Regulation of potassium channels by nonsedating antihistamines

Circulation

Volumn 91, Issue 8, 1995, Pages 2220-2225

  Berul, Charles I ^a   Morad, Martin ^b,c  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^c GEORGETOWN UNIVERSITY   (United States)

Author keywords

antihistamines; potassium; repolarization

Indexed keywords

ASTEMIZOLE; EGTAZIC ACID; HISTAMINE H1 RECEPTOR ANTAGONIST; POTASSIUM CHANNEL; TERFENADINE;

ANIMAL CELL; ARRHYTHMOGENESIS; ARTICLE; DOSE RESPONSE; GUINEA PIG; HEART MUSCLE CELL; HEART VENTRICLE; MALE; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; PRIORITY JOURNAL; RAT;

EID: 0028927451     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.91.8.2220     Document Type: Article

References (43)

1. 1-receptor-antagonist drugs. N Engl J Med. 1994;330:1663-1670.
2. 1-receptor antagonists. Clin Phamacol. 1989;8:331-344.
3. 1 antihistamines: treatment of urticaria and other clinical problems. Dermatol Clin. 1993;11: 87-94.
4. Craft TM. Torsades de pointes after astemizole overdose. Br Med J. 1985;292:660.
5. Snook J, Boothman-Burrell D, Watkins J, Colin-Jones D. Torsades de pointes ventricular tachycardia associated with astemizole overdose. Br J Clin Pract. 1988;42:257-258.
6. Leor J, Harman M, Rabinowitz B, Mozes B. Giant U waves and associated ventricular tachycardia complicating astemizole overdose. Am J Med. 1991;91:94-97.
7. Bishop RO, Gaudry PL. Prolonged Q-T interval following astemizole overdose. Arch Emerg Med. 1989;6:63-65.
8. Simons FER, Kesselman MS, Giddins NG, Pelech AN, Simons KJ. Astemizole-induced torsade de pointes. Lancet. 1988;2:624. Letter.
9. Hoppu K, Tikanoja T, Tapanainen P, Remes M, SaarenpaaHeikkila O, Kouvalainen K. Accidental astemizole overdose in young children. Lancet. 1991;338:538-539.
10. Tobin JR, Doyle TP, Ackerman A, Brenner JI. Astemizole-induced cardiac conduction disturbances in a child. JAMA. 1991;266: 2737-2740.
11. Wiley JF, Gelber ML, Henretig FM, Wiley CC, Sandhu S, Loiselle J. Cardiotoxic effects of astemizole overdose in children. J Pediatr. 1992;120:799-802.
12. Davies AJ, Harindra V, McEwan A, Ghose RR. Cardiotoxic effect with convulsions in terfenadine overdose. Br Med J. 1989;298:325.
13. Monahan BP, Ferguson CL, Killeavy ES, Lloyd BK, Troy J, Cantilena LR. Torsades de pointes occurring in association with terfenadine use. JAMA. 1990;264:2788-2790.
14. Kemp JP. Antihistamines: is there anything safe to prescribe? Ann Allergy. 1992;69:276-280.
15. Safety of terfenadine and astemizole. Med Lett Drugs Ther. 1992;34:9-10.
16. Honig PK, Wortham DC, Zamani K, Conner DP, Mullin JC, Cantilena LR. Terfenadine-ketoconazole interaction. JAMA. 1993;269: 1513-1518.
17. Honig PK, Woosley RL, Zamani K, Conner DP, Cantilena LR. Changes in the pharmacokinetics and electrocardiographic pharmacodynamics of terfenadine with concomitant administration of erythromycin. Clin Pharmacol Ther. 1992;52:231-238.
18. Nattel S, Ranger S, Talajic M, Lemery R, Roy D. Erythromycininduced long QT syndrome: concordance with quinidine and underlying cellular electrophysiologic mechanism. Am J Med. 1990;89:235-238.
19. Wolf AA, Levi R. Histamine and cardiac arrhythmias. Circ Res. 1986;58:1-16.
20. Verma SC, McNeill JH. Cardiac histamine receptors: differences between left and right atria and right ventricle. J Pharmacol Exp Ther. 1977;200:352-362.
21. Mitra R, Morad M. A uniform enzymatic method for the dissociation of myocytes from heart and stomach of vertebrates. Am J Physiol. 1985;249:H1056-H1060.
22. Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch. 1981;391: 85-100.
23. + dependence. J Physiol. 1991;435:395-420.
24. Yazawa K, Kameyama M. Mechanism of receptor-mediated modulation of the delayed outward potassium current in guinea pig ventricular myocytes. J Physiol. 1990;421:135-150.
25. Walsh KB, Begenisich TB, Kass RS. Beta-adrenergic modulation of cardiac ion channels: differential temperature sensitivity of potassium and calcium currents. J Gen Physiol. 1989;93:841-854.
26. K by protein kinases A and C. Am J Physiol. 1991;261:C1081-C1090.
27. Woosley RL, Chen Y, Freiman JP, Gillis RA. Mechanism of the cardiotoxic actions of terfenadine. JAMA. 1993;269:1532-1536.
28. + channel cloned from human heart. Mol Pharmacol. 1993;44:1240-1245.
29. Giles WR, Imaizuma Y. Comparison of potassium currents in rabbit atrial and ventricular cells. J Physiol. 1988;405:123-146.
30. + current in cardiac myocytes by dofetilide. J Pharmacol Exp Ther. 1992;262:809-817.
31. Hume JR, Umehara A. Ionic basis of the different action potential configurations of single guinea pig atrial and ventricular myocytes. J Physiol. 1985;368:525-544.
32. K, by flecainide and E-4031 in cat ventricular myocytes. Circulation. 1990;82:289-293.
33. Doerr T, Denger R, Doerr A, Trautwein W. Ionic currents contributing to the action potential in single ventricular myocytes of the guinea pig studied with the action potential clamp. Pflugers Arch. 1990;416:230-237.
34. DeFelice LJ, Goolsby WN, Mazzanti M. Potassium channels and the repolarization of cardiac cells. Ann NY Acad Sci. 1990;588: 174-184.
35. Martin CL, Chinn K. Contribution of delayed rectifier and inward rectifier to repolarization of the action potential: pharmacologic separation. J Cardiovasc Pharmacol. 1992;19:830-837.
36. Harvey RD, TenEick RE. Characterization of the inward-rectifying potassium current in cat ventricular myocytes. J Gen Physiol. 1988;91:593-615.
37. + current during the action potential of guinea pig ventricular myocytes. Biophys J. 1991;60:1534-1539.
38. Escande D, Coulombe A, Faivre JF, Deroubaix E, Coraboeuf E. Two types of transient outward currents in adult human atrial cells. Am J Physiol. 1987;252:H142-H148.
39. Josephson IR, Sanchez-Chapula J, Brown AM. Early outward current in rat single ventricular cells. Circ Res. 1984;54:157-162.
40. Furukawa T, Kimura S, Furukawa N, Bassett AL, Myerburg RJ. Potassium rectifier currents differ in myocytes of endocardial and epicardial origin. Circ Res. 1992;70:91-103.
41. Komeichi K, Tohse N, Nakaya H, Shimizu M, Zhu M-Y, Kanno M. Effects of N-acetylprocainamide and sotalol on ion currents in isolated guinea-pig ventricular myocytes. Eur J Pharmacol. 1990;187:313-322.
42. + currents in mammalian cardiac and glial cells. J Pharmacol Exp Ther. 1990;254:560-569.
43. Levine JW, Spear JF, Guarnieri T, Weisfeldt ML, Becker LC, Moore EN. Cesium chloride-induced long QT syndrome: demonstration of afterdepolarizations and triggering activity in vivo. Circulation. 1985;72:1092-1103.