The immunogenicity of MUC1 peptides and fusion protein

Cancer Letters

Volumn 90, Issue 1, 1995, Pages 21-26

  Apostolopoulos, V ^a   Pietersz, G A ^a   Xing, P X ^a   Lees, C J ^a   Michael, M ^b   Bishop, J ^b   McKenzie, I F C ^a  

^a AUSTIN RESEARCH INSTITUTE   (Australia)

^b PETER MACCALLUM CANCER CENTRE   (Australia)

Author keywords

Fusion protein; Mannan; MUC1 peptides; Vaccine

Indexed keywords

CANCER VACCINE; DIPHTHERIA TOXIN; HYBRID PROTEIN; MANNAN; MILK FAT; MUCIN; PEPTIDE;

ANTIBODY RESPONSE; BREAST CANCER; CANCER IMMUNIZATION; CANCER IMMUNOTHERAPY; CELL STRAIN 3T3; CELLULAR IMMUNITY; CLINICAL ARTICLE; CLINICAL TRIAL; CONFERENCE PAPER; CYTOTOXIC T LYMPHOCYTE; DELAYED HYPERSENSITIVITY; FEMALE; HUMAN; IMMUNE RESPONSE; IMMUNOGENICITY; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; TUMOR REJECTION; VARIABLE NUMBER OF TANDEM REPEAT;

ANIMAL; ANTIGENS, NEOPLASM; BREAST NEOPLASMS; CA-15-3 ANTIGEN; HUMAN; MEMBRANE GLYCOPROTEINS; MICE; MUCINS; NEOPLASM PROTEINS; RECOMBINANT FUSION PROTEINS;

STEATOMYS PRATENSIS;

EID: 0028932307     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3835(94)03673-7     Document Type: Article

References (22)

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15. Adenocarcinoma reactive cytotoxic T lymphocytes recognize an epitope present on the protein core of epithelial mucin molecules
16. Cytotoxic T cells from ovarian malignant tumors can recognize polymorphic epithelial mucin core peptides
17. Tumor-specific cytotoxic T lymphocytes from patients with breast and pancreatic adenocarcinoma recognize EBV-immortalized B cells transfected with polymorphic epithelial mucin cDNA
18. CD8 cells play a critical role in delayed type hypersensitivity to intact cryptococcus neoformans
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22. Immune responses of mice and human breast cancer patients following immunization with synthetic sialyl-Tn conjugated to KLH plus Detox adjuvant