Mechanism of inhibition of HIV-1 reverse transcriptase by nonnucleoside inhibitors

Science

Volumn 267, Issue 5200, 1995, Pages 988-993

  Spence, Rebecca A ^a   Kati, Warren M ^b   Anderson, Karen S ^c   Johnson, Kenneth A ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b ABBOTT LABORATORIES   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

9 CHLORO 4,5,6,7 TETRAHYDRO 5 METHYL 6 (3 METHYL 2 BUTENYL)IMIDAZO[4,5,1 JK][1,4]BENZODIAZEPINE 2(1H) THIONE; ANTIVIRUS AGENT; NEVIRAPINE; RNA DIRECTED DNA POLYMERASE; VIRUS ENZYME;

ARTICLE; CONFORMATIONAL TRANSITION; DRUG DNA BINDING; ENZYME INHIBITION; HUMAN IMMUNODEFICIENCY VIRUS 1; POLYMERIZATION; PRIORITY JOURNAL; VIRUS INHIBITION;

ANTIVIRAL AGENTS; BENZODIAZEPINES; BINDING SITES; DEOXYADENINE NUCLEOTIDES; DNA; HIV-1; HIV-1 REVERSE TRANSCRIPTASE; IMIDAZOLES; KINETICS; MAGNESIUM; NEVIRAPINE; PROTEIN CONFORMATION; PYRIDINES; REVERSE TRANSCRIPTASE INHIBITORS; RNA-DIRECTED DNA POLYMERASE; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0028925773     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.7532321     Document Type: Article

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