Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+CDS+thymocytes

Nature

Volumn 374, Issue 6521, 1995, Pages 474-476

  Fischer, Klaus Dieter ^a,b   Zmuidzinas, Antanina ^c,e   Gardner, Sandra ^a,b   Barbacid, Mariano ^c   Guidos, Cynthia ^b,d  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c BRISTOL MYERS SQUIBB   (United States)

^d HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^e EPG Research Foundation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CYTOPLASM PROTEIN; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; BLASTOCYST; CELL LINEAGE; CELL MATURATION; CONTROLLED STUDY; EMBRYO CELL; GENETIC COMPLEMENTATION; IMMUNOPHENOTYPING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTO ONCOGENE; SIGNAL TRANSDUCTION; STEM CELL; T LYMPHOCYTE; THYMOCYTE;

ANIMAL; ANTIGENS, CD4; ANTIGENS, CD8; B-LYMPHOCYTE SUBSETS; BONE MARROW CELLS; CELL DIFFERENTIATION; CELL LINE; CHIMERA; MICE; PROTEINS; PROTO-ONCOGENE PROTEINS; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; SUPPORT, NON-U.S. GOV'T; T-LYMPHOCYTE SUBSETS; THYMUS GLAND;

EID: 0028904413     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/374474a0     Document Type: Article

References (30)

1. von Boehmer, H. Cell 76, 219-228 (1994).
2. Nossal, G. J. V. Cell 76, 229-239 (1994).
3. Bustelo, X. R., Ledbetter, J. A. & Barbacid, M. Nature 356, 68-71 (1992).
4. Margolis, B. et al. Nature 356, 71-74 (1992).
5. Bustelo, X. R. & Barbacid, M. Science 256, 1196-1199 (1992).
6. Katzav, S., Martin-Zanca, D. & Barbacid, M. EMBO J. 8, 2283-2290 (1989).
7. Adams, J. M., Houston, H., Allen, J., Lints, T. & Harvey, R. Oncogene 7, 611-618 (1992).
8. Chen, J., Lansford, R., Stewart, V., Young, F. & Alt, F. W. Proc. natn. Acad. Sei. U.S.A. 90, 4528-4532 (1993).
9. Zmuidzlnas, A. et al. EMBO J. 14, 1-11 (1995).
10. Dosil, M„ Wang, S. & Lemischka, I. R. Molec. cell. Biol. 13, 6572-6585 (1993).
11. Godfrey, D„ Zlotnik, A. & Suda, T. J. Immun. 149, 2281-2285 (1992).
12. Rolink, A., Streb, M., Nishikawa, S.-I. & Melchers, F. Eur.J. Immun. 21, 2609-2612 (1991).
13. Robey, E. & Fowlkes, B. J. A. Rev. Immun. 12, 675-705 (1994).
14. Guidos, C. J., Danska, J. S., Fathman, C. G. & Weissman, I. L. J. exp. Med. 172, 835-845 (1990).
15. Davis, C. B., Killeen, N., Crooks, M. E. C., Raulet, D. & Littman, D. R. Cell 73, 237-247 (1993).
16. Chan, S. H., Cosgrove, D., Waltzinger, C., Benoist, C. & Mathis, D. Cell 73, 225-236 (1993).
17. van Meerwijk, J. P. M. & Germain, R. N. Science 261, 911-915 (1993).
18. Guidos, C. J. & Weissman, I. L. in Molecular Mechanisms of Immunological Self-recognition (eds Alt, F. & Vogel, H. j.) 137-147 (Academic, San Diego, 1993).
19. Bendelac, A., Matzinger, P., Seder, R. A., Paul, W. E. & Schwartz, R. H. J. exp. Med 175, 731-742 (1992).
20. Ashton-Rickardt, P. G. & Tonegawa, S. Immun. Today 15, 362-365 (1994).
21. Weiss, A. & Littman, D. R. Cell 76, 263-274 (1994).
22. Gulbins, E. et al. Science 260, 822-824 (1993).
23. Boguski, M. S. & McCormick, F. Nature 366, 643-654 (1993).
24. Molina, T. J. et al. Nature 357, 161-164 (1992).
25. Mombaerts, P., Anderson, S. J., Perlmutter, R. M., Mak, T. W. & Tonegawa, S. Immunity 1, 261-267 (1994).
26. Arpaia, E., Shahar, M., Dadi, H., Cohen, A. & Roifman, C. Cell 76, 947-958 (1994).
27. Chan, A. et al. Science 264, 1599-1601 (1994)
28. Elder, M. et al. Science 264, 1596-1599 (1994).
29. Kishihara, K. et al. Cell 74, 143-156 (1993).
30. Danska, J. S. et al. Science 266, 450-455 (1994).