Eating disorder and epilepsy in mice lacking 5-HT2C serotonin receptors

Nature

Volumn 374, Issue 6522, 1995, Pages 542-546

  Tecott, Laurence H ^a   Sun, Linda M ^a   Akana, Susan F ^a   Strack, Alison M ^a   Lowenstein, Daniel H ^a   Dallman, Mary F ^a   Julius, David ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; NEUROTRANSMITTER; SEROTONIN; SEROTONIN 2 RECEPTOR; SEROTONIN AGONIST;

ANIMAL CELL; APPETITE; ARTICLE; BRAIN; CENTRAL NERVOUS SYSTEM; DEATH; EPILEPSY; FEEDING BEHAVIOR; FEEDING DISORDER; FEMALE; MALE; MOUSE; MUTANT; NONHUMAN; OBESITY; PRIORITY JOURNAL; SPINAL CORD; TONIC SEIZURE;

NON-PROGRAMMATIC;

AMINO ACID SEQUENCE; ANIMAL; BASE SEQUENCE; BODY CONSTITUTION; BODY WEIGHT; BRAIN; EATING DISORDERS; EPILEPSY; MALE; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; MUTAGENESIS; OLIGODEOXYRIBONUCLEOTIDES; RATS; RECEPTORS, SEROTONIN; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; XENOPUS;

EID: 0028909857     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/374542a0     Document Type: Article

References (60)

1. Lasky, L. A. Science 258, 964-969 (1992).
2. Springer, T. A. Cell 76, 301-314 (1994).
3. Lawrence, M. B. and Springer, T, A. Cell 65, 859-873 (1991).
4. Dembo, M., Torney, D. C., Saxman, K. and Hammer, D. Proc. R. Soc. B234, 55-83 (1988).
5. Hammer, D. A. and Apte, S. M. Biophys. J. 63, 35-57 (1992).
6. Tozeren, A. and Ley, K. Biophys. J. 63, 700-709 (1992).
7. Beil, G. I. Science 200, 618-627 (1978).
8. Goldman, A. J., Cox, R. G. and Brenner, H. Chem. Engng Sci. 22, 653-660 (1967).
9. Tempelman, L. A. and Hammer, D. A. Biophys. J. 66, 1231-1243 (1994).
10. Sako, D. Cell 75, 1179-1186 (1993).
11. Moore, K. L. J. Cell Biol. 118, 445-456 (1992).
12. Moore, K. L. J. biol. Chem. 269, 23318-23327 (1994).
13. Ushiyama, S., Laue, T. M., Moore, K. L., Erickson, H. P. and McEver, R. P. J. biol. Chem. 268, 15229-15237 (1993).
14. Press, W. H., Flannery, B. P., Teukolsky, S. A. and Vetterling, W. T. Numerical Recipes: the Art of Scientific Computing (Cambridge Univ. Press, Cambridge, 1986).
15. Munson, P. J. and Rodbard, D. Analyt. Biochem. 107, 220-239 (1980).
16. Dowdy, S. and Wearden, S. Statistics for Research (Wiley, New York, 1985).
17. Erbe, D. V. J. Cell Biol. 119, 215-227 (1992).
18. Graves, B. J. Nature 367, 532-538 (1994).
19. Fersht, A, Enzyme Structure and Mechanism (Freeman, New York, 1985).
20. Erickson, H. P. Proc. natn. Acad. Sci. U.S.A. 91, 10114-10118 (1994).
21. Janin, J. and Chothia, C. J. biol. Chem. 265, 16027-16030 (1990).
22. Evans, E., Berk, D. and Leung, A. Biophys. J. 59, 838-848 (1991).
23. Bell, G. I., Dembo, M. and Bongrand, P. Biophys. J. 45, 1051-1064 (1984).
24. Kansas, G. S., Ley, K., Munro, J. M. and Tedder, T. F. J. exp. Med. 177, 833-838 (1993).
25. Mason, D. W. and Williams, A. F. in Handbook of Experimental Immunology Immuno- chemistry 4th edn (eds Weir, D. M., Herzenberg, L. A. and Blackwell, C.) Vol. 4, 381-38. (Blackwell, Oxford, 1986).
26. Kaplanski, G. Biophys. J. 64, 1922-1933 (1993).
27. Chan, P.-Y. J. Cell Biol. 115, 245-255 (1991).
28. Lawrence, M. B., Bainton, D. F. and Springer, T. A. Immunity 1, 137-145 (1994).
29. Geng, J.G. Nature 343, 757-760 (1990).
30. Steininger, C. N., Eddy, C. A., Leimgruber, R. M., Mellors, A. and Welply, J. K. Biochem. biophys. Res. Commun. 188, 760-766 (1992).
31. Jacobs, B. L. in Hallucinogens: Neurochemical, Behavioral, and Clinical Perspectives (ed. Jacobs, B. L.) 183-202 (Raven, New York, 1984).
32. Sleight, A. J., Pierce, P. A., Schmidt, A. W., Hekmatpanah, C. R. and Peroutka, S. J. in Serotonin Receptor Subtypes: Basic and Clinical Aspects (ed. Peroutka, S. J.) 211-227 (Wiiey-Liss, New York, 1991).
33. Wilkinson, L. O. and Dourish, C. T. in Serotonin Receptor Subtypes: Basic and Clinical Aspects (ed. Peroutka, S. J.) 147-210 (Wiiey-Liss, New York, 1991).
34. Tecott, L. H. and Julius, D. J. Curr. Opin. Neurobiol. 3, 310-315 (1993).
35. Julius, D., MacDermott, A. B., Axef, R. and Jessell, T. M. Science, 241, 558-564 (1988).
36. Molineaux, S., Jesseti, T., Axel, R. and Julius, D. Proc. natn. Acad. Sci. U.S.A. 86, 6793-6797 (1989).
37. Hoffman, B. J. and Mezey, E. FEBS Lett. 247, 453-462 (1989).
38. Pompeiano, M., Palacios, J. M. and Mengod, G. Moiec. Brain Res. 23,163-178 (1994).
39. Yu L. Moiec. Brain Res. 11, 143-149 (1991).
40. Milatovich, A. Hum. molec. Genet. 1, 681-684 (1992).
41. Thomas, I., Power, B., Hudson, P., Schreiber, G, and Dziadek, M. Devi Biol. 128, 415-427 (1988).
42. Orloff, M. J., Williams, H. L. and Pfeiffer, C. C. Proc. Soc. exp. Biol. Med. 70, 254-257 (1949).
43. Blundell, J. E. Am. J. din. Nutr. 55, 155-1598 (1992).
44. Wurtman, J. Neuropsychopharmacology 9, 201-210 (1993).
45. Samanin, R. Naunyn-Schmiedebergs Arch. Pharmac. 308,159-163 (1979).
46. Kennett, G. A. and Curzon, G. Br. J. Pharmac. 103, 2016-2020 (1991).
47. Kitchener, S. J. and Dourish, C. T. Psychopharmacology 113, 369-377 (1994).
48. Parkinson W. L. and Weingarten, H. P. Am. J. Physiol. 259, R829-R835 (1990).
49. Himms-Hagen, J. Front. Neuroendocr. 12, 38-93 (1991).
50. Kilian, M. and Frey, H. H. Neuropharmacology 12, 681-692 (1973).
51. Jobe, P. C., Picchioni, A. L. and Chin, L. Life Sci. 13, 1-13 (1973).
52. Sparks, D. L. and Buckholtz, N. S. Pharmac. Biochem. Behav. 23, 753-757 (1985).
53. Dailey, J. W., Slater, K., Crable, D. J. and Jobe, P. C. Fedn Proc. 46, 2282 (1987).
54. Engel, J. Seizures and Epilepsy (Davis, Philadelphia, 1989).
55. Friedman, J. M. and Leibel, R. L. Cell 69, 217-220 (1992).
56. Flier, J. S. Cell 80, 15-18 (1995).
57. Mansour, S. I., Thomas, K. R. and Capecchi, M. R. Nature 336, 348-352 (1988).
58. Tecott, L., Maricq, A. and Julius, D. Proc. natn. Acad. Sci. U.S.A. 90, 1430-1434 (1993).
59. Brake, A. J., Wagenbach, M. J. and Julius, D. Nature 371, 519-523 (1994).
60. Strack, A. M., Bradbury, M. J. and Dallman, M. F. Am. J. Physiol. 268, R183-191 (1995).