Structure-Activity Studies of 2,3,4,4a,5,9b-Hexahydroindeno[1,2-c]pyridines as Antispermatogenic Agents for Male Contraception

Journal of Medicinal Chemistry

Volumn 38, Issue 5, 1995, Pages 753-763

  Cook, C Edgar ^a   Wani, Mansukh C ^a   Jump, Joseph M ^a   Lee, Yue W ^a   Fail, Patricia A ^a   Anderson, Stephanie A ^a   Gu, Yu Q ^b   Petrow, Vladimir ^c  

^a RTI INTERNATIONAL   (United States)

^b UNIVERSITY OF TOLEDO   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 ETHYL 2,3,4,4A,5,9B HEXAHYDRO 5 [4 (HYDROXYMETHYL)PHENYL] 7 METHYL 1H INDENO[1,2 C]PYRIDINE; 2 ETHYL 2,3,4,4A,5,9B HEXAHYDRO 7 METHYL 5 (4 TOLYL) 1H INDENO[1,2 C]PYRIDINE; 2 ETHYL 5 (4 FORMYLPHENYL) 2,3,4,4A,5,9B HEXAHYDRO 7 METHYL 1H INDENO[1,2 C]PYRIDINE; 5 (4 CARBOMETHOXYPHENYL) 2 ETHYL 2,3,4,4A,5,9B HEXAHYDRO 7 METHYL 1H INDENO[1,2 C]PYRIDINE; 5 (4 CARBOXYPHENYL) 2 ETHYL 2,3,4,4A,5,9B HEXAHYDRO 7 METHYL 1H INDENO[1,2 C]PYRIDINE; ANTISPERMATOGENIC AGENT; FOLLITROPIN; LUTEINIZING HORMONE; PYRIDINE DERIVATIVE; RTI 4587 030; RTI 4587 054; RTI 4587 055; RTI 4587 056; SDZ 20 438; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG EFFICACY; MALE; MOUSE; NONHUMAN; ORAL CONTRACEPTION; ORAL DRUG ADMINISTRATION; SPERMATOGENESIS; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; TESTIS WEIGHT;

ADMINISTRATION, ORAL; ANIMAL; ANTISPERMATOGENIC AGENTS; FERTILITY; INJECTIONS, SUBCUTANEOUS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MICE; ORGAN WEIGHT; PYRIDINES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, U.S. GOV'T, P.H.S.; TESTIS;

EID: 0028905629     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00005a003     Document Type: Article

References (12)

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