Loss of heterozygosity in ductal carcinoma in situ of the breast

The Journal of Pathology

Volumn 175, Issue 2, 1995, Pages 195-201

  Stratton, Michael R ^a   Collins, Nadine ^a   Lakhani, Sunil R ^a   Sloane, John P ^a  

^a ROYAL MARSDEN HOSPITAL   (United Kingdom)

Author keywords

Breast cancer; ductal carcinoma in situ; loss of heterozygosity

Indexed keywords

ARTICLE; BREAST CARCINOMA; CARCINOMA IN SITU; CONTROLLED STUDY; FEMALE; HETEROZYGOSITY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

BREAST NEOPLASMS; CARCINOMA IN SITU; CARCINOMA, INFILTRATING DUCT; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 16; CHROMOSOMES, HUMAN, PAIR 17; CHROMOSOMES, HUMAN, PAIR 7; FEMALE; HETEROZYGOTE; HUMAN; NEOPLASM INVASIVENESS; SUPPORT, NON-U.S. GOV'T;

EID: 0028931870     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.1711750207     Document Type: Article

References (24)

1. Reduction to homozygosity of genes on chromosome 11 in human breast neoplasia
2. Presence of two members of c‐ erbA receptor gene family (c‐ erbAb and c‐ arbA2) in smallest region of somatic homozygosity on chromosome 3p21‐p25 in human breast carcinoma
3. Loss of heterozygosity on chromosome 7q and aggressive breast cancer
4. Loss of heterozygosity on chromosome lq in human breast cancer
5. Evidence implicating at least two genes on chromosome 17p in breast carcinogenesis
6. Allele loss patterns on chromosome 17q in 109 breast carcinomas indicate at least two distinct target regions
7. Loss of heterozygosity on chromosomes 17 and 18 in breast carcinoma: two additional regions identified
8. Somatic genetic changes on chromosome 18 in breast carcinomas: is the DCC gene involved?
9. Allelotype of human breast carcinoma: a second major site for loss of heterozygosity is on chromosome 6q
10. The locus of the polmorphic epithelial mucin (PEM) tumour antigen on chromosome 1q21 shows a high frequency of alteration in primary human breast tumours
11. Deletions on chromosome 16 in primary familial breast carcinomas are associated with development of distant metastases
12. Allele loss on short arm of chromosome 17 in breast cancer
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14. Structural rearrangements of the retinoblastoma gene in human breast carcinoma
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16. A genetic model for colorectal tumorigenesis
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19. p53 protein expression in mammary ductal carcinoma in situ: relationship to immunohistochemical expression of estrogen reeptor and c‐ erbB‐2 protein
20. p53 mutations and c‐ erbB‐2 amplification in intraductal and invasive breast carcinomas of high histologic grade
21. Linkage analysis of early onset familial breast cancer to chromosome 17q 12–;21
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24. Allelic loss on a chromosome 17 in ductal carcinoma in situ of the breast