Behavioral, histological, and neurochemical effects of nickel (II) on the rat olfactory system

Toxicology and Applied Pharmacology

Volumn 130, Issue 2, 1995, Pages 209-220

  Evans, James E ^a   Miller, Marian L ^b   Andringa, Anastasia ^b   Hastings, Lloyd ^b  

^a OHIO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF CINCINNATI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARNOSINE; NICKEL; NICKEL SULFATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR; CONTROLLED STUDY; HISTOLOGY; INHALATION; MALE; NEUROCHEMISTRY; NONHUMAN; OLFACTORY SYSTEM; RAT;

ADMINISTRATION, INHALATION; ANIMAL; ATMOSPHERE EXPOSURE CHAMBERS; BODY WEIGHT; CARNOSINE; EPITHELIUM; MALE; MICROSCOPY, ELECTRON; NICKEL; OLFACTORY PATHWAYS; ORGAN WEIGHT; RATS; SENSORY THRESHOLDS; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0028904416     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1006/taap.1995.1026     Document Type: Article

References (58)

1. Adams, R. G., and Crabtree, N. (1961). Anosmia in alkaline battery workers. Br. J. Ind. Med. 18, 216-221.
2. American Conference of Governmental Hygienists, Inc. (ACGHI) (1991). Nickel. In Documentation of the Threshold Limit Values and Biological Exposure Indices, 6th ed., pp. 1070-1075. ACGHI, Cincinnati, OH.
3. Amoore, J. E., and Hautala, E. (1983). Odor as an aid to chemical safety: Odor thresholds compared with threshold limit values and volatilities for 214 industrial chemicals in air and water dilution. J. Appl. Toxicol. 3(6), 272-290.
4. Amoore, J. E. (1986). Effects of chemical exposure on olfaction in humans. In Toxicology of the Nasal Passages (C. S. Barrow, Ed.), pp. 155-190. Hemisphere Publishing, Washington.
5. Athar, M., Hasan, S. K., and Srivastava, R. C. (1987a). Evidence for the involvment of hyroxyl radical in nickel mediated enhancement of lipid peroxidation: Implications for nickel carcinogenesis. Biochem. Biophys. Res. Commun. 147, 1276-1281.
6. Athar, M., Hasan, S. K., and Srivastava, R. C. (1987b). Role of glutathione metabolizing enzymes in nickel mediated induction of hepatic glutathione. Res. Commun. Chem. Pathol. Pharmacol. 57, 421-424.
7. Benignus, V. A., and Prah, J. D. (1982). Olfaction: Anatomy, physiology and behavior. Environ. Health Perspect. 44, 15-21.
8. Benson, J. M., Henderson, R. F., McClellan, R. O., Hanson, R. L., and Rebar, A. H. (1986). Comparative acute toxicity of four nickel compounds to F344 rat lung. Fundam. Appl. Toxicol. 7, 340-347.
9. Benson, J. M., Carpenter, R. L., Hahn, F. F., Haley, P. J., Hanson, R. L., Hobbs, C. H., Pickrell, J. A., and Dunnick, J. K. (1987). Comparative inhalation toxicity of nickel subsulfide to F344/N rats and B6C3F, mice exposed for 12 days. Fundam. Appl. Toxicol. 9, 251-265.
10. Benson, J. M., Burt, D. G., Carpenter, R. L., Eidson, A. F., Hahn, F. F., Haley, P. J., Hanson, R. L., Hobbs, C. H., Pickrell, J. A., and Dunnick, J. K. (1988). Comparative inhalation toxicity of nickel sulfate to F344/N rats and B6C3F, mice exposed for twelve days. Fundam. Appl. Toxicol. 10, 164-178.
11. Benson, J. M., Burt, D. G., Cheng, Y. S., Hahn, F. F., Haley, P. J., Henderson, R. F., Hobbs, C. H., Pickrell, J. A., and Dunnick, J. K. (1989). Biochemical responses of rat and mouse lung to inhaled nickel compounds. Toxicology 57, 255-266.
12. Biffo, S., Grille M., and Margolis, F. L. (1990). Cellular localization of carnosine-like and anserine-like immunoreactivities in rodent and avian central nervous system. Neuroscience 35, 637-651.
13. Bosta, M., Abbracchio, M. P., and Simmons-Hansen, J. (1981). Factors influencing the phagocytosis, neoplastic transformation and cytotoxicity of particulate nickel compounds in tissue culture systems. Toxicol. Appl. Pharmacol. 60, 313-323.
14. Burd, G. D., Davis, B. J., Macrides, F., Grillo, M, and Margolis, F. L. (1982). Carnosine in primary afferents of the olfactory system: An autoradiographic and biochemical study. J. Neurosci. 2, 244-255.
15. Cancalon, P. (1982). Degeneration and regeneration of olfactory cells induced by ZnS04 and other chemicals. Tissue Cell 14, 717-733.
16. Carr, V. M., Farbman, A. I., Colletti, L. M., and Morgan, J. 1. (1991). Identification of a new non-neuronal cell type in rat olfactory epithelium. Neuroscience 45, 433-449.
17. Coogan, T. P., Latta, D. M., Snow, E. T., and Costa, M. (1989). Toxicity and carcinogenicity of nickel compounds. CRC Crii. Rev. Toxiol. 19(4), 341-384.
18. Dahl, A. R., and Hadley, W. M. (1991). Nasal cavity enzymes involved in xenobiotic metabolism: Effects on the toxicity of inhalants. CRC Crit. Rev. Toxicol. 21, 345-372.
19. Doty, R.L, Bartoshuk, L. M., and Snow, J. B. Jr. (1991). Causes of olfactory and gustatory disorders. In Smell and Taste in Health and Disease (T. V. Getchell, R. L. Doty, L. M. Bartoshuk, and J. B. Snow, Jr., Eds.), pp. 449-462. Raven Press, New York.
20. Dunnick, J. K., Elwell, M. R., Benson, J. M., Hobbs, C. H., Hahn, F. F., Haley, P. J., Cheng, Y. S., and Eidson, A. F. (1989). Lung toxicity after 13-week inhalation exposure to nickel oxide, nickel subsulfide, or nickel sulfate hexahydrate in F344/N rats and B6C3F, mice. Fundam. Appl. Toxicol 12, 584-594.
21. Farbman, A. I. (1990). Olfactory neurogenesis: Genetic or environmental controls? Trends Neurosci. 13, 362-365.
22. Ferriero, D., and Margolis, F. L. (1975). Denervation in the primary olfactory pathway of mice. II. Effects on carnosine and other amine compounds. Brain Res. 94, 75-86.
23. Friberg, L. (1948). Proteinurea and emphysema among workers exposed to cadmium and nickel dust in a storage battery plant. Proc. Int. Congr. I fid. Med 9, 641-644.
24. Furst, A., and Radding, S. B. (1984). New developments in the study of metal carcinogenesis. J. Environ. Sci. Health C2, 103-133.
25. Goyer, R. A. (1986). Toxic effects of metals. In Casarett and Doull’s Toxicology: The Basic Science of Poisons (C. D. Klaassen, M. O. Amdur, and J. DouJJ, Eds.), pp. 623-680. MacMillan, New York.
26. Harding, J. H., Getchell, T. V., and Margolis, F. L. (1978). Denervation of the primary olfactory pathway in mice. V. Long-term effect of intranasal ZnS04 irrigation on behavior, biochemistry and morphology. Brain Res. 140, 271-285.
27. Hasan, M., and Ali, S. F. (1981). Effects of thallium, nickel, and cobalt administration on the lipid peroxidation in different regions of the rat brain. Toxicol. Appl. Pharmacol. 57, 8-13.
28. Hastings, L., Miller M., Minnema, D., Evans, J., and Radike, R. (1991). Effects of methyl bromide on the rat olfactory system. Chem. Senses 16, 43-55.
29. Horstman, S., Barkley, B., Larson, E., and Bingham, E. (1973). Aerosols of lead, nickel and cadmium: A method of generating soluble and insoluble compounds. Arch. Environ. Health 26, 75-77.
30. KJein-Szanto, A. J. P., Boysen, M., and Reith, A. (1987). Keratin and involucrin in preneoplastic lesions. Arch. Pathol. Lab Med 111, 1057-1061.
31. Lancet, D. (1986). Vertebrate olfactory reception. Annu. Rev. Neurosci. 9, 329-355.
32. Macmillan, N. A., andCreelman, C. D. (1991). Detection Theory: A User’s Guide. Cambridge Univ. Press, Cambridge.
33. Matulionis, D. H., Breipohl, W., and Bhatnagar, K. P. (1982). Degeneration and regeneration of olfactory epithelium in the mouse. Ann. Otol. Rhinol. Laryngol. Suppl. 89, 1-12.
34. Medinsky, M. A., Benson, J. M., and Hobbs, C. H. (1987). Lung clearance and disposition of “Ni in F344/N rats after intratracheal instillation of nickel sulfate solutions. Environ. Res. 3, 168-178.
35. Miller M. L., Andringa, A., Evans, J., and Hastings, L. (1995). Occurrence of microvillar cells in the regenerating olfactory epithelium of the rat after exposure to methyl bromide. Brain Res., in press.
36. Misra, M., Rodriguez, R. E., and Kasprzak, K. S. (1990). Nickel induced lipid peroxidation in the rat: Correlation with nickel effect on antioxidant defense systems. Toxicology 64, 1-17.
37. Morgan, K. T„ and Monticello, T. M. (1990). Airflow, gas deposition, and lesion distribution in the nasal passages. Environ. Health Perspecl 88, 209-218.
38. Nordlund, K. (1990). Biological effects of mercuric chloride, nickel sulfate and nickel chloride. Prog. Med. Chem 27, 189-233.
39. Rodriguez, R. E., Misra, M., and Kasprzak, K. S. (1990). Effects of nickel on catalase activity in vitro and in vivo. Toxicology 63, 45-52.
40. Rodriguez, R. E., Misra, M., North, S. L., and Kasprzak, K. S. (1991). Nickel-induced lipid peroxidation in the liver of different strains of mice and its relation to nickel effects on antioxidant systems. Toxicol. Lett. 57, 269-281.
41. Rowley, J. C, Moran, D. T., and Jafek, B. W. (1989). Peroxidase backfills suggest the mammalian olfactory epithelium contains a second morphologically distinct class of bipolar sensory neuron: The microvillar cell. Brain Res. 502, 387-400.
42. Russell, N. J. (1972). Epidermal ultrastructure during wound healing in chick embryo. Ph.D. thesis, University of Minnesota.
43. Schwartz-Levey, M., Chikaraishi, D. M., and Kauer, J. S. (1991). Characterization of potential precursor populations in the mouse olfactory epithelium using immunocytochemistry and autoradiography. J. Neurosci. 11, 3556-3564.
44. Shainkin-Kestenbaum, R., Caruso, C., and Berlyne, G. M. (1991). Effect of nickel on oxygen free radical metabolism. Biol Trace Elem. Res. 28, 213-221.
45. Slotnick, B. M., and Schoonover, F. W. (1984). Olfactory thresholds in unilaterally bulbectomized rats. Chem. Senses 9, 325-340.
46. Snapper, A. G., and Inglis, G. B. (1982). State notation of behavioral procedures. Behav. Res Met. Inst. 14, 329-342.
47. Sorokin, S. P. (1977). The respiratory system: Nasal cavity and sinuses. In Histology: Cell and Tissue Biology (L. Weiss and R. O. Greep, Eds.), pp. 765-772. McGraw-Hill, New York.
48. Sunderman, W. F., Jr. (1977). The metabolism and toxicology of nickel. In Clinical Chemistry and Chemical Toxicology of Metals (S. S. Brown, Ed.), pp. 231-259. Elsevier/North-Holland Biomedical Press, New York.
49. Sunderman, F. W. (1986). Metals ad lipid peroxidation. Acta Pharmacol. Toxicol. Copenhagen 59, 248-255.
50. Suzuki, Y., and Takeda, M. (1991). Basal cells in the mouse olfactory epithelium after axonotomy: Immunohistochemical and electron-microscopic studies. Cell Tissue Res. 266, 239-245.
51. Torreilles, J., and Guerin, M. C. (1990). Nickel (II) as a temporary catalyst for hydroxyl radical generation. FEBS Lea. 272, 58-60.
52. Torjussen, W., Solberg, L. A., and Hogetveit, A. C. (1979). Histopathologi-cal changes of the nasal mucosa in active and retired nickel workers. Br. J. Cancer 40, 568-580.
53. Ulrich, L., Sulcova, M., Spacek, L., Neumanova, E., and Vladar, M. (1991). Investigation of professional nickel exposure in nickel refinery workers. Sci. Total Environ. 101, 91-96.
54. Uriah, L. C., Talley, F. A., Mitsumori, K., Gupta, B. N., Bucher, J. R„ and Boorman, G. A. (1987). Ultrastructural changes in the nasal mucosa of Fischer 344 rats and B6C3F1 mice following an acute exposure to methyl isocyanate. Environ. Health Perspect. 72, 77-88.
55. Winer, B. J. (1971). Design and analysis of factorial experiments. In Statistical Principles in Experimental Design, pp. 309-430. McGraw-Hill, New York.
56. Wood, R. J. (1982). Stimulus properties of inhaled substances: An update. In Nervous System Toxicology (C. L. Mitchell, Ed.), pp. 199-212. Raven Press, New York.
57. Yamagishi, M., Nakamura, H., Nakano, Y., and Kuwano, R. (1992). Immunohistochemical study of the fourth cell type in the olfactory epithelium in Guinea pigs and in a patient. ORL 54, 85-90.
58. Young, J. (1981). Histopathological examination of the rat nasal cavity. Fundam. Appl. Toxicol. 1, 309-312.