Murine Liver Homogentisate 1,2‐Dioxygenase: Purification to Homogeneity and Novel Biochemical Properties

European Journal of Biochemistry

Volumn 228, Issue 2, 1995, Pages 425-430

  Schmidt, Stefan R ^a   Müller, Clemens R ^a   Kress, Wolfram ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Alkaptonuria; amino acid metabolism; aromatic ring cleavage; homogentisate 1,2 dioxygenase; metalloenzyme

Indexed keywords

HOMOGENTISATE 1,2 DIOXYGENASE; LIVER ENZYME; OXIDOREDUCTASE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME PURIFICATION; GEL FILTRATION; LIVER; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPECTROPHOTOMETRY;

ANIMAL; ASCORBIC ACID; HYDROGEN-ION CONCENTRATION; KINETICS; LIVER; MICE; OXYGENASES; SUPPORT, NON-U.S. GOV'T;

ANIMALIA; ARRHENIUS; MURINAE;

EID: 0028921205     PISSN: 00142956     EISSN: 14321033     Source Type: Journal    
DOI: 10.1111/j.1432-1033.1995.00425.x     Document Type: Article

References (14)

1. Purification and properties of homogentisate oxygenase from pseudomonas fluorescens
2. A rapid and sensitive method for the quantita‐tion of microgram quantities of protein utilizing the principle of protein‐dye binding
3. Homogentisic acid oxidase. II. Properties of the crude enzyme in rat liver
4. Purification of mammalian homogentisate oxidase and evidence for the existence of ferrous mercaptans in the active center
5. The Croonian lectures on inborn errors of metabolism. Lecture II. Alkaptonuria
6. Bacterial aromatic ring‐cleavage enzymes are classified into two different gene families
7. Gentisate 1,2‐dioxygenase from pseudomonas
8. Homogentisate oxidase of liver
9. The nature of the defect in tyrosine metabolism in alcaptonuria
10. aku, a mutation of the mouse homolougous to human alkaptonuria, maps to chromosome 16
11. Inhibition and activation of the oxidation of homogentisic acid
12. Metabolism of tyrosine. II. Homogentisicase
13. Bovine liver homogentisicase: Apo‐ and reconstituted holoenzymes
14. Studies on homogentisicase. I. Purification and the role of ferrous ion in the enzymic action