Prevention of in vitro neutrophil-endothelial attachment through shedding of L-selectin by nonsteroidal antiinflammatory drugs

Journal of Clinical Investigation

Volumn 95, Issue 4, 1995, Pages 1756-1765

  Díaz González, Federico ^a   González Alvaro, Isidoro ^a   Campanero, Miguel R ^a   Mollinedo, Faustino ^b   Del Pozo, Miguel A ^a   Muñoz, Cecilia ^a   Pivel, Juan P ^a   Sánchez Madrid, Francisco ^a,c  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^c HOSPITAL UNIVERSITARIO DE LA PRINCESA   (Spain)

Author keywords

adhesion molecules; L selectin; neutrophils; nonsteroidal antiinflammatory drugs

Indexed keywords

ACETYLSALICYLIC ACID; CD11B ANTIGEN; CD31 ANTIGEN; CELL ADHESION MOLECULE; DICLOFENAC; GELATINASE; INDOMETACIN; INTERCELLULAR ADHESION MOLECULE 3; KETOPROFEN; L SELECTIN; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; LYSOZYME; MONOCLONAL ANTIBODY; N ACETYL BETA GLUCOSAMINIDASE; NONSTEROID ANTIINFLAMMATORY AGENT; PHORBOL 13 ACETATE 12 MYRISTATE; TUMOR NECROSIS FACTOR ALPHA;

ANTIGEN EXPRESSION; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL INTERACTION; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG MECHANISM; ENDOTHELIUM CELL; ENZYME RELEASE; HUMAN; HUMAN CELL; IMMUNOREGULATION; LEUKOCYTE ACTIVATION; LEUKOCYTE FUNCTION; NEUTROPHIL; PRIORITY JOURNAL;

EID: 0028916230     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI117853     Document Type: Article

References (48)

1. Butcher, E. C. 1991. Leukocyte endothelial cell migration: three (or more) steps to specificity and diversity. Cell. 67:1033-1036.
2. Shimizu, Y., W. Newman, Y. Tanaka, and S. Shaw. 1992. Lymphocyte interactions with endothelial cells. Immunol. Today. 13:106-112.
3. Springer, T. A. 1994. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell. 76:301-314.
4. Ley, K., P. Gaehtgens, C. Fennie, M. S. Singer, L. A. Lasky, and S. D. Rosen. 1991. Lectin-like cell adhesion molecule 1 mediate leukocyte rolling in mesenteric venules in vivo. Blood. 77:2553-2555.
5. von Andrian, U. H., J. D. Chambers, L. M. McEvoy, R. F. Bargatze, K. E. Arfors, and E. C. Butcher. 1991. Two-step model of leukocyte-endothelial cell interaction in inflammation: distinct roles of LECAM-1 and the leukocyte β2 integrins in vivo. Proc. Natl. Acad. Sci. USA. 88:7538-7542.
6. Lawrence, M. B., and T. A. Springer. 1991. Leukocytes roll on a selectin at physiologic flow rates: distinction from and prerequisite for adhesion through integrins. Cell. 65:859-873.
7. Zimmerman, G. A., S. M. Prescott, and T. M. McIntyre. 1992. Endothelial cell interactions with granulocytes: tethering and signaling molecules. Immunol. Today. 13:93-100.
8. McEver, R. P. 1992. Leukocyte-endothelial cell interactions. Curr. Opin. Cell Biol. 4:840-849.
9. Lasky, L. A. 1992. Selectins: interpreters of cell-specific carbohydrate information during inflammation. Science (Wash. DC). 258:964-969.
10. Stenberg, P. E., R. P. McEver, M. A. Shuman, Y. V. Jacques, and D. F. Bainton. 1985. A platelet alpha-granule membrane protein (GMP-140) is expressed on the plasma membrane after activation. J. Cell Biol. 101:880-886.
11. McEver, R. P., J. H. Beckstead, K. L. Moore, L. Marshall-Carlson, and D. F. Bainton. 1989. GMP-140, a platelet α-granule membrane protein, is also synthesized by vascular endothelial cells and is localized in Weibel-Palade bodies. J. Clin. Invest. 84:92-99.
12. Hsu-Lin, S. C., C. L. Berman, B. C. Furie, D. August, and B. Furie. 1984. A platelet membrane protein expressed during platelet activation and secretion. Studies using a monoclonal antibody specific for thrombin-activated platelets. J. Biol. Chem. 259:9121-9126.
13. Bevilacqua, M. P. 1993. Endothelial-leukocyte adhesion molecules. Annu. Rev. Immunol. 11:767-804.
14. Griffin, J. D., O. Spertini, T. J. Ernst, M. P. Belvin, H. B. Levine, Y. Kanakura, and T. F. Tedder. 1990. GM-CSF and other cytokines regulate surface expression of the leukocyte adhesion molecule-1 on human neutrophils, monocytes and their precursors. J. Immunol. 145:576-584.
15. Tedder, T. F., T. Matsuyama, D. M. Rothstein, S. F. Schlossman, and C. Morimoto. 1990. Human antigen-specific memory T cells express the homing receptor necessary for lymphocyte recirculation. Eur. J. Immunol. 20:1351-1355.
16. Lasky, L. A., M. S. Singer, D. Dowbenko, Y. Imai, W. J. Henzel, C. Grinley, C. Fennie, N. Gillet, S. R. Watson, and S. D. Rosen. 1992. An endothelial ligand for L-selectin is a novel mucin-like molecule. Cell. 69:927-938.
17. Baumhueter, S., M. S. Singer, W. J. Henzel, S. Hemmerich, M. Renz, S. D. Rosen, and L. A. Lasky. 1993. Binding of L-selectin to the vascular sialomucin CD34. Science (Wash. DC). 262:436-438.
18. Berg, E. L., L. M. McEvoy, C. Berlin, R. F. Bargatze, and E. C. Butcher. 1993. L-selectin-mediate lymphocyte rolling on MadCAM-1. Nature (Lond.). 366:695-698.
19. Picker, L. J., R. A. Warnock, A. R. Burns, C. M. Doerschuck, E. L. Berg, and E. C. Butcher. 1991. The neutrophil selectin LECAM-1 presents carbohydrate ligands to the vascular selectins ELAM-1 and GMP-140. Cell. 66:921-933.
20. Kishimoto, T. K., M. A. Jutila, E. L. Berg, and E. C. Butcher. 1989. Neutrophil Mac-1 and MEL-14 adhesion proteins inversely regulated by chemotactic factors. Science (Wash. DC). 245:1238-1241.
21. Berg, M., and S. P. James. 1990. Human neutrophils release the Leu-8 lymph node homing receptor during cell activation. Blood. 76:2381-2388.
22. Campanero, M. R., R. Pulido, J. L. Alonso, J. P. Pivel, F. X. Pimentel-Muiños, M. Fresno, and F. Sánchez-Madrid. 1991. Down-regulation by tumor necrosis factor alpha of neutrophil cell surface expression of the sialophorin CD43 and the hyaluronate receptor CD44 through a proteolytic mechanism. Eur. J. Immunol. 21:3045-3048.
23. Jutila, M. A., L. Rott, E. L. Berg, and E. C. Butcher. 1989. Function and regulation of the neutrophil MEL-14 antigen in vivo: comparison with LFA-1 and MAC-1. J. Immunol. 143:3318-3324.
24. Humbria, A., F. Díaz-González, M. R. Campanero, A. G. Arroyo, A. Laffón, R. González-Amaro, and F. Sánchez-Madrid. 1994. Expression of L-selectin, CD43 and CD44 in synovial fluid neutrophils from inflammatory joint disease. Evidence for a soluble form of L-selectin in synovial fluid. Arthritis Rheum. 37:342-348.
25. Schleiffenbaum, B., O. Spertini, and T. F. Tedder. 1992. Soluble L-selectin is present in human plasma at high levels and retains functional activity. J. Cell Biol. 119:229-238.
26. Langman, M. J. S. 1988. Ulcer complications and nonsteroidal anti-inflammatory drugs. Am. J. Med. 84(Suppl. 2):15-19.
27. Vane, J. R. 1971. Inhibition of prostaglandin synthesis as a mechanism of action for the aspirin-like drugs. Nature (Lond.). 231:232-235.
28. Abramson, S. B., and G. Weissman. 1989. The mechanism of action of nonsteroidal antiinflammatory drugs. Arthritis Rheum. 32:1-9.
29. Forrest, M., and P. M. Brooks. 1988. Mechanism of action of non-steroidal anti-rheumatic drugs. Clin. Rheumatol. 2:275-294.
30. Lacal, P., R. Pulido, F. Sánchez-Madrid, and F. Mollinedo. 1988. Intracellular location of T200 and Mol glycoproteins in human neutrophils. J. Biol. Chem. 263:9946-9951.
31. Campanero, M. R., M. A. del Pozo, A. G. Arroyo, P. Sánchez-Mateos, T. Hernández-Caselles, A. Craig, R. Pulido, and F. Sánchez-Madrid. 1993. ICAM-3 interacts with LFA-1 and regulates the LFA-1/ICAM-1 cell adhesion pathway. J. Cell. Biol. 123:1007-1016.
32. Spertini, O., G. S. Kansas, K. A. Reimann, C. R. Mackay, and T. Tedder. 1991. Function and evolutionary conservation of distinct epitopes on the leukocyte adhesion molecule-1 (TQ-1, Leu-8) that regulate leukocyte migration. J. Immunol. 147:942-949.
33. Sánchez-Madrid, F., J. Nagy, E. Robbins, P. Simon, and T. A. Springer. 1983. A human leukocyte differentiation antigen family with distinct α-subunits and a common β subunit: the lymphocyte function-associated antigen (LFA-1), the C3bi complement receptor (OKM1, Mac-1), and the p150,95 molecule. J. Exp. Med. 158:1785-1803.
34. Spertini, O., F. W. Luscinskas, J. M. Munro, G. S. Kansas, J. D. Griffin, M. A. Gimbrone, and T. F. Tedder. 1991. Leukocyte adhesion molecule (LAM-1, L-selectin) interacts with an inducible endothelial cell ligand to support leukocyte adhesion and transmigration. J. Immunol. 147:2565-2573.
35. Mollinedo, F., F. S. Manara, and D. L. Schneider. 1986. Acidification activity of human neutrophils. Tertiary granules as a site of ATP-dependent acidification. J. Biol. Chem. 261:1077-1082.
36. Spertini, O., F. W. Luscinskas, M. A. Gimbrone, Jr., and T. F. Tedder. 1992. Monocyte attachment to activated human vascular endothelium in vitro is mediated by leukocyte adhesion molecule-1 (L-selectin) under non-static conditions. J. Exp. Med. 175:1789-1792.
37. Miller, L. J., D. F. Bainton, N. Borregaard, and T. A. Springer. 1987. Stimulated mobilization of monocyte Mac-1 and p150,95 adhesion proteins from an intracellular vesicular compartment to the cell surface. J. Clin. Invest. 80:535-544.
38. Palencada, A., B. Walcheck, D. K. Bishop, and M. A. Jutila. 1992. Rapid activation-independent shedding of leukocyte L-selectin induced by cross-linking of the surface antigen. Eur. J. Immunol. 22:1279-1286.
39. Imai, Y., M. S. Singer, C. Fennie, L. A. Lasky, and S. D. Rosen. 1991. Identification of a carbohydrate-based endothelial ligand for a lymphocyte homing receptor. J. Cell. Biol. 113:1213-1221.
40. True, D. D., M. S. Singer, L. A. Lasky, and S. D. Rosen. 1990. Requirement for sialic acid on the endothelial ligand of a lymphocyte homing receptor. J. Cell. Biol. 111:2757-2764.
41. Yednock, T. A., L. M. Stoolman, and S. D. Rosen. 1987. Phosphomannosyl-derivatized beads detected a receptor involved in lymphocyte homing. J. Cell. Biol. 104:713-723.
42. Spertini, O., G. S. Kansas, J. M. Munro, J. D. Griffin, and T. F. Tedder. 1991. Regulation of leukocyte migration by activation of the leukocyte adhesion molecule-1 (LAM-1) selectin. Nature (Lond.). 349:691-694.
43. Watson, S. R., C. Fennie, and L. A. Lasky. 1991. Neutrophil influx into an inflammatory site inhibited by a soluble homing receptor-IgG chimaera. Nature (Lond.). 349:164-167.
44. Mulligan, M. S., J. C. Paulson, S. De Frees, Z. L. Zheng, J. B. Lowe, and P. A. Ward. 1993. Protective effects of oligosaccharides in P-selectin-dependent lung injury. Nature (Lond.). 364:149-151.
45. Travis, J. 1993. Biotech gets a grip on cell adhesion. Science (Wash. DC). 260:906-908.
46. Brooks, P. M., and R. O. Day. 1991. Nonsteroidal antiinflammatory drugs. Differences and similarities. N. Engl. J. Med. 324:1716-1725.
47. Kopp, E., and S. Ghosh. 1994. Inhibition of NF-KB by sodium salicylate and aspirin. Science (Wash. DC). 265:956-958.
48. Flower, R. J., S. Moncada, and J. R. Vane. 1980. Antipyretic, analgesic, and antiinflammatory agents. Drugs employed in the treatment of gout. In The Pharmacological Basis of Therapeutics. A. G. Goodman and L. H. Gilman, editors. MacMillan Publishing Co., New York. 682-698.