Stabilization of double-stranded oligonucleotides using backbone-linked disulfide bridges

Nucleic Acids Research

Volumn 23, Issue 2, 1995, Pages 285-292

  Gao, Hetian ^a   Yang, Meihua ^a   Cook, Alan F ^a  

^a PharmaGenics Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISULFIDE; DOUBLE STRANDED DNA; OLIGONUCLEOTIDE; THIOL DERIVATIVE;

ARTICLE; DISULFIDE BOND; DNA STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; STRUCTURE ANALYSIS; THERMOSTABILITY;

BASE SEQUENCE; BLOOD; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYRIBONUCLEASE ECORI; DISULFIDES; DITHIOTHREITOL; DRUG STABILITY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HEAT; HUMAN; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; OLIGONUCLEOTIDES; OXIDATION-REDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0028917942     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/23.2.285     Document Type: Article

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