Defective lymphoid development in mice lacking expression of the common cytokine receptor γ chain

Immunity

Volumn 2, Issue 3, 1995, Pages 223-238

  Cao, Xiqing ^a   Shores, Elizabeth W ^d   Hu Li, Jane ^b   Anver, Miriam R ^e   Kelsail, Brian L ^b   Russell, Sarah M ^a   Drago, John ^c   Noguchi, Masayuki ^a   Grinberg, Alexander ^c   Bloom, Eda T ^d   Paul, William E ^e   Katz, Stephen I ^e   Love, Paul E ^c   Leonard, Warren J ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^d CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^e NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; CYTOKINE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; COMBINED IMMUNODEFICIENCY; CONTROLLED STUDY; DEVELOPMENT; GENETIC DISORDER; IMMUNE DEFICIENCY; LYMPHOID TISSUE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR GENE;

ANIMAL; B-LYMPHOCYTES; BASE SEQUENCE; CECAL DISEASES; CELL DIFFERENTIATION; DENDRITIC CELLS; EPITHELIAL CELLS; FEMALE; FLOW CYTOMETRY; INFLAMMATION; KILLER CELLS, NATURAL; LYMPHOCYTE SUBSETS; LYMPHOID TISSUE; MALE; MICE; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; RECEPTORS, INTERLEUKIN; SUPPORT, NON-U.S. GOV'T; T-LYMPHOCYTES;

EID: 0028925778     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/1074-7613(95)90047-0     Document Type: Article

References (62)

1. The immunobiology of T cells with invariant y8 antigen receptors
2. The interleukin (IL)-2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T cell proliferation and the induction of lymphokine activated killer cells
3. + thymocytes selected by MHC class I molecules
4. Dendritic epidermal T cells lesson from mice for humans
5. Quantification of natural cytotoxicity by human lymphocyte subpopulations isolated by density: heterogeneity of the effector cells
6. Cellular and molecular mechanisms of the IL-12-induced increase in allo-specific murine cytolytic T cell activity: implications for the age-related decline in CTL
7. c chain of the IL-2 receptor
8. A novel X-linked combined immunodeficiency disease
9. Characterization of cDNAs encoding the murine interleukin 2 receptor (IL-2R) γ chain: chromosomal mapping and tissue specificity of IL-2R γ chain expression
10. IL-4 induces IL-2 receptor p75 β-chain gene expression and IL-2-dependent proliferation in mouse T lymphocytes
11. + thymocytes
12. Molecular approaches to analysis of X-linked immunodeficiencies
13. Interleukin-2 receptor γ chain mutations in X-linked severe combined immunodeficiency disease result in the loss of highaffinity IL-2 receptor binding
14. Defective human interleukin 2 receptor y chain in an atypical X chromosome-linked severe combined immunodeficiency with peripheral T cells
15. Domestic animal models of severe combined immunodeficiency: canine X-linked severe combined immunodeficiency and severe combined immunodeficiency in horses
16. Utilization of the β and γ chains of the IL-2 receptor by the novel cytokine IL-15
17. Severe combined immunodeficiency disease: a pathological analysis of 26 cases
18. Inhibition of murine B and T cell lymphopoiesis in vivo by anti-IL-7 monoclonal antibody
19. + dendritic epidermal cells of adult mice from fetal thymic precursors
20. IL-2Rγ gene microdeletion demonstrates that canine X-linked severe combined immunodeficiency is a homologue of the human disease
21. Effects of the deregulated expression of human interleukin-2 in transgenic mice
22. Impairment of ligand binding and growth signaling of mutant IL-2 receptory-chains in patients with X-linked severe combined immunodeficiency
23. Origin of murine B cell lineages
24. Sharing of the interleukin-2 (IL-2) receptor y chain between receptors for IL-2 and IL-4
25. Functional participation of the IL-2 receptor y chain in IL-7 receptor complexes
26. Requirement of tyrosine phosphorylation for rapid activation of a DNA binding factor by IL-4
27. Generation and analysis of interleukin-4 deficient mice
28. Simplified mammalian DNA isolation procedure
29. − T cells in mice and humans
30. Basic aspects of intraepithelial lymphocyte immunobiology
31. The defective gene in X-linked severe combined immunodeficiency encodes a shared interleukin receptor subunit: implications for cytokine pleiotropy and redundancy
32. c
33. The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15
34. T cell development in mice that lack the ζ chain of the T cell antigen receptor complex
35. Differential effects of ζ and ν transgenes on early α/β T cell development.
36. Keratinocyte-derived IL-7 serves as a growth factor for dendritic epidermal T cells in mice
37. Functional activation of Jakl and Jak3 by selective association with IL-2 receptor subunits
38. Pathology of the thymus in immunodeficiency states
39. Characterization of the human interleukin-2 receptor γ gene
40. Interleukin-2 receptor γ chain: a functional component of the interleukin-7 receptor
41. Interleukin-2 receptor γ chain mutation results in X-linked severe combined immunodeficiency in humans
42. lck for thymic development of transgenic γδ T cells
43. Early lymphocyte expansion is severely impaired in interleukin 7 receptordeficient mice
44. X-linked immunodeficiencies
45. The interleukin-2 receptor γ chain maps to Xg13.1 and is mutated in X-linked severe combined immunodeficiency, SCIDX1
46. A retroviral vector for gene therapy of X-linked SCID
47. Use of antibiotics to prevent hepatitis and typhlitis in male SCID mice spontaneously infected with Helicobacter hepaticus
48. Interleukin-2 receptor γ chain: a functional component of the interleukin-4 receptor
49. Interaction of IL-2Rβ and γc chains with Jakl and Jak3: implications for XSCID and XCID
50. Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene
51. Development and proliferation of lymphocytes in mice deficient for both interleukins-2 and -4
52. Missense mutation in axon 7 of the common γ chain gene causes a moderate form of X-linked combined immunodeficiency
53. Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting
54. The IL-2 receptor β chain (p70): role in mediating signals for LAK, NK, and proliferative activities
55. Histologic characterization of the thymus in canine X-linked severe combined immunodeficiency
56. T lymphocyte depletion and function in dogs with X-finked severe combined immunodeficiency
57. Cloning of the γ chain of the human IL-2 receptor
58. + dendritic epidermal cells
59. Dendritic epidermal T cells: activation requirements and phenotypic characterization of proliferating cells
60. Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl protooncogene
61. Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors
62. Chronic active hepatitis and associated liver tumors in mice caused by a persistent bacterial infection with a novel Helicobacter species