Assessment of numeric abnormalities of X, Y, 18, and 16 chromosomes in preimplantation human embryos before transfer

American Journal of Obstetrics and Gynecology

Volumn 172, Issue 4, 1995, Pages 1191-1201

  Munné, Santiago ^a   Sultan, Khalid M ^a   Weier, Heinz Ulrich ^b,c   Grifo, James A ^a   Cohen, Jacques ^a   Rosenwaks, Zev ^a  

^a WEILL CORNELL MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

fluorescence in situ hybridization; in vitro fertilization; Monosomy; mosaicism; preimplantation genetic diagnosis

Indexed keywords

ANEUPLOIDY; CHROMOSOME ABERRATION; CLINICAL TRIAL; CONFERENCE PAPER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; EMBRYO; EMBRYO TRANSFER; FERTILIZATION IN VITRO; FLUORESCENCE; GENETIC SCREENING; HUMAN; HUMAN TISSUE; PREIMPLANTATION EMBRYO; PRIORITY JOURNAL; SAFETY;

EID: 0028931223     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/0002-9378(95)91479-X     Document Type: Article

References (53)

1. Frequency of implantation and early pregnancy loss in natural cycles
2. Chromosome analysis of spontaneous abortions after IVF: a European survey
3. Life and death before birth [Editorial]
4. Incidence of early loss of pregnancy
5. Are clinical and biological IVF parameters correlated with chromosomal disorders in early life: a multicentric study
6. Chromosome abnormalities in human arrested preimplantation embryos: a multiple-probe FISH study
7. Direct assessment of the rate of chromosomal abnormalities in grade IV human embryos produced by in-vitro fertilization procedure
8. Incidence of numerical chromosome abnormalities in human pregnancy estimated from induced and spontaneous abortion data
9. Maternal age-specific rates of numerical chromosome abnormalities with special reference to trisomy
10. Cytogenetic abnormalities in spontaneous abortions of recognized conceptions
11. Reversing the natural decline in human fertility: an extended clinical trial of oocyte donation to women of advanced reproductive age
12. Three color fluorescence in-situ hybridization for the simultaneous detection of multiple nucleic acid sequences
13. Multiple colors by fluorescence in-situ hybridization using ratio-labelled DNA probes create a molecular karyotype
14. Simultaneous visualization of seven different DNA probes by in-situ hybridization using combinational fluorescence and digital imaging microscopy
15. Dual fluorescent in-situ hybridization for simultaneous detection of X and Y chromosome-specific probes for the sexing of human preimplantation embryonic nuclei
16. Detection of aneuploidy and chromosomal mosaicism in human embryos during preimplantation sex determination by fluorescence in situ hybridization (FISH)
17. A fast and efficient method for simultaneous X and Y in-situ hybridization of human blastomeres
18. Sex determination of human embryos using the polymerase chain reaction and confirmation by fluorescence in situ hybridization
19. Diagnosis of major chromosome aneuploidies in human preimplantation embryos
20. Molecular studies of nondisjunction in trisomy 16
21. Assisted fertilization by zona drilling: a mouse model for correction of oligospermia
22. Healthy deliveries from biopsied human embryos
23. Ongoing pregnancy in a hemophilia carrier by embryo biopsy and simultaneous amplification of X and Y chromosome specific DNA from single blastomeres
24. An air drying method for chromosome preparations from mouse eggs
25. Cytogenetic analysis by in-situ hybridization with fluorescently labeled nucleic acid probes
26. A simple method of reducing the fading of immunofluorescence during microscopy
27. In-situ hybridization as a tool to study numerical chromosome aberrations in solid bladder tumors
28. Preimplantation diagnosis of aneuploidy using fluorescent in-situ hybridization: evaluation using a chromosome 18-specific probe
29. Human preimplantation development in-vitro is not adversely affected by biopsy at the 8-cell stage
30. Cytogeneticsof human oocytes, zygotes, and embryos after in-vitro fertilization
31. Chromosome investigations in early life: human preimplantation embryos
32. Preimplantation genetics: chromosomes of fragmented human embryos
33. Assessment of ploidy in human morulae and blastocysts using co-culture and fluorescent in-situ hybridization
34. Polyploid cells in blastocysts and early fetuses from Australian Merino sheep
35. A comparison of the chromosome complement of inner cell mass and trophoblast cells in day-10 pig embryos
36. Chromosomal analysi sof 159 bovine embryos collected 12 to 18 days after estrus
37. Production and properties of mouse trisomy 15 diploid chimeras
38. Production of viable adult trisomy 17 diploid mouse chimeras
39. Successful single-cell biopsy and cryopreservation of preimplantation mouse embryos
40. Pregnancy after the replacement of a frozen-thawed embryo with <50% intact blastomeres
41. Unsuitability of multinucleated human blastomeres for preimplantation genetic diagnosis
42. A cytogenetic study of 1000 spontaneous abortuses
43. Chromosome abnormalities in human embryos after in-vitro fertilization
44. The early lethality of autosomal monosomy in the mouse
45. The effect of maternal age on the frequency of trisomy: change in meiosis or in utero selection?
46. Early embryonic mortality in women
47. Incidence of early loss of pregnancy
48. A cytogenetic study of 1000 spontaneous abortions
49. Incidence of numerical chromosome anomalies in human pregnancy: estimation from induced and spontaneous abortion data
50. Frequency and distribution of aneuploidy in human female gametes
51. Differential distribution of aneuploidy in human gametes according to their sex
52. Paternal contribution to embryonic death