Synthesis of a diepitope multiple antigen peptide containing sequences from two malaria antigens using Fmoc chemistry

Journal of Immunological Methods

Volumn 179, Issue 2, 1995, Pages 269-275

  Ahlborg, Niklas ^a  

^a STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

Fmoc chemistry; Multiple antigen peptide; Peptide synthesis

Indexed keywords

PARASITE ANTIGEN; SYNTHETIC PEPTIDE;

ARTICLE; CHEMISTRY; ENZYME LINKED IMMUNOSORBENT ASSAY; PEPTIDE SYNTHESIS; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMAL; ANTIBODIES, PROTOZOAN; ANTIGENS, PROTOZOAN; EPITOPES; FLUORENES; LYSINE; MICE; MOLECULAR SEQUENCE DATA; PEPTIDES; PLASMODIUM FALCIPARUM; SUPPORT, NON-U.S. GOV'T;

PLASMODIUM FALCIPARUM;

EID: 0028928920     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/0022-1759(94)00328-T     Document Type: Article

References (13)

1. Definition of the epitope recognized by the Plasmodium falciparum-reactive human monoclonal antibody 33G2
2. Novel version of multiple antigenic peptide allowing incorporation on a cysteine functionalized lysine tree
3. A novel lysine-protecting procedure for continous flow solid phase synthesis of branched peptides
4. Immunogenic properties of multiple antigen peptide systems containing defined T and B epitopes
5. Chemically unambiguous peptide immunogen: Preparation, orientation and antigenicity of purified peptide conjugated to the multiple antigen peptide system
6. Immunogenicity of multiple antigen peptides (MAP) containing T and B epitopes of the repeat region of the P. falciparum circumsporozoite protein
7. Circumsporozoite proteins of human malaria parasites Plasmodium falciparum and Plasmodium vivax
8. Rapid ‘tea-bag’ synthesis using 9-fluorenylmethoxycarbonyl (Fmoc) protected amino acids applied for antigenic mapping of viral proteins
9. Synthetic peptide vaccine design: synthesis and properties of a high-density multiple antigenic peptide system
10. Vaccine enginering: enhancement of immunogenicity of synthetic peptide vaccines related to hepatitis in chemically defined models consisting of T- and B-cell epitopes
11. Multiple antigen peptide. A novel approach to increase detection sensitivity of synthetic peptides in solid-phase immunoassays
12. Incorporation of T and B epitopes of the circumsporozoite protein in a chemically defined synthetic vaccine against malaria
13. Human monoclonal antibodies to Pf155, a major antigen of malaria parasite Plasmodium falciparum