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Volumn 91, Issue 4, 1995, Pages 1161-1174

Hyperhomocysteinemia-induced vascular damage in the minipig: Captopril-hydrochlorothiazide combination prevents elastic alterations

Author keywords

angiotensin; diuretics; hemodynamics; minipigs; rheology

Indexed keywords

CAPTOPRIL; CYSTATHIONINE BETA SYNTHASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HYDROCHLOROTHIAZIDE; METHIONINE;

EID: 0028907052     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.91.4.1161     Document Type: Article
Times cited : (206)

References (67)
  • 1
    • 0003150237 scopus 로고
    • Disorders of transulfuration
    • Standbury JB, Wybgaarden JB, Fredrickson DS, eds. New York, NY: McGraw-Hill Book Co
    • Mudd SH, Levy HL. Disorders of transulfuration. In: Standbury JB, Wybgaarden JB, Fredrickson DS, eds. The Metabolic Basis of Inherited Diseases. New York, NY: McGraw-Hill Book Co; 1978;458-503.
    • (1978) The Metabolic Basis of Inherited Diseases , pp. 458-503
    • Mudd, S.H.1    Levy, H.L.2
  • 2
    • 0005609306 scopus 로고
    • Heterozygosity for homocystinuria in premature peripheral and cerebral occlusive arterial disease
    • Boers GHJ, Smals AG, Trijbels FJ. Heterozygosity for homocystinuria in premature peripheral and cerebral occlusive arterial disease. N Engl J Med. 1985;6:725-730.
    • (1985) N Engl J Med. , vol.6 , pp. 725-730
    • Boers, G.H.J.1    Smals, A.G.2    Trijbels, F.J.3
  • 5
    • 0027523674 scopus 로고
    • Carotid artery intimal-medial wall thickening and plasma homocyst(e)ine in asymptomatic adults: The Atherosclerosis Risk in Communities Study
    • Malinow MR, Nieto JF, Szklo M, Chambless LE, Bond G. Carotid artery intimal-medial wall thickening and plasma homocyst(e)ine in asymptomatic adults: the Atherosclerosis Risk in Communities Study. Circulation. 1993;87:1107-1113.
    • (1993) Circulation , vol.87 , pp. 1107-1113
    • Malinow, M.R.1    Nieto, J.F.2    Szklo, M.3    Chambless, L.E.4    Bond, G.5
  • 6
    • 0014545138 scopus 로고
    • Vascular pathology of homocysteinemia: Implications for the pathogenesis of arteriosclerosis
    • McKully KS. Vascular pathology of homocysteinemia: implications for the pathogenesis of arteriosclerosis. Am J Pathol. 1969; 56:111-121.
    • (1969) Am J Pathol. , vol.56 , pp. 111-121
    • McKully, K.S.1
  • 7
    • 0014859783 scopus 로고
    • Production of atherosclerosis by homocysteinemia
    • McCully KS, Ragsdale BD. Production of atherosclerosis by homocysteinemia. Am J Pathol. 1970;61:1-8.
    • (1970) Am J Pathol. , vol.61 , pp. 1-8
    • McCully, K.S.1    Ragsdale, B.D.2
  • 8
  • 9
    • 0018743549 scopus 로고
    • Experimental homocystinemia, endothelial lesions and thrombosis
    • Hladovec J. Experimental homocystinemia, endothelial lesions and thrombosis. Blood Vessels. 1979;16:202-205.
    • (1979) Blood Vessels , vol.16 , pp. 202-205
    • Hladovec, J.1
  • 10
    • 0017197285 scopus 로고
    • Homocystine-induced arteriosclerosis: The role of endothelial cell injury and platelet response in its genesis
    • Harker LA, Ross R, Slichter SJ, Scott CR. Homocystine-induced arteriosclerosis: the role of endothelial cell injury and platelet response in its genesis. J Clin Invest. 1976;58:731-741.
    • (1976) J Clin Invest. , vol.58 , pp. 731-741
    • Harker, L.A.1    Ross, R.2    Slichter, S.J.3    Scott, C.R.4
  • 11
    • 0018858624 scopus 로고
    • Homocysteine-induced endothelial cell injury in vitro: A model for the study of vascular injury
    • Wall RT, Harlan JM. Homocysteine-induced endothelial cell injury in vitro: a model for the study of vascular injury. Thromb Res. 1980;18:113-121.
    • (1980) Thromb Res. , vol.18 , pp. 113-121
    • Wall, R.T.1    Harlan, J.M.2
  • 12
    • 0019979605 scopus 로고
    • Experimental homocysteinemia in pigs: Comparison with studies in sixteen homocystinuric patients
    • Reddy GSRR, Wilcken DEL. Experimental homocysteinemia in pigs: comparison with studies in sixteen homocystinuric patients. Metabolism. 1982;31:778-783.
    • (1982) Metabolism , vol.31 , pp. 778-783
    • Reddy, G.S.R.R.1    Wilcken, D.E.L.2
  • 13
    • 0019947277 scopus 로고
    • Homocysteine thiolactone and experimental homocysteinemia
    • Dudman NPB, Wilcken DEL. Homocysteine thiolactone and experimental homocysteinemia. Biochem Med. 1992;27:244-253.
    • (1992) Biochem Med. , vol.27 , pp. 244-253
    • Dudman, N.P.B.1    Wilcken, D.E.L.2
  • 14
    • 0020315230 scopus 로고
    • 6 deficiency: A model for the study of cystathionine β-synthase deficiency
    • 6 deficiency: a model for the study of cystathionine β-synthase deficiency. J Nutr. 1982;112:1264-1272.
    • (1982) J Nutr. , vol.112 , pp. 1264-1272
    • Smolin, L.A.1    Benevenga, N.J.2
  • 15
    • 0006791894 scopus 로고
    • Pathogenesis of experimental arteriosclerosis in pyridoxine deficiency with notes on similarities to human arteriosclerosis
    • Rinehart JF, Greenberg LD. Pathogenesis of experimental arteriosclerosis in pyridoxine deficiency with notes on similarities to human arteriosclerosis. Arch Pathol. 1951;51:12-18.
    • (1951) Arch Pathol. , vol.51 , pp. 12-18
    • Rinehart, J.F.1    Greenberg, L.D.2
  • 16
    • 0017407928 scopus 로고
    • Failure to produce atherosclerosis in Macaca radiata on a high-methionine, high-fat, pyridoxine-deficient diet
    • Krishnaswamy K, Rao SB. Failure to produce atherosclerosis in Macaca radiata on a high-methionine, high-fat, pyridoxine-deficient diet. Atherosclerosis. 1977;27:253-258.
    • (1977) Atherosclerosis , vol.27 , pp. 253-258
    • Krishnaswamy, K.1    Rao, S.B.2
  • 17
    • 0017146133 scopus 로고
    • Nitrogen retention in men fed isolated soybean protein supplemented with L-methionine, D-methionine, N-acetyl-L-methionine or inorganic sulfate
    • Zezulka AY, Calloway DH. Nitrogen retention in men fed isolated soybean protein supplemented with L-methionine, D-methionine, N-acetyl-L-methionine or inorganic sulfate. J Nutr. 1976; 106:1286-1291.
    • (1976) J Nutr. , vol.106 , pp. 1286-1291
    • Zezulka, A.Y.1    Calloway, D.H.2
  • 19
    • 0025673878 scopus 로고
    • Plasma amino acids and cholesterol following consumption of dietary casein or soy protein in minipigs
    • Hagemeister H, Scholz-Ahrens KE, Schulte-Coerne H, Barth CA. Plasma amino acids and cholesterol following consumption of dietary casein or soy protein in minipigs. J Nutr. 1990; 120:1305-1311.
    • (1990) J Nutr. , vol.120 , pp. 1305-1311
    • Hagemeister, H.1    Scholz-Ahrens, K.E.2    Schulte-Coerne, H.3    Barth, C.A.4
  • 22
    • 0021369919 scopus 로고
    • Alterations in prostacyclin and prostaglandin E2 production: Correlation with changes in human aortic atherosclerosis disease
    • Rolland PH, Jouve R, Pellegrin E, Mercier C, Serradimigni A. Alterations in prostacyclin and prostaglandin E2 production: correlation with changes in human aortic atherosclerosis disease. Arteriosclerosis. 1984;4:70-78.
    • (1984) Arteriosclerosis , vol.4 , pp. 70-78
    • Rolland, P.H.1    Jouve, R.2    Pellegrin, E.3    Mercier, C.4    Serradimigni, A.5
  • 23
    • 0026488910 scopus 로고
    • Ultrastructure appearance of atherosclerosis in human and experimentally-induced animal models
    • Nakamura H, Ohtsubo K. Ultrastructure appearance of atherosclerosis in human and experimentally-induced animal models. Electr Microsc Rev. 1992;5:129-170.
    • (1992) Electr Microsc Rev. , vol.5 , pp. 129-170
    • Nakamura, H.1    Ohtsubo, K.2
  • 28
    • 0023943778 scopus 로고
    • Effects of chronic inhibition of converting enzyme on mechanical and structural properties of arteries in rat renovascular hypertension
    • Levy BI, Michel JBB, Salzmann JL, Azizi M, Poitevin P, Safar ME, Camillieri JP. Effects of chronic inhibition of converting enzyme on mechanical and structural properties of arteries in rat renovascular hypertension. Circ Res. 1988;63:227-239.
    • (1988) Circ Res. , vol.63 , pp. 227-239
    • Levy, B.I.1    Michel, J.B.B.2    Salzmann, J.L.3    Azizi, M.4    Poitevin, P.5    Safar, M.E.6    Camillieri, J.P.7
  • 29
    • 85047680745 scopus 로고
    • Estimation of forearm arterial compliance in normal and hypertensive men from simultaneous pressure and flow measurements in the brachial artery, using a pulsed Doppler device and a first-order arterial model during diastole
    • Simon AC, Lurent S, Levenson JA, Bouthier JE, Safar ME. Estimation of forearm arterial compliance in normal and hypertensive men from simultaneous pressure and flow measurements in the brachial artery, using a pulsed Doppler device and a first-order arterial model during diastole. Cardiovasc Res. 1983;17:331-338.
    • (1983) Cardiovasc Res. , vol.17 , pp. 331-338
    • Simon, A.C.1    Lurent, S.2    Levenson, J.A.3    Bouthier, J.E.4    Safar, M.E.5
  • 33
    • 0026806848 scopus 로고
    • Chronic antihypertensive treatment with captopril plus hydrochlorothiazide improves aortic distensibility in the spontaneously hypertensive rat
    • Chillon JM, Capdeville-Atkinson C, Lartaud I, Guillou J, Mertès PM, Atkinson J. Chronic antihypertensive treatment with captopril plus hydrochlorothiazide improves aortic distensibility in the spontaneously hypertensive rat. Br J Pharmacol. 1992;107:710-714.
    • (1992) Br J Pharmacol. , vol.107 , pp. 710-714
    • Chillon, J.M.1    Capdeville-Atkinson, C.2    Lartaud, I.3    Guillou, J.4    Mertès, P.M.5    Atkinson, J.6
  • 34
    • 0023832738 scopus 로고
    • 12 deficiency than in heterozygosity for homocystinuria due to cystathionine β-synthase deficiency
    • 12 deficiency than in heterozygosity for homocystinuria due to cystathionine β-synthase deficiency. Metabolism. 1988;37:175-178.
    • (1988) Metabolism , vol.37 , pp. 175-178
    • Brattstrom, L.1    Israelsson, B.2    Lindgarde, F.3    Hutberg, B.4
  • 35
    • 0023554618 scopus 로고
    • Fixed-dose combination medications for the treatment of hypertension: A critical review
    • Oster JR, Epstein M. Fixed-dose combination medications for the treatment of hypertension: a critical review. J Clin Hypertens. 1987;3:278-293.
    • (1987) J Clin Hypertens. , vol.3 , pp. 278-293
    • Oster, J.R.1    Epstein, M.2
  • 36
    • 0026738088 scopus 로고
    • Efficiency of dietary methionine utilization by young pigs
    • Chung TK, Baker DH. Efficiency of dietary methionine utilization by young pigs. J Nutr. 1992;122:1862-1869.
    • (1992) J Nutr. , vol.122 , pp. 1862-1869
    • Chung, T.K.1    Baker, D.H.2
  • 37
    • 0025362827 scopus 로고
    • Methionine metabolism in mammals
    • Finkelstein JD. Methionine metabolism in mammals. J Nutr Biochem. 1990;1:228-237.
    • (1990) J Nutr Biochem. , vol.1 , pp. 228-237
    • Finkelstein, J.D.1
  • 38
    • 0027161812 scopus 로고
    • Measurement of angiotensin I converting enzyme inhibition in the heart
    • Kinoshita A, Urata H, Bumpus FM, Husain A. Measurement of angiotensin I converting enzyme inhibition in the heart. Circ Res. 1993;73:51-60.
    • (1993) Circ Res. , vol.73 , pp. 51-60
    • Kinoshita, A.1    Urata, H.2    Bumpus, F.M.3    Husain, A.4
  • 39
    • 0023929623 scopus 로고
    • Vasodilation by calcitonin gene-related peptide and substance P: A comparison of their effects on resistance and capacitance vessels of human forearms
    • McEwan JR, Benjamin N, Larkin S, Fuller RW, Doollery CT, MacIntyre I. Vasodilation by calcitonin gene-related peptide and substance P: a comparison of their effects on resistance and capacitance vessels of human forearms. Circulation. 1988;77:1072-1080.
    • (1988) Circulation , vol.77 , pp. 1072-1080
    • McEwan, J.R.1    Benjamin, N.2    Larkin, S.3    Fuller, R.W.4    Doollery, C.T.5    MacIntyre, I.6
  • 40
    • 0024363876 scopus 로고
    • Effects of SIN-1 on peripheral hemodynamics and viscoelastic properties of aorta in anesthetized rabbits
    • Friggi A, Bodard H, Berenger FP, Esclapez F, Rolland PH. Effects of SIN-1 on peripheral hemodynamics and viscoelastic properties of aorta in anesthetized rabbits. Cardiovasc Drugs Ther. 1989; 3:445-448.
    • (1989) Cardiovasc Drugs Ther. , vol.3 , pp. 445-448
    • Friggi, A.1    Bodard, H.2    Berenger, F.P.3    Esclapez, F.4    Rolland, P.H.5
  • 41
    • 0018377323 scopus 로고
    • Effects of age on pressure-diameter and elastic stiffness-stress relationships in unanesthetized sheep
    • Pagani M, Mirsky I, Baig H, Manders WT, Kerkhof P, Vatner SF. Effects of age on pressure-diameter and elastic stiffness-stress relationships in unanesthetized sheep. Circ Res. 1979;44:420-429.
    • (1979) Circ Res. , vol.44 , pp. 420-429
    • Pagani, M.1    Mirsky, I.2    Baig, H.3    Manders, W.T.4    Kerkhof, P.5    Vatner, S.F.6
  • 42
    • 78650519144 scopus 로고
    • Amino acid metabolism in swine: Applicability to normal and altered amino acid metabolism in humans
    • Tmumbleson ME, ed. New York, NY: Plenum Press
    • Benevenga NJ. Amino acid metabolism in swine: applicability to normal and altered amino acid metabolism in humans. In: Tmumbleson ME, ed. Swine in Biomedical Research. New York, NY: Plenum Press; 1986:1017-1030.
    • (1986) Swine in Biomedical Research , pp. 1017-1030
    • Benevenga, N.J.1
  • 43
    • 0027468536 scopus 로고
    • Circulating lipid hydroperoxide levels in human hyperhomocysteinemia: Relevance to development of arteriosclerosis
    • Dudman NPB, Wilcken DEL, Stocker R. Circulating lipid hydroperoxide levels in human hyperhomocysteinemia: relevance to development of arteriosclerosis. Arterioscler Thromb. 1993; 13:512-516.
    • (1993) Arterioscler Thromb. , vol.13 , pp. 512-516
    • Dudman, N.P.B.1    Wilcken, D.E.L.2    Stocker, R.3
  • 44
  • 45
    • 0027531427 scopus 로고
    • Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen
    • Stamler JS, Osborne JA, Jaraki O, Rabbani LE, Mullins M, Singel D, Loscalzo J. Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen. J Clin Invest. 1993;91:308-318.
    • (1993) J Clin Invest. , vol.91 , pp. 308-318
    • Stamler, J.S.1    Osborne, J.A.2    Jaraki, O.3    Rabbani, L.E.4    Mullins, M.5    Singel, D.6    Loscalzo, J.7
  • 46
    • 0026345948 scopus 로고
    • Inhibition of thrombomodulin surface expression and protein C activation by the thrombogenic agent homocysteine
    • Lentz SR, Sadler JE. Inhibition of thrombomodulin surface expression and protein C activation by the thrombogenic agent homocysteine. J Clin Invest. 1991;88:1906-1912.
    • (1991) J Clin Invest. , vol.88 , pp. 1906-1912
    • Lentz, S.R.1    Sadler, J.E.2
  • 47
    • 0001768423 scopus 로고
    • The influence of vascular smooth muscle on the viscoelastic properties of blood vessels
    • Bergel DH, ed. London, UK: Academic Press
    • Gow BS. The influence of vascular smooth muscle on the viscoelastic properties of blood vessels. In: Bergel DH, ed. Cardiovascular Fluid Dynamics. London, UK: Academic Press; 1972:65-110.
    • (1972) Cardiovascular Fluid Dynamics , pp. 65-110
    • Gow, B.S.1
  • 48
    • 0000564597 scopus 로고
    • Studies on the elastic properties of human isolated aorta
    • Hallock P, Benson IC. Studies on the elastic properties of human isolated aorta. J Clin Invest. 1937;16:595-604.
    • (1937) J Clin Invest. , vol.16 , pp. 595-604
    • Hallock, P.1    Benson, I.C.2
  • 49
    • 77049188483 scopus 로고
    • Relation of structure-function in tissues of the wall of blood vessels
    • Burton AC. Relation of structure-function in tissues of the wall of blood vessels. Physiol Rev. 1954;34:619-642.
    • (1954) Physiol Rev. , vol.34 , pp. 619-642
    • Burton, A.C.1
  • 51
    • 0027254447 scopus 로고
    • Evidence for sensory nerve involvement in cutaneous reactive hyperemia in humans
    • Larkin SW, Williams TJ. Evidence for sensory nerve involvement in cutaneous reactive hyperemia in humans. Circ Res. 1993; 73:147-154.
    • (1993) Circ Res. , vol.73 , pp. 147-154
    • Larkin, S.W.1    Williams, T.J.2
  • 53
    • 0015621283 scopus 로고
    • Changes in bradykinin level in coronary sinus blood after experimental occlusion of a coronary artery
    • Kimura E, Hashimoto K, Furukawa S, Hayakawa H. Changes in bradykinin level in coronary sinus blood after experimental occlusion of a coronary artery. Am Heart J. 1973;85:635-647.
    • (1973) Am Heart J. , vol.85 , pp. 635-647
    • Kimura, E.1    Hashimoto, K.2    Furukawa, S.3    Hayakawa, H.4
  • 54
    • 0005238252 scopus 로고
    • The fine structure of human atherosclerotic lesions
    • Geer JC, McGill HC Jr, Strong JP. The fine structure of human atherosclerotic lesions. Am J Pathol. 1961;38:263-287.
    • (1961) Am J Pathol. , vol.38 , pp. 263-287
    • Geer, J.C.1    McGill Jr., H.C.2    Strong, J.P.3
  • 55
    • 0025817390 scopus 로고
    • Proliferation of smooth muscle cells after vascular injury is inhibited by an antibody against fibroblast growth factor
    • Lindner V, Reidy MA. Proliferation of smooth muscle cells after vascular injury is inhibited by an antibody against fibroblast growth factor. Proc Natl Acad Sci U S A. 1991;88:3739-3743.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 3739-3743
    • Lindner, V.1    Reidy, M.A.2
  • 56
    • 0026534274 scopus 로고
    • Platelet-derived growth factor promotes smooth muscle migration and intimal thickening in a rat model of balloon angioplasty
    • Jawien AD, Bowen-Pope DF, Lindner V, Schwartz SM, Clowes AW. Platelet-derived growth factor promotes smooth muscle migration and intimal thickening in a rat model of balloon angioplasty. J Clin Invest. 1992;89:507-511.
    • (1992) J Clin Invest. , vol.89 , pp. 507-511
    • Jawien, A.D.1    Bowen-Pope, D.F.2    Lindner, V.3    Schwartz, S.M.4    Clowes, A.W.5
  • 57
    • 0027261204 scopus 로고
    • Role of endogenous platelet-derived growth factor in arterial smooth muscle cell migration after balloon catheter injury
    • Jackson CL, Raines EW, Ross R, Reidy MA. Role of endogenous platelet-derived growth factor in arterial smooth muscle cell migration after balloon catheter injury. Arterioscler Thromb. 1993;13:1218-1226.
    • (1993) Arterioscler Thromb. , vol.13 , pp. 1218-1226
    • Jackson, C.L.1    Raines, E.W.2    Ross, R.3    Reidy, M.A.4
  • 58
    • 0025125620 scopus 로고
    • Angiotensin converting enzyme inhibitors and moderate hypertension
    • McAreavey D, Robertson JIS. Angiotensin converting enzyme inhibitors and moderate hypertension. Drugs. 1990;40:326-345.
    • (1990) Drugs , vol.40 , pp. 326-345
    • McAreavey, D.1    Robertson, J.I.S.2
  • 59
    • 0021952579 scopus 로고
    • Differing dosages of captopril and hydrochlorothiazide in the treatment of hypertension: Long-term effects on metabolic values and intracellular electrolytes
    • Costa FV, Borghi C, Boschi S, Ambrosiani E. Differing dosages of captopril and hydrochlorothiazide in the treatment of hypertension: long-term effects on metabolic values and intracellular electrolytes. J Cardiovasc Pharmacol. 1985;7(suppl 1):S70-S76.
    • (1985) J Cardiovasc Pharmacol. , vol.7 , Issue.1 SUPPL.
    • Costa, F.V.1    Borghi, C.2    Boschi, S.3    Ambrosiani, E.4
  • 62
    • 0027155562 scopus 로고
    • Role of kinins and nitric oxide in the effects of angiotensin converting enzyme inhibitors on neointima formation
    • Farhy RD, Carretero OA, Ho KL, Scicli AG. Role of kinins and nitric oxide in the effects of angiotensin converting enzyme inhibitors on neointima formation. Circ Res. 1993;72:1202-1210.
    • (1993) Circ Res. , vol.72 , pp. 1202-1210
    • Farhy, R.D.1    Carretero, O.A.2    Ho, K.L.3    Scicli, A.G.4
  • 63
    • 0023935656 scopus 로고
    • Large conduit arteries in hypertension: Role of the vascular renin-angiotensin system
    • Dzau VJ, Safar ME. Large conduit arteries in hypertension: role of the vascular renin-angiotensin system. Circulation. 1988;77:947-954.
    • (1988) Circulation , vol.77 , pp. 947-954
    • Dzau, V.J.1    Safar, M.E.2
  • 64
    • 0024407452 scopus 로고
    • Inhibitors of angiotensin-converting enzyme prevent myointimal proliferation after vascular injury
    • Powell JS, Clozel JP, Muller RK, Kuhn H, Hefti F, Hosang M, Baumgartner HR. Inhibitors of angiotensin-converting enzyme prevent myointimal proliferation after vascular injury. Science 1989;245:186-188.
    • (1989) Science , vol.245 , pp. 186-188
    • Powell, J.S.1    Clozel, J.P.2    Muller, R.K.3    Kuhn, H.4    Hefti, F.5    Hosang, M.6    Baumgartner, H.R.7
  • 66
    • 0026573059 scopus 로고
    • Angiotensin-II stimulates the proliferation and biosynthesis of type-I collagen in cultured murine mesangial cells
    • Wolf G, Haberstroh U, Neilson EG. Angiotensin-II stimulates the proliferation and biosynthesis of type-I collagen in cultured murine mesangial cells. Am J Pathol. 1992;140:95-107.
    • (1992) Am J Pathol. , vol.140 , pp. 95-107
    • Wolf, G.1    Haberstroh, U.2    Neilson, E.G.3
  • 67
    • 0019491077 scopus 로고
    • Elastin structure, biosynthesis, and relation to disease states
    • Sandberg LB, Soskel NT, Leslie JG. Elastin structure, biosynthesis, and relation to disease states. N Engl J Med. 1981;304:566-579.
    • (1981) N Engl J Med. , vol.304 , pp. 566-579
    • Sandberg, L.B.1    Soskel, N.T.2    Leslie, J.G.3


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