Expression of vascular endothelial growt factor and its receptors fit and KDR in ovarian carcinoma

Journal of the National Cancer Institute

Volumn 87, Issue 7, 1995, Pages 506-516

  Boocock, Christine A ^a   Charnock jones, D Stephen ^a   Sharkey, Andrew M ^a   Mclaren, John ^a   Barker, Patrick J ^b   Wright, Karen A ^c   Twentyman, Peter R ^c   Smith, Stephen K ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b BABRAHAM INSTITUTE   (United Kingdom)

^c MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH FACTOR RECEPTOR; VASCULOTROPIN;

ARTICLE; ASCITES; CANCER MORTALITY; HUMAN; HUMAN CELL; HUMAN TISSUE; LIGAND BINDING; OVARY CARCINOMA; RECEPTOR BINDING; VASCULAR ENDOTHELIUM;

BASE SEQUENCE; CARCINOMA; ENDOTHELIAL GROWTH FACTORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LYMPHOKINES; MOLECULAR SEQUENCE DATA; OVARIAN NEOPLASMS; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, GROWTH FACTOR; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR; RNA, MESSENGER; RNA, NEOPLASM; SUPPORT, NON-U.S. GOV'T; TUMOR CELLS, CULTURED; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1;

EID: 0028904030     PISSN: 00278874     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnci/87.7.506     Document Type: Article

References (46)

1. Young RC, Decker DG, Wharton JT, et al: Staging laparotomy in early ovarian cancer. JAMA 250:3072-3076, 1983.
2. Plaxe SC, Deligdisch L, Dottino PR, el air Ovarian intraepithelial neoplasia demonstrated in patients with stage I ovarian carcinoma. Gynecol Oncol 38:367-372, 1990.
3. Fearon ER, Vogelstein B: A genetic model for colorectal tumorigertesis. Cell 61:759-767, 1990.
4. Kacinski BM, Carter D, Mittal K, et al: Ovarian adenocarcinomas express fms-complementary transcripts and fms antigen, often with coexpression of CSF-1. Am J Pathol 137:135-147, 1990.
5. Wu S, Boyer CM, Whitaker RS, et al: Tumor necrosis factor alpha as autocrine and paracrine growth factor for ovarian cancer: monokine induction of tumor cell proliferation and tumor necrosis factor alpha expression. Cancer Res 53:1939-1944, 1993.
6. Folkman J, Klagsbrun M: Angiogenic factors. Science 235:442-447, 1987.
7. Senger DR, Galli SJ, Dvorak AM, et al. Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 219:983-985,1983.
8. Senger DR, Perruzzi CA, Feder J. et al: A highly conserved vascular permeability factor secreted by a variety of human and rodent tumor cell lines. Cancer Res 46:5629-5632, 1986.
9. Ferrara N, Henzel WJ: Pituitary follicular cells secrete a novel heparinbinding growth factor specific for vascular endothelial cells. Biochem Biophys Res Commun 161:851-858, 1989.
10. Connolly DT, Heuvelman DM, Nelson R, et al: Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis. J Clin Invest 84:1470-1478, 1989.
11. Houck KA, Ferrara N, Winer J, et al: The vascular endothelial growth factor family: identification of a fourth molecular species and characterization of alternative splicing of RNA. Mol Endocrinol 5: 1806-1814, 1991.
12. Houck KA, Leung DW, Rowland AM, et al: Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms. J Biol Chem 267:26031-26037,1992.
13. Chamock-Jones DS, Sharkey AM, Rajput-Williams J, et al: Identification and localization of alternately spliced mRNAs for vascular endothelial growth factor in human uterus and estrogen regulation in endometrial carcinoma cell lines. Biol Reprod 48:1120-1128, 1993.
14. Ravindranath N, Little-lhrig L, Phillips HS, et al: Vascular endothelial growth factor messenger ribonucleic acid expression in the primate ovary. Endocrinology 131:254-260, 1992.
15. Olson TA, Mohanraj D, Carson LF, et al: Vascular permeability factor gene expression in normal and neoplastic human ovaries. Cancer Res 54:276-280, 1994.
16. Gitay-Goren H, Halaban R, Neufeld G: Human melanoma cells but not normal melanocytes express vascular endothelial growth factor receptors. Biochem Biophys Res Commun 190:702-708, 1993.
17. Berse B, Brown LF, Van De Water L, et al: Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages, and tumors. Mol Biol Cell 3:211-220, 1992.
18. Brown LF, Berse B, Jackman RW, et al: Increased expression of vascular permeabiity factor (vascular endothelial growth factor) and its receptors in kidney and bladder carcinomas. Am J Pathol 143:1255-1262, 1993.
19. Berkman RA, Merrill MJ, Reinhold WC, et al: Expression of the vascular permeability factor/vascular endothelial growth factor gene in central nervous system neoplasms. J Clin Invest 91:153-159, 1993.
20. de Vries C, Escobedo JA, Ueno H, et al: The fms-like tyrosine kinase, a ’ receptor for vascular endothelial growth factor. Science 255:989-991, 1992.
21. Terman BI, Dougher-Vermazen M, Carrion ME, et al: Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor. Biochem Biophys Res Commun 187:1579-1586, 1992.
22. Jakeman LB, Winer J, Bennett GL, et al: Binding sites for vascular endothelial growth factor are localized on endothelial cells in adult rat tissues. J Clin Invest 89:244-253, 1992.
23. Shen H, Clauss M, Ryan J, et al: Characterization of vascular permeability factor/vascular endothelial growth factor receptors on mononuclear phagocytes. Blood 81:2767-2773, 1993.
24. Shibuya M, Yamaguchi S, Yamane A, et al: Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (fit) closely related to the fms family. Oncogene 5:519-524, 1990.
25. Chamock-Jones DS, Sharkey AM, Boocock CA, et al: Vascular endothelial growth factor receptor localization and activation in human trophoblast and choriocarcinoma cells. Biol Reprod 51:524-530, 1994.
26. Pepper MS, Ferrara N, Orci L, et al: Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells. Biochem Biophys Res Commun 181:902-906, 1991.
27. Unemori EN, Ferrara N, Bauer EA, et al: Vascular endothelial growth factor induces interstitial collagenase expression in human endothelial cells. J Cell Physiol 153:557-562, 1992.
28. +and von Willebrand factor release in human endothelial cells. Am J Pathol 138:213-221, 1991.
29. Cordell JL, Falini B, Erber WN, et al: Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes). J His-tochem Cytochem 32:219-229, 1984.
30. Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidinum thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159,1987.
31. Kendall RL, Thomas KA: Inhibition of vascular endothelial growth factor activity by an endogenously encoded soluble receptor. Proc Natl Acad Sci US A 90:10705-10709, 1993.
32. Lewin B: The apparatus for nuclear splicing. In Genes 5. Oxford: Oxford University Press, 1994, pp 913-914.
33. Plate KH, Breier G, Weich HA, et al: Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature 359:845-848,1992.’.
34. Brown LF, Berse B, Jackman RW, et al: Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in adenocarcinomas of the gastrointestinal tract. Cancer Res 53:4727-4735, 1993.
35. Gamdo C, Saule S, Gospodarowicz D: Transcriptional regulation of vascular endothelial growth factor gene expression in ovarian bovine granulosa cells. Growth Factors 8:109-117, 1993.
36. Finkenzeller G, Marme D, Weich HA, et al: Platelet-derived growth factor-induced transcription of the vascular endothelial growth factor gene is mediated by protein kinase C. Cancer Res 52:4821-4823, 1992.
37. Goldman CK, Kim J, Wong WL, et al: Epidermal growth factor stimulates endothelial growth factor production by human malignant glioma cells: a model of glioblastoma multiforme pathophysiology. Mol Biol Cell 4:121-133,1993.
38. Schweiki D, Itin A, Soffer D, et al: Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 359:843-845,1992.
39. Breier G, Albrecht U, Sterrer S, et al: Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation. Development 114:521-532,1992.
40. Nagy JA, Brown LF, Senger DR, et al: Pathogenesis of tumor stroma generation: a critical role for leaky blood vessels and fibrin deposition. Biochim Biophys Acta 948:305-326, 1988.
41. Dvorak HF, Nagy JA, Berse B, et al: Vascular permeability factor, fibrin, and the pathogenesis of tumor stroma formation. Ann N Y Acad Sci 667:101-111,1991.
42. Ferrara N, Winer J, Burton T, et al: Expression of vascular endothelial growth factor does not promote transformation but confers a growth advantage in vivo to Chinese hamster ovary cells. J Clin Invest 91:160-170, 1993.
43. Kim KJ, Li B, Winer J, et al: Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature 362:841-844,1993.
44. Millauer B, Shawver LK, Plate KH, et al: Glioblastoma growth inhibited in vivo by a dominant negative Flk-1 mutant. Nature 367:576-579,1994.
45. Kim KJ, Houck K, Winer J, et al: The vascular endothelial growth factor proteins: identification of biologically relevant regions by neutralizing monoclonal antibodies. Growth Factors 7:53-64, 1992.
46. Millauer B, Wizigmann-Voos S, Schnurch H, et al: High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis. Cell 72:835-846, 1993.