메뉴 건너뛰기




Volumn 248, Issue 1, 1995, Pages 97-105

Selection and application of human single chain Fv antibody fragments from a semi-synthetic phage antibody display library with designed CDR3 regions

Author keywords

Competitive selection; Designed HCDR3 regions; Human antibodies; Phage display; Synthetic libraries

Indexed keywords


EID: 0028926814     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1995.0204     Document Type: Article
Times cited : (162)

References (27)
  • 1
    • 0027485049 scopus 로고
    • Construction of a human Ig combinatorial library from genomic V segments and synthetic CDR3 fragments
    • Akamatsu, Y., Cole, M. S., Yun Tso, J. & Tsurushita, N. (1993). Construction of a human Ig combinatorial library from genomic V segments and synthetic CDR3 fragments. J. Immunol. 151, 4651-4659.
    • (1993) J. Immunol. , vol.151 , pp. 4651-4659
    • Akamatsu, Y.1    Cole, M.S.2    Yun Tso, J.3    Tsurushita, N.4
  • 2
    • 0026563253 scopus 로고
    • Semisynthetic combinatorial antibody libraries: A chemical solution to the diversity problem
    • Barbas, C. F., III, Bain, J. D., Hoekstra, D. M. & Lerner, R. A. (1992). Semisynthetic combinatorial antibody libraries: a chemical solution to the diversity problem. Proc. Nat. Acad. Sci., U.S.A. 89, 4457-4461.
    • (1992) Proc. Nat. Acad. Sci., U.S.A. , vol.89 , pp. 4457-4461
    • Barbas, C.F.1    Bain, J.D.2    Hoekstra, D.M.3    Lerner, R.A.4
  • 4
    • 0025027382 scopus 로고
    • Prevalence of anti-group B streptococcal type III capsular IgG antibodies in the United Kingdom and an analysis of their specific IgG subclasses
    • Feldman, R. G. & Ferrante, A. (1994). Prevalence of anti-group B streptococcal type III capsular IgG antibodies in the United Kingdom and an analysis of their specific IgG subclasses. J. Infect. Dis. 162, 883-887.
    • (1994) J. Infect. Dis. , vol.162 , pp. 883-887
    • Feldman, R.G.1    Ferrante, A.2
  • 7
    • 0028197368 scopus 로고
    • HMG domain proteins: Architectural elements in the assembly of nucleoprotein structures
    • Grosschedl, R. R., Giese, K. & Pagel, J. (1994). HMG domain proteins: architectural elements in the assembly of nucleoprotein structures. Trends Genet. 10, 94-100.
    • (1994) Trends Genet , vol.10 , pp. 94-100
    • Grosschedl, R.R.1    Giese, K.2    Pagel, J.3
  • 9
    • 0002811466 scopus 로고
    • The hydrophilic surfactant protein sp-A: Molecular biology, structure and function
    • Robertson, B.V, 54, Elsevier Sci
    • Hawgood, S. (1992). The hydrophilic surfactant protein sp-A: molecular biology, structure and function. In Pulmonary Surfactant: From Molecular Biology to Clinical Practice (Robertson, B.V, ed.), pp. 33-54, Elsevier Science
    • (1992) Pulmonary Surfactant: From Molecular Biology to Clinical Practice , pp. 33-54
    • Hawgood, S.1
  • 10
    • 85027672822 scopus 로고
    • Epitope mapping of SCLC-cluster-2 mAbs and generation of antibodies directed against new EGP-2 epitopes
    • Helfrich, W., Wittop Koning P., The, H. T. & De Leij, L. (1994). Epitope mapping of SCLC-cluster-2 mAbs and generation of antibodies directed against new EGP-2 epitopes. Int. J. Cancer. Suppl. 8, 1.
    • (1994) Int. J. Cancer. Suppl. , vol.8 , pp. 1
    • Helfrich, W.1    Wittop Koning, P.2    The, H.T.3    De Leij, L.4
  • 11
    • 15744403561 scopus 로고
    • High level, stable production of recombinant proteins in mammalian cell culture using the herpesvirus VP16 transactivator
    • Hippenmeyer, P. & Highkin, M. (1993). High level, stable production of recombinant proteins in mammalian cell culture using the herpesvirus VP16 transactivator. Bio. Tech. 11, 1037-1041.
    • (1993) Bio. Tech. , vol.11 , pp. 1037-1041
    • Hippenmeyer, P.1    Highkin, M.2
  • 12
    • 0026673067 scopus 로고
    • By-passing immunisation. Human antibodies from synthetic repertoires of germline VH gene segments rearranged
    • H gene segments rearranged in vitro. J. Mol. Biol. 227, 381-388.
    • (1992) In Vitro. J. Mol. Biol , vol.227 , pp. 381-388
    • Hoogenboom, H.R.1    Winter, G.2
  • 14
    • 0025823716 scopus 로고
    • Identical V region amino acid sequences and segments of sequences in antibodies of different specificities
    • Kabat, E. A. & Wu, T. T. (1991). Identical V region amino acid sequences and segments of sequences in antibodies of different specificities. J. Immunol. 147, 1709-1719.
    • (1991) J. Immunol. , vol.147 , pp. 1709-1719
    • Kabat, E.A.1    Wu, T.T.2
  • 17
    • 0022618733 scopus 로고
    • Production of anti-thyro-globulin antibody by blood lymphocytes from patients with autoimmune thyroiditis, induced by the insolubilized antigen
    • Logtenberg, T., Kroon, A., Gmelig-Meyling, F. H. J. & Ballieux, R. E. (1986). Production of anti-thyro-globulin antibody by blood lymphocytes from patients with autoimmune thyroiditis, induced by the insolubilized antigen. J. Immunol. 136, 1236-1240.
    • (1986) J. Immunol. , vol.136 , pp. 1236-1240
    • Logtenberg, T.1    Kroon, A.2    Gmelig-Meyling, F.H.J.3    Ballieux, R.E.4
  • 19
    • 0025964038 scopus 로고
    • Structure, function and properties of antibody binding sites
    • Mian, I. S., Bradwell, A. R. & Olson, A. J. (1991). Structure, function and properties of antibody binding sites. J. Mol. Biol. 217, 133-151.
    • (1991) J. Mol. Biol. , vol.217 , pp. 133-151
    • Mian, I.S.1    Bradwell, A.R.2    Olson, A.J.3
  • 20
    • 0026066608 scopus 로고
    • PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1
    • Monica, K., Galili, N., Nourse, J., Satman, D. & Cleary M. L. (1991). PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1. Mol. Cell. Biol. 11, 6149-6157.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 6149-6157
    • Monica, K.1    Galili, N.2    Nourse, J.3    Satman, D.4    Cleary, M.L.5
  • 21
    • 0028006072 scopus 로고
    • Antibody fragments from a ‘single pot’ phage display library as immunochemical reagents
    • Nissim, A., Hoogenboom, H. R., Tomlinson, I. M., Flynn, G., Midgley C., Lane, D. & Winter, G. (1994). Antibody fragments from a ‘single pot’ phage display library as immunochemical reagents. EMBO J. 13, 692-698.
    • (1994) EMBO J , vol.13 , pp. 692-698
    • Nissim, A.1    Hoogenboom, H.R.2    Tomlinson, I.M.3    Flynn, G.4    Midgley, C.5    Lane, D.6    Winter, G.7
  • 22
    • 0028289241 scopus 로고
    • Anatomy of the antibody molecule
    • Padlan, E. A. (1994). Anatomy of the antibody molecule. Mol. Immunol. 31, 169-217.
    • (1994) Mol. Immunol. , vol.31 , pp. 169-217
    • Padlan, E.A.1
  • 23
    • 0023869530 scopus 로고
    • An inhibition enzyme immunoassay for estimating relative antibody affinity and affinity heterogeneity
    • Rath, S., Stanley C. M. & Steward, M. D. (1988). An inhibition enzyme immunoassay for estimating relative antibody affinity and affinity heterogeneity. J. Immunol. Methods, 106, 245-249.
    • (1988) J. Immunol. Methods , vol.106 , pp. 245-249
    • Rath, S.1    Stanley, C.M.2    Steward, M.D.3
  • 24
    • 0026323664 scopus 로고
    • Von Willebrand Factor
    • Sadler, J. E. (1991). von Willebrand Factor. J. Biol. Chem. 266, 22777-22780.
    • (1991) J. Biol. Chem. , vol.266 , pp. 22777-22780
    • Sadler, J.E.1
  • 25
    • 0026785856 scopus 로고
    • The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops
    • Tomlinson, I. M., Walter, G., Marks, J. D., Llewelyn, M. B. & Winter, G. (1992). The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops. J. Mol. Biol. 227, 776-798.
    • (1992) J. Mol. Biol. , vol.227 , pp. 776-798
    • Tomlinson, I.M.1    Walter, G.2    Marks, J.D.3    Llewelyn, M.B.4    Winter, G.5
  • 26
    • 0027202197 scopus 로고
    • The sequence-specific high mobility group 1 box of TCF-1 adopts a predominantly a-helical conformation in solution
    • van Houte, L., van Oers, A., van de Wetering, M., Dooijes, D., Kaptein, R. & Clevers, H. (1993). The sequence-specific high mobility group 1 box of TCF-1 adopts a predominantly a-helical conformation in solution. J. Biol. Chem. 268, 18083-18087.
    • (1993) J. Biol. Chem. , vol.268 , pp. 18083-18087
    • Van Houte, L.1    Van Oers, A.2    Van De Wetering, M.3    Dooijes, D.4    Kaptein, R.5    Clevers, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.