Pathogenesis of virus-induced diabetes in mice

Journal of Infectious Diseases

Volumn 171, Issue 5, 1995, Pages 1131-1138

  See, Darryl M ^a   Tilles, Jeremiah G ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; GAMMA INTERFERON; GLUCOSE; INSULIN; PANCREAS ISLET CELL ANTIBODY; VIRUS ANTIGEN; VIRUS PROTEIN; VIRUS RNA;

AGAR GEL ELECTROPHORESIS; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; COXSACKIE VIRUS B4; CYTOTOXICITY; DIABETES MELLITUS; FLUORESCENCE MICROSCOPY; MALE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RADIOIMMUNOASSAY;

ANIMAL; AUTOANTIBODIES; BASE SEQUENCE; BLOOD GLUCOSE; COXSACKIEVIRUS INFECTIONS; CYTOTOXICITY TESTS, IMMUNOLOGIC; DIABETES MELLITUS; ENTEROVIRUS B, HUMAN; INSULIN; ISLETS OF LANGERHANS; MALE; MICE; MOLECULAR SEQUENCE DATA; ORGAN SPECIFICITY; PANCREAS; RNA, VIRAL;

EID: 0028919543     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/171.5.1131     Document Type: Article

References (30)

1. Wagenknect LE, Roseman JM, Herman WH. Increased incidence of insulin-dependent diabetes mellitus following an epidemic of coxsackievirus B5. Am J Epidemiol 1991; 133:1024-31
2. Szopa M, Ward T, Dronfield DM, Portwood ND, Taylor KW. Coxsackie B4 viruses with the potential to damage beta cells of the islets are present in clinical isolates. Diabetologia 1990;33:325-8
3. Frisk G, Friman G, Tuvemao T, Fohlman J, Diederholm H. Coxsackie B virus IgM in children at onset of type 1 (insulin-dependent) diabetes mellitus: evidence for IgM induction by a recent or current infection. Diabetologia 1992;35:249-53
4. D’Alessio DJ. A case-control study of group B coxsackievirus immunoglobulin M antibody prevalence and HLA-DR antigens in newly diagnosed cases of insulin-dependent diabetes mellitus. Am J Epidemiol 1992;135:1331-8
5. Craighead JE. The role of viruses in the pathogenesis of pancreatic disease and diabetes mellitus. Prog Med Virol 1975; 19:161-214
6. Notkins AL, Onodera T, Prabhakar BS. Virus induced autoimmunity. In: Notkins AL, Oldstone MBA. eds. Concepts in viral pathogenesis. New York: Springer-Verlag, 1984:210-5
7. Gerling I. Baekkeskov S. Lernmark A, Islet cell and 64K autoantibodies are associated with plasma IgG in newly diagnosed insulin-dependent diabetic children. J Immunol 1986;137:3782-5
8. Baekkeskov S, Dyrbert T, Lernmark A. Autoantibodies to a 64-kilodal- ton islet cell protein precede the onset of spontaneous diabetes in the BB rat. Science 1984;224:1348-50
9. Gerling I, Chatterjee NK, Nejman C. Coxsackievirus B4-induced development of antibodies to 64, 000-Mr islet autoantigen and hyperglycemia in mice. Autoimmunity 1991;10:49-56
10. Richter W. Endl J, Eiermann TH, et al. Human monoclonal islet cell antibodies from a patient with insulin-dependent diabetes mellitus reveal glutamate decarboxylase as the target antigen. Proc Natl Acad Sei USA 1992;89:8467-71
11. Atkinson MA, Bowman MA, Campbell L, Darrow BL. Kaufman DL, Maclaren NK. Cellular immunity to a determinant common to glutamate decarboxylase and coxsackie virus in insulin-dependent diabetes. J Clin Invest 1994;94:2125-9
12. Gerling I, Nejman C, Chatterjee NK. Effect of coxsackievirus B4 infection in mice on expression of 64, 000-Air autoantigen and glucose sensitivity of islets before development of hyperglycemia. Diabetes 1988;37:1219-25
13. Baek HS, Yoon JW. Role of macrophages in the pathogenesis of encephalomyocarditis virus-induced diabetes in mice. J Virol 1990;64:5708-15
14. Baek HS, Yoon JW. Direct involvement of macrophages in destruction of beta-cells leading to development of diabetes in virus-infected mice. Diabetes 1991;41:1586-97
15. Cavallo MG. Baroni MG. Toto A, et al. Viral infection induces cytokine release by beta islet cells. Immunology 1992;75:664-8
16. Hartig PC, Madge GE, Webb SR. Diversity within a human isolate of coxsackie B4: relationship to viral-induced diabetes. J Med Virol 1983;11:23-30
17. Webb SR, Loria RM, Madge GE, Kibrick S. Susceptibility of mice to group B coxsackievirus is influenced by the diabetic gene. J Exp Med 1976;143:1239-46
18. Yoon JW, Austin M, Onodera T, Notkins AL. Virus-induced diabetes mellitus: isolation of a virus from the pancreas of a child with diabetic ketoacidosis. N F.ngl J Med 1979;300:1173-9
19. See DM, lilies JG. Treatment of coxsackievirus A9 myocarditis in mice with WIN 54954. Antimicrob Agents Chemother 1992;36:425-8
20. See DM, Tilles JG. Efficacy ofa polyvalent inactivated-virus vaccine in protecting mice from infection with clinical strains of group B coxsackieviruses. Scand J Infect Dis 1994;26:739-47
21. Johnson GD. Immunofluorescence and immunoperoxidase techniques. In: Thompson, RA, ed. Techniques in clinical immunology. Boston: Blackwell Scientific Publications, 1981:122-3
22. Hales CN, Randle PJ. Immunoassay of insulin with insulin-antibody precipitate. J Biochem 1963;88:137-46
23. Smith LJ, Braylan RC, Nutkis JF., Edmundson KB, Downing JR, Wakeland EK. Extraction of cellular DNA from human cells and tissues fixed in ethanol. Anal Biochem 1987;160:135-8
24. See DM, Tilles JG. WIN 54954 treatment of mice infected with a diabetogenic strain of group B coxsackievirus. Antimicrob Agents Chemother 1993;165:207-16
25. Yoon JW, Notkins AL. Virus-induced diabetes mellitus. VI. Genetically determined host difference in the replication of encephalomyo-carditis virus in pancreatic B-cells. J Exp Med 1976; 143:1170-85
26. Appels B, Burkart V, Kantwerk-Funke G, Funda J, Kolb-Bachofen V, Kolb H. Spontaneous cytotoxicity of macrophages against pancreatic islet cells. J Immunol 1989;142:3803-8
27. Pukel C. Baquerizo H. Rabinovich A. Destruction of rat islet cell mono layers by cytokines. Synergistic interactions of interferon-gamma, tumor necrosis factor, lymphotoxin, and interleukin-l. Diabetes 1988;37:133-6
28. Kroncke KD, Kolb-Bachofen V, Berschick B, Burkart V. Kolb H. Activated macrophages kill pancreatic syngeneic islet cells via arginine-dependent nitric oxide generation. Biochem Biophys Res Commun 1991;175:752-8
29. Kanatsuna T. Baekkeskov S, Lernmark A, Ludvigsson J. Immunoglobulin from insulin-dependent diabetic children inhibits glucose induced insulin release. Diabetes 1983;32:520-4
30. Sai P, Boitard C., Debray-Sachs M, Pouplard A, Assan R, Hamburger J. Complement-fixing islet cell antibodies from some diabetic patients alter insulin release in vitro. Diabetes 1981;30:1951-4