Gains and Losses of DNA Sequences in Osteosarcomas by Comparative Genomic Hybridization

Cancer Research

Volumn 55, Issue 6, 1995, Pages 1334-1338

  Tarkkanen, Maija ^a   Knuutila, Sakari ^a   Böhling, Tom ^a   Karhu, Ritva ^b   Kallioniemi, Anne ^b   Hyytinen, Eya ^b   Kallioniemi, Olli P ^b   Elomaa, Inkeri ^c   Kivioja, Aarne H ^c   Karaharju, Erkki ^c   Nevalainen, Juha ^d  

^a UNIVERSITY OF HELSINKI   (Finland)

^b TAMPERE UNIVERSITY HOSPITAL   (Finland)

^c HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^d TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DNA;

ARTICLE; CHROMOSOMAL LOCALIZATION; CHROMOSOME 10P; CHROMOSOME 12Q; CHROMOSOME 2Q; CHROMOSOME 6Q; CHROMOSOME 8P; CHROMOSOME 8Q; CHROMOSOME XP; CONTROLLED STUDY; DNA HYBRIDIZATION; GENE AMPLIFICATION; GENE LOCATION; GENE LOSS; HUMAN; HUMAN TISSUE; OSTEOSARCOMA; PRIORITY JOURNAL;

CHROMOSOME ABERRATIONS; CHROMOSOME DELETION; GENE AMPLIFICATION; HUMAN; NUCLEIC ACID HYBRIDIZATION; OSTEOSARCOMA; SUPPORT, NON-U.S. GOV'T;

EID: 0028905350     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Biegel, J. A., Womer, R. B., and Emanuel, B. S. Complex karyotypes in a series of pediatric osteosarcomas. Cancer Genet. Cytogenet., 38: 89–100, 1989.
2. Hoogerwerf, W. A., Hawkins, A. L., Perlman, E. J., and Griffin, C. A. Chromosome analysis of nine osteosarcomas. Genes Chromosomes Cancer, 9; 88–92,1994.
3. Mertens, F., Mandahl, N., Orndal, C., Baldetorp, B., Bauer, H. C. F., Rydholm, A., Wiebe, T., Willén, H., Akerman, M., Heim, S., and Mitelman, F. Cytogenetic findings in 33 osteosarcomas. Int. J. Cancer, 55: 44–50, 1993.
4. Tarkkanen, M., Kaipainen, A., Karaharju, E., Bdhling, T., Szymanska, J., Helid, H., Kivioja, A., Elomaa, I., and Knuutila, S. Cytogenetic study of 249 consecutive patients examined for a bone tumor. Cancer Genet. Cytogenet., 68: 1–21, 1993.
5. Scheffer, H., Kruize, Y. C. M., Osinga, J., Kuiken, G., Oosterhuis, J. W., Leeuw, J. A., Schraffordt Koops, H., and Buys, C. H. C. M. Complete association of loss of heterozygosity of chromosomes 13 and 17 in osteosarcoma. Cancer Genet. Cytogenet., 53: 45–55, 1991.
6. Toguchida, J., Ishizaki, K., Sasaki, M. S., Ikenaga, M., Sugimoto, M., Kotoura, Y., and Yamamuro, T. Chromosomal reorganization for the expression of recessive mutation of retinoblastoma susceptibility gene in the development of osteosarcoma. Cancer Res., 48: 3939–3943, 1988.
7. Toguchida, J., Ishizaki, K., Nakamura, Y., Sasaki, M. S., Ikenaga, M., Kato, M., Sugimoto, M., Kotoura, Y., and Yamamuro, T. Assignment of common allele loss in osteosarcoma to the subregion 17pl3. Cancer Res., 49: 6247–6251, 1989.
8. Yamaguchi, T., Toguchida, J., Yamamuro, T., Kotoura, Y., Takada, N., Kawaguchi, N., Kaneko, Y., Nakamura, Y., Sasaki, M. S., and Ishizaki, K. Allelotype analysis in osteosarcomas: frequent allele loss on 3q, 13q, 17p, and 18q. Cancer Res., 52: 2419–2423, 1992.
9. Miller, C. W., Aslo, A., Tsay, C., Slamon, D., Ishizaki, K., Toguchida, J., Yamamuro, T., Lampkin, B., and Koeffler, H. P. Frequency and structure of p53 rearrangements in human osteosarcoma. Cancer Res., 50: 7950–7954, 1990.
10. Devilee, P., van Vliet, M., van Sloun, P., Kuipers Dijkshoorn, N., Hermans, J., Pearson, P. L., and Cornelisse, C. J. Allelotype of human breast carcinoma: a second major site for loss of heterozygosity is on chromosome 6q. Oncogene, 6:1705–1711, 1991.
11. Ladanyi, M., Cha, C., Lewis, R., Jhanwar, S. C., Huvos, A. G., and Healey, J. H. MDM2 gene amplification in metastatic osteosarcoma. Cancer Res., 53: 16–18, 1993.
12. Oliner, J. D., Kinzler, K. W., Meltzer, P. S., George, D. L., and Vogelstein, B. Amplification of a gene encoding a p53-associated protein in human sarcomas. Nature (Lond.), 358: 80–83, 1992.
13. Khatib, Z. A., Matsushime, H., Valentine, M., Shapiro, D. N., Sherr, C. J., and Look, A. T. Coamplification of the CDK4 gene with MDM2 and GU in human sarcomas. Cancer Res., 53: 5535–5541, 1993.
14. Roberts, W. M., Douglass, E. C., Peiper, S. C., Houghton, P. J., and Look, A. T. Amplification of the gU gene in childhood sarcomas. Cancer Res., 49:5407–5413,1989.
15. Barrios, C., Castresana, J. S., Ruiz, J., and Kreicbergs, A. Amplification of c-myc oncogene and absence of c-Ha-ras point mutation in human bone sarcoma. J. Orthop. Res., 11: 556–563, 1993.
16. Ladanyi, M., Park, C. K., Lewis, R., Jhanwar, S. C., Healey, J. H., and Huvos, A. G. Sporadic amplification of the MYC gene in human osteosarcomas. Diagn. Mol. Pathol., 2: 163–167,1993.
17. Kallioniemi, A., Kallioniemi, O.-P., Sudar, D., Rutovitz, D., Gray, J. W., Waldman, F., and Pinkel, D. Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors. Science (Washington, DC), 258: 818–821, 1992.
18. Kallioniemi, A., Kallioniemi, O.-P., Piper, J., Tanner, M., Stokke, T., Chen, L., Smith, H. S., Pinkel, D., Gray, J. W., and Waldman, F. M. Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization. Proc. Natl. Acad. Sci. USA, 91: 2156–2160, 1994.
19. Kallioniemi, O.-P., Kallioniemi, A., Piper, J., Isola, J., Waldman, F. M., Gray, J. W., and Pinkel, D. Optimizing comparative genomic hybridization for analysis of DNA sequence copy number changes in solid tumors. Genes Chromosomes Cancer 10: 231–243, 1994.
20. Piper, J., Rutovitz, D., Sudar, D., Kallioniemi, A., Kallioniemi, O.-P., Waldman, F. M., Gray, J. W., and Pinkel, D. Computer image analysis of comparative genomic hybridization. Cytometry, in press, 1995.
21. Hyytinen, E., Visakorpi, T., Kallioniemi, A., Kallioniemi, O.-P., and Isola, J. J. Improved technique for analysis of formalin-fixed, paraffin-embedded tumors by fluorescence in situ hybridization. Cytometry, 16: 93–99, 1994.
22. Ried, T., Petersen, I., Holtgreve-Grez, R., Speicher, M. R., Schrock, E., du Manoir, S., and Cremer, T. Mapping of multiple DNA gains and losses in primary small cell lung carcinomas by comparative genomic hybridization. Cancer Res., 54: 1801–1806, 1994.
23. Tanner, M. M., Tirkkonen, M., Kallioniemi, A., Collins, C., Stokke, T., Karhu, R., Kowbel, D., Shadravan, F., Hintz, M., Kuo, W.-L., Waldman, F. M., Isola, J. J., Gray, J. W., and Kallioniemi, O.-P. Increased copy number at 20ql3 in breast cancer: defining the critical region and exclusion of candidate genes. Cancer Res., 54: 4257–4260, 1994.
24. du Manoir, S., Speicher, M. R., Joos, S., Schrock, E., Popp, S., Ddhner, H., Kovacs, G., Robert-Nicoud, M., Lichter, P., and Cremer, T. Detection of complete and partial chromosome gains and losses by comparative genomic in situ hybridization. Hum. Genet., 90: 590–610, 1993.
25. Bijlsma, E. K., Leenstra, S., Westerveld, A., Bosch, D. A., and Hulsebos, T. J. M. Amplification of the anonymous marker D17S67 in malignant astrocytomas. Genes Chromosomes Cancer, 9: 148–152, 1994.
26. Bergerheim, U. S. R., Kunimi, K., Collins, V. P., and Ekman, P. Deletion mapping of chromosomes 8, 10, and 16 in human prostatic carcinoma. Genes Chromosomes Cancer, 3: 215–220, 1991.
27. Vogelstein, B., Fearon, E. R., Kern, S. E., Hamilton, S. R., Preisinger, A. C., Nakamura, Y., and White, R. Allelotype of colorectal carcinomas. Science (Washington DC), 244: 207–211, 1989.