Flavonoid Intake and Long-term Risk of Coronary Heart Disease and Cancer in the Seven Countries Study

Archives of Internal Medicine

Volumn 155, Issue 4, 1995, Pages 381-386

  Hertog, Michaël G L ^a   Kromhout, Daan ^a   Aravanis, Christ ^b   Blackburn, Henry ^c   Buzina, Ratko ^d   Fidanza, Flaminio ^e   Giampaoli, Simona ^f   Jansen, Annemarie ^a   Menotti, Alessandro ^c,e   Nedeljkovic, Srecko ^g   Pekkarinen, Maija ^h   Simic, Bozidar S ⁱ   Toshima, Hironori ^j   Feskens, Edith J M ^a   Hollman, Peter C H ^k   Katan, Martijn B ^k  

^a NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^b Greek Atherosclerosis Society   (Greece)

^c UNIVERSITY OF MINNESOTA   (United States)

^d University Clinic for Endocrinology and Metabolic Diseases   (Croatia)

^e UNIVERSITY OF PERUGIA   (Italy)

^f ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^g UNIVERSITY OF BELGRADE   (Serbia)

^h UNIVERSITY OF HELSINKI   (Finland)

ⁱ Unit of Surgery   (Finland)

^j KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^k WAGENINGEN UNIVERSITY   (Netherlands)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; FLAVONOID; QUERCETIN;

ADULT; ALCOHOL CONSUMPTION; ANTIOXIDANT ACTIVITY; ARTICLE; CANCER RISK; CARCINOGENESIS; CIGARETTE SMOKING; CORONARY RISK; DIETARY INTAKE; DISEASE ASSOCIATION; FEMALE; FOLLOW UP; FOOD INTAKE; HUMAN; HUMAN EXPERIMENT; ISCHEMIC HEART DISEASE; MALE; MORTALITY; PRIORITY JOURNAL; STATISTICAL ANALYSIS;

ADULT; BIOFLAVONOIDS; CAUSE OF DEATH; COHORT STUDIES; COMPARATIVE STUDY; CORONARY DISEASE; CROSS-CULTURAL COMPARISON; DIET; EUROPE; HUMAN; JAPAN; MALE; MIDDLE AGE; NEOPLASMS; RISK FACTORS; SUPPORT, NON-U.S. GOV'T;

EID: 0028925089     PISSN: 00039926     EISSN: 15383679     Source Type: Journal    
DOI: 10.1001/archinte.1995.00430040053006     Document Type: Article

References (29)

1. Hertog MGL, Hollman PCH, Katan MB. Content of potentially anticarcinogenic flavonoids of 28 vegetables and 9 fruits commonly consumed in the Netherlands. J Agric Food Chem. 1992;40:2379-2383.
2. Hertog MGL, Hollman PCH, van de Putte B. Content of potentially anticarcinogenic flavonoids of tea infusions, wines, and fruit juices. J Agric Food Chem. 1993;41:1242-1246.
3. Hertog MGL, Hollman PCH, Katan MB, Kromhout D. Estimation of daily intake of potentially anticarcinogenic flavonoids and their determinants in adults in the Netherlands. Nutr Cancer. 1993;20:21-29.
4. Kühnau J. The flavonoids: a class of semi-essential food components: their role in human nutrition. World Rev Nutr Diet. 1976;24:117-120.
5. Deschner EE, Ruperto J, Wong G, Newmark HL. Quercetin and rutin as inhibitors of azoxymethanol-induced colonic neoplasia. Carcinogenesis. 1991;7: 1193-1196.
6. Mukhtar H, Das M, Khan WA, Wang ZY, Bik DP, Bickers DR. Exceptional activity of tannic acid among naturally occurring plant phenols in protecting against 7,12 dimethylbenz(a)anthracene-, benzo(a)pyrene-, 3-methylcholanthrene-, and N-methyl-N-nitrosourea-induced skin tumorigenesis in mice. Cancer Res. 1988; 48:2361-2365.
7. Verma AK, Johnson JA, Gould MN, Tanner MA. Inhibition of 7,12 dimethylbenz(a)anthracene and N-nitrosomethylurea induced rat mammary cancer by dietary flavonol quercetin. Cancer Res. 1988;48:5754-5788.
8. Ranelletti FO, Ricci R. Larocca LM, et al. Growth-inhibitory effect of quercetin and presence of type-II estrogen-binding sites in human colon cancer cell lines and primary colorectal tumors. Int J Cancer. 1992;50:486-492.
9. Robak J, Gryglewski RJ. Flavonoids are scavengers of superoxide anion. Biochem Pharmacol. 1988;37:83-88.
10. Husain SR, Cillard J, Cillard P. Hydroxy radical scavenging activity of flavonoids. Phytochemistry. 1987;26:2489-2492.
11. Takahama U. Inhibition of lipoxygenase-dependent lipid peroxidation by quercetin: mechanism of antioxidative function. Phytochemistry. 1985;24:1443-1446.
12. De Whalley CV, Rankin SM, Hoult JRS, Jessup W, Leake DS. Flavonoids inhibit the oxidative modification of low density lipoproteins. Biochem Pharmacol. 1990;39:1743-1749.
13. Negre-Salvagyre A, Salvagyre R. Quercetin prevents the cytotoxicity of oxidized low-density lipoproteins by macrophages. Free Radic Biol Med. 1992; 12:101-106.
14. Hertog MGL, Feskens EJM, Hollman PCH, Katan MB, Kromhout D. Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study. Lancet. 1993;342:1007-1011.
15. Hertog MGL, Feskens EJM, Hollman PCH, Katan MB, Kromhout D. Dietary antioxidant flavonoids and cancer risk in the Zutphen Elderly Study. Nutr Cancer. 1994;22:175-184.
16. Keys A, Aravanis C, Blackburn H. Epidemiological studies related to coronary heart disease: characteristics of men aged 40-59 in seven countries. Acta Med Scand. 1967;460(suppl):1-392.
17. Kromhout D, Keys A, Aravanis C, et al. Food consumption patterns in the 1960s in seven countries. Am J Clin Nutr. 1989;49:889-894.
18. Hertog MGL, Hollman PCH, Venema DP. Optimization of a quantitative HPLC determination of potentially anticarcinogenic flavonoids in vegetables and fruits. J Agric Food Chem. 1992;40:1591-1598.
19. SAS/STAT User's Guide: Release 6.03. 4th ed. Cary, NC: SAS Institute; 1990.
20. Keys A, Menotti A, Karvonen MJ, et al. The diet and 15-year death rate in the Seven Countries Study. Am J Epidemiol. 1986;124:903-915.
21. Wynder EL, Taioli E, Fujita Y. Ecologic study of lung cancer risk factors in the US and Japan, with special reference to smoking and diet. Jpn J Cancer Res. 1992;83:418-423.
22. Jinxiang X, Lesaffre E, Kesteloot H. The relation between animal fat intake, cigarette smoking, and lung cancer. Cancer Causes Control. 1991;2:79-83.
23. Willett W. The search for the causes of breast and colon cancer. Nature. 1989; 338:389-394.
24. Nomura A, Grove JS, Stemmermann GN, Severson RK. A prospective study of stomach cancer and its relation to diet, cigarettes, and alcohol consumption. Cancer Res. 1990;50:627-631.
25. Salonen JT, Ylä-Herttuala S, Yamamoto R, et al. Autoantibody against oxidized LDL and progression of carotid atherosclerosis. Lancet. 1992;339: 883-887.
26. The Eurogast Study Group. An international association between Helicobacter pylori infection and gastric cancer. Lancet. 1993;341:1359-1362.
27. Annual Bulletin of Tea Statistics. London, England: International Tea Committee; 1990.
28. Frankel EN, Kanner J, German JB, Parks E, Kinsella JE. Inhibition of oxidation of human low-density lipoprotein by phenolic substances in red wine. Lancet. 1993;341:454-457.
29. Conney AH, Wang Z-Y, Huang M-T, Ho C-T, Yang CS. Inhibitory effect of green tea on tumorigenesis by chemicals and ultraviolet light. Prev Med. 1992;21: 361-369.