergström, Kim A ^a   Ahonen, Aapo ^b   Hiltunen, Jukka ^c   Haukka, Jarmo ^c   Länsimiese, Esko ^a   Wang, Shaoyin ^d   Neumeyer, John L ^d  

^a KUOPIO UNIVERSITY HOSPITAL   (Finland)

^b OULU UNIVERSITY HOSPITAL   (Finland)

^c MAP Medical Technologies Oy   (Finland)

^d Research Biochemicals International   (United States)

Author keywords

2 Carbomethoxy 3 (4 iodophenyl) N (3 fluoropropyl)nortropane; 2 Carbomethoxy 3 (4 iodophenyl)tropane; Dopamine transporter; Single photon emission tomography

Indexed keywords

2BETA CARBOMETHOXY 3BETA (4 IODOPHENYL) N (3 FLUOROPROPYL)NORTROPANE; 3BETA (4 IODOPHENYL) 2BETA TROPANECARBOXYLIC ACID METHYL ESTER; DOPAMINE; IODINE 123; TRACER; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BASAL GANGLION; BRAIN; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC VALUE; DOPAMINERGIC TRANSMISSION; HUMAN; HUMAN EXPERIMENT; IMAGE QUALITY; MALE; NEUROPSYCHIATRY; NORMAL HUMAN; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

BRAIN; BRAIN CHEMISTRY; CARRIER PROTEINS; COCAINE; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; HUMANS; IODINE RADIOISOTOPES; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MIDDLE AGED; NERVE TISSUE PROTEINS; PILOT PROJECTS; TIME FACTORS; TISSUE DISTRIBUTION; TROPANES;

EID: 0028933124     PISSN: 03406997     EISSN: 16197089     Source Type: Journal    
DOI: 10.1007/BF00941854     Document Type: Article

References (12)

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7. In vivo characterization of 3-iodo-6-methoxybenzamide [123I] in humans
8. The dosimetry of iodine-123 labelled 2β-carbomethoxy-3β(4-iodophenyl) tropane
9. Graphical, kinetic, and equilibrium analyses of in vivo [123I]β-CIT binding to dopamine transporters in healthy human subjects
10. Single-photon emission tomography imaging of dopamine terminal innervation: a potential clinical tool in Parkinson's disease