Halofuginone, A Specific Collagen Type I Inhibitor, Reduces Anastomotic Intimal Hyperplasia

Archives of Surgery

Volumn 130, Issue 3, 1995, Pages 257-261

  Choi, Eric T ^a   Callow, Allan D ^b   Sehgal, Niraj L ^c   Brown, David M ^a   Ryan, Una S ^b  

^a Department of Surgery ^*  (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HALOFUGINONE;

ARTERY INTIMA PROLIFERATION; ARTERY OCCLUSION; ARTICLE; BLOOD VESSEL SHUNT; CELL PROLIFERATION; CELL VIABILITY; DRUG INHIBITION; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER;

ANASTOMOSIS, SURGICAL; ANIMAL; BLOTTING, NORTHERN; CAROTID ARTERY, COMMON; CELL DIVISION; CELLS, CULTURED; COLLAGEN; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPERPLASIA; MUSCLE, SMOOTH, VASCULAR; PROCOLLAGEN; QUINAZOLINES; RABBITS; RNA, MESSENGER; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TROPOELASTIN; TUNICA INTIMA;

EID: 0028912774     PISSN: 00040010     EISSN: 15383644     Source Type: Journal    
DOI: 10.1001/archsurg.1995.01430030027004     Document Type: Article

References (27)

1. McBride W, Lange RA, Hillis LD. Restenosis after successful angioplasty: pathophysiology and prevention. N Engl J Med. 1988;318:1734-1737.
2. Liu MW, Roubin GS, King SB Jr. Restenosis after coronary angioplasty: potential biologic determinants and role of intimal hyperplasia. Circulation. 1989; 79:1374-1387.
3. Callow AD. Current status of vascular grafts. Surg Clin North Am. 1982;62: 501-513.
4. Stonebridge PA, Miller A, Tsoukas A, et al. Angioscopy of arm vein infrainguina bypass grafts. Ann Vasc Surg. 1991;5:170-175.
5. Sottiurai VS, Yao JS, Batson RC, Sue SL, Jones R, Nakamura YS. Distal anastomotic intimal hyperplasia: histopathologic character and biogenesis. Ann Vasc Surg. 1989;3:26-33.
6. Ferns GA, Stewart-Lee AL, Auggard EE. Arterial response to mechanical injury: balloon catheter de-endothelialization. Atherosclerosis. 1992;92:89-104.
7. Majesky MW, Reidy MA, Bowen-Pope DF, Hart CE, Wilcox JN, Schwartz SM. PDGF ligand and receptor gene expression during repair of arterial injury. J Cell Biol. 1990;111:2149-2158.
8. Lindner V, Lappi DA, Baird A, Majack RA, Reidy MA. Role of basic fibroblast growth factor in vascular lesion formation. Circ Res. 1991;68:106-113.
9. Manderson JA, Mosse PRL, Safstrom JA, Young SB, Campbell GR. Balloon catheter injury to rabbit carotid artery. Arteriosclerosis. 1989;9:289-298.
10. Desmouliere A, Lamaziere JMD, Larrue J. Phenotypic expression of surface antigens of rabbit aortic smooth muscle cells in culture. Atherosclerosis. 1990; 85:25-35.
11. Yamamoto M, Yamamoto K, Noumura T. Type I collagen promotes modulation of cultured rabbit arterial smooth muscle cells from a contractile to a synthetic phenotype. Exp Cell Res. 1993;204:121-129.
12. Sakata N, Kawamura K, Takebayashi S. Effects of collagen matrix on proliferation and differentiation of vascular smooth muscle cells in vitro. Exp Mol Pathol. 1990;52:179-191.
13. Hedin U, Bottger BA, Forsberg E, Johansson S, Thyberg J. Diverse effects of fibronectin and laminin on phenotypic properties of cultured arterial smooth muscle cells. J Cell Biol. 1988;107:307-319.
14. Choi ET, Engel L, Callow AD, et al. Inhibition of neointimal hyperplasia by blocking αvβ3 integrin with a small peptide antagonist Gpen GRGDSPCA. J Vasc Surg. 1994;19:125-134.
15. Zeymer U, Fishbein MC, Forrester JS, Cercek B. Proliferating cell nuclear antigen immunohistochemistry in rat aorta after balloon denudation: comparison with thymidine and bromodeoxyuridine labeling. Am J Pathol. 1992;141:685-690.
16. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem. 1987;162: 156-159.
17. Parks WC, Secrist H, Wu LC, Mecham RP. Development regulation of tropoelastin isoforms. J Biol Chem. 1988;263:4416-4423.
18. Chu ML, Myers JC, Bernard MP, Ding JF, Ramirez F. Cloning and characterization of five overlapping cDNAs specific for the human proα1(I) collagen chain. Nucleic Acids Res. 1982;10:5925-5934.
19. Liau G, Yamada Y, de Crombrugghe B. Coordinate regulation of the levels of type III and type I collagen mRNA in most but not all mouse fibroblasts. J Biol Chem. 1985;260:531-536.
20. Pierce RA, Deak SB, Stolle CA, Boyd CD. Heterogeneity of rat tropoelastin mRNA revealed by cDNA cloning. Biochemistry. 1990;29:9677-9683.
21. Granot I, Halevy O, Hurwitz S, Pines M. Halofuginone: an inhibitor of collagen type I synthesis. Biochem Biophys Acta. 1993;1156:107-112.
22. Granot I, Bartov I, Plavnik I, Wax E, Hurwitz S, Pines M. Increased skin tearing in broiler and reduced collagen synthesis in skin in vivo and in vitro in response to the coccidiostat halofuginone. Poult Sci. 1991;70:1559-1563.
23. Angel S, Weinberg ZG, Polishuk O, Heit M, Plavnik I, Bartov I. A connection between a dietary coccidiostat and skin tears of female broiler chickens. Poult Sci. 1985;64:294-296.
24. Graham MF, Drucker DEM, Perr HA, Diehelmann RF, Ehrlich HP. Heparin modulates human intestinal smooth muscle cell proliferation, protein synthesis, and lattice contraction. Gastroenterology. 1987;93:801-809.
25. Dietrich JW, Duffield R. Effects of the calcium antagonist verapamil on in vitro synthesis of skeletal collagen and noncollagen protein. Endocrinology. 1979; 105:1168-1172.
26. Hedin U, Thyberg J. Plasma fibronectin promotes modulation of arterial smooth muscle cells from contractile to synthetic phenotype. Differentiation. 1987;33: 239-246.
27. Lindner V, Reidy MA. Proliferation of smooth muscle cells after vascular injury is inhibited by an antibody against basic fibroblast growth factor. Proc Natl Acad Sci U S A. 1991;88:3739-3743.