-
1
-
-
0017688347
-
In a radiation chimaera, host H-2 antigens determine immune responsiveness of donor cytotoxic cells
-
Bevan MJ. 1977. In a radiation chimaera, host H-2 antigens determine immune responsiveness of donor cytotoxic cells. Nature 269:417-18
-
(1977)
Nature
, vol.269
, pp. 417-418
-
-
Bevan, M.J.1
-
2
-
-
0018085532
-
On the thymus in the differentiation of "H-2 self-recognition" by T cells: Evidence for dual recognition?
-
Zinkernagel RM, Callahan GN, Althage A, Cooper S, Klein PA, Klein J. 1978. On the thymus in the differentiation of "H-2 self-recognition" by T cells: evidence for dual recognition? J. Exp. Med. 147:882-96
-
(1978)
J. Exp. Med.
, vol.147
, pp. 882-896
-
-
Zinkernagel, R.M.1
Callahan, G.N.2
Althage, A.3
Cooper, S.4
Klein, P.A.5
Klein, J.6
-
3
-
-
0018126188
-
H-2 antigens of the thymus determine lymphocyte specificity
-
Fink PJ, Bevan MJ. 1978. H-2 antigens of the thymus determine lymphocyte specificity. J. Exp. Med. 148:766-75
-
(1978)
J. Exp. Med.
, vol.148
, pp. 766-775
-
-
Fink, P.J.1
Bevan, M.J.2
-
4
-
-
0023522053
-
Function and specificity of T cell subsets in the mouse
-
Sprent J, Webb SR. 1987. Function and specificity of T cell subsets in the mouse. Adv. Immunol. 41:39-133
-
(1987)
Adv. Immunol.
, vol.41
, pp. 39-133
-
-
Sprent, J.1
Webb, S.R.2
-
5
-
-
0025231503
-
Developmental biology of T cells in T cell-receptor transgenic mice
-
von Boehmer H. 1990. Developmental biology of T cells in T cell-receptor transgenic mice. Annu. Rev. Immunol. 8:531-56
-
(1990)
Annu. Rev. Immunol.
, vol.8
, pp. 531-556
-
-
Von Boehmer, H.1
-
9
-
-
0026091380
-
Mice lacking MHC class II molecules
-
Cosgrove D, Gray D, Dierich A, Kaufman J, Lemeur M, Benoist C, Mathis D. 1991. Mice lacking MHC class II molecules. Cell 66:1051-66
-
(1991)
Cell
, vol.66
, pp. 1051-1066
-
-
Cosgrove, D.1
Gray, D.2
Dierich, A.3
Kaufman, J.4
Lemeur, M.5
Benoist, C.6
Mathis, D.7
-
11
-
-
0023475192
-
The T cell receptor
-
Marrack P, Kappler J. 1987. The T cell receptor. Science 238:1073-79
-
(1987)
Science
, vol.238
, pp. 1073-1079
-
-
Marrack, P.1
Kappler, J.2
-
12
-
-
0027448853
-
Comparison of peptides bound to spleen and thymus class II
-
Marrack P, Ignatowicz L, Kappler JW, Boymel J, Freed JH. 1993. Comparison of peptides bound to spleen and thymus class II. J. Exp. Med. 178:2173-8364
-
(1993)
J. Exp. Med.
, vol.178
, pp. 2173-8364
-
-
Marrack, P.1
Ignatowicz, L.2
Kappler, J.W.3
Boymel, J.4
Freed, J.H.5
-
13
-
-
0027450835
-
Thymus epithelium induces tissue-specific tolerance
-
Bonomo A, Matzinger P. 1993. Thymus epithelium induces tissue-specific tolerance. J. Exp. Med. 177:1153-64
-
(1993)
J. Exp. Med.
, vol.177
, pp. 1153-1164
-
-
Bonomo, A.1
Matzinger, P.2
-
14
-
-
0026587483
-
Clonal deletion induced by either radioresistant thymic host cells or lymphohemopoietic donor cells at different stages of class I-restricted T cell ontogeny
-
Speiser DE, Pircher H, Ohashi PS, Kyburz D, Hengartner H, Zinkernagel RM. 1992. Clonal deletion induced by either radioresistant thymic host cells or lymphohemopoietic donor cells at different stages of class I-restricted T cell ontogeny. J. Exp. Med. 175:1277-83
-
(1992)
J. Exp. Med.
, vol.175
, pp. 1277-1283
-
-
Speiser, D.E.1
Pircher, H.2
Ohashi, P.S.3
Kyburz, D.4
Hengartner, H.5
Zinkernagel, R.M.6
-
15
-
-
0026688409
-
Inefficient positive selection of T cells directed by haematopoietic cells
-
Bix M, Raulet D. 1992. Inefficient positive selection of T cells directed by haematopoietic cells. Nature 359:330-33
-
(1992)
Nature
, vol.359
, pp. 330-333
-
-
Bix, M.1
Raulet, D.2
-
16
-
-
0026788098
-
Positive selection of T-lymphocytes induced by intrathymic injection of a thymic epithelial cell line
-
Vukmanović S, Grandea AG III, Faas SJ, Knowles BB, Bevan MJ. 1 992. Positive selection of T-lymphocytes induced by intrathymic injection of a thymic epithelial cell line. Nature 359:729-32
-
(1992)
Nature
, vol.359
, pp. 729-732
-
-
Vukmanović, S.1
Grandea III, A.G.2
Faas, S.J.3
Knowles, B.B.4
Bevan, M.J.5
-
17
-
-
0026727222
-
A cell line that can induce thymocyte positive selection
-
Hugo P, Kappler JW, Godfrey DI, Marrack PC. 1992. A cell line that can induce thymocyte positive selection. Nature 360:679-82
-
(1992)
Nature
, vol.360
, pp. 679-682
-
-
Hugo, P.1
Kappler, J.W.2
Godfrey, D.I.3
Marrack, P.C.4
-
20
-
-
0022885485
-
Induction of MHC-restricted specificity and tolerance in the thymus
-
Lo D, Ron Y, Sprent J. 1986. Induction of MHC-restricted specificity and tolerance in the thymus. Immunol. Res. 5:221-32
-
(1986)
Immunol. Res.
, vol.5
, pp. 221-232
-
-
Lo, D.1
Ron, Y.2
Sprent, J.3
-
21
-
-
0025743727
-
A unified model for T cell antigen recognition and thymic selection of the T cell repertoire
-
Mannie MD. 1991. A unified model for T cell antigen recognition and thymic selection of the T cell repertoire. J. Theor. Biol. 151:169-92
-
(1991)
J. Theor. Biol.
, vol.151
, pp. 169-192
-
-
Mannie, M.D.1
-
22
-
-
0024950897
-
Cross-linking and conformational change in T-cell receptors: Role in activation and in repertoire selection
-
Janeway CA Jr. Dianzani U, Portoles P, Rath S, Reich EP, Rojo J, Yagi J, Murphy DB. 1989. Cross-linking and conformational change in T-cell receptors: role in activation and in repertoire selection. Cold. Spring. Harb. Symp. Quant. Biol. 54(2):657-66
-
(1989)
Cold. Spring. Harb. Symp. Quant. Biol.
, vol.54
, Issue.2
, pp. 657-666
-
-
Janeway Jr., C.A.1
Dianzani, U.2
Portoles, P.3
Rath, S.4
Reich, E.P.5
Rojo, J.6
Yagi, J.7
Murphy, D.B.8
-
23
-
-
0006723284
-
High fives or hand clasps?
-
Janeway CA. 1993. High fives or hand clasps? Curr. Biol. 2:591-93
-
(1993)
Curr. Biol.
, vol.2
, pp. 591-593
-
-
Janeway, C.A.1
-
24
-
-
0027333348
-
Tickling the TCR: Selective T-cell functions stimulated by altered peptide ligands
-
Evavold BD, Sloan-Lancaster J, Allen PM. 1993. Tickling the TCR: selective T-cell functions stimulated by altered peptide ligands. Immunol. Today 14:602-9
-
(1993)
Immunol. Today
, vol.14
, pp. 602-609
-
-
Evavold, B.D.1
Sloan-Lancaster, J.2
Allen, P.M.3
-
25
-
-
0028345391
-
Antigen analogs/MHC complexes as specific T cell receptor antagonists
-
Sette A, Alexander J, Ruppert J, Snoke K, Franco A, Ishioka G, Grey HM. 1994. Antigen analogs/MHC complexes as specific T cell receptor antagonists. Annu. Rev. Immunol. 12:413-32
-
(1994)
Annu. Rev. Immunol.
, vol.12
, pp. 413-432
-
-
Sette, A.1
Alexander, J.2
Ruppert, J.3
Snoke, K.4
Franco, A.5
Ishioka, G.6
Grey, H.M.7
-
27
-
-
0028201339
-
Selective events in T cell development
-
Robey E, Fowlkes BJ. 1994. Selective events in T cell development. Annu. Rev. Immunol. 12:675-705
-
(1994)
Annu. Rev. Immunol.
, vol.12
, pp. 675-705
-
-
Robey, E.1
Fowlkes, B.J.2
-
28
-
-
0024566240
-
Molecular and cellular events of T cell development
-
Fowlkes BJ, Pardoll DM. 1989. Molecular and cellular events of T cell development. Adv. Immunol. 44:207-64
-
(1989)
Adv. Immunol.
, vol.44
, pp. 207-264
-
-
Fowlkes, B.J.1
Pardoll, D.M.2
-
29
-
-
0025035509
-
T cell receptor-mediated negative selection of autoreactive T lymphocyte precursors occurs after commitment to the CD4 or CD8 lineages
-
Guidos CJ, Danska JS, Fathman CG, Weissman IL. 1990. T cell receptor-mediated negative selection of autoreactive T lymphocyte precursors occurs after commitment to the CD4 or CD8 lineages. J. Exp. Med. 172:835-45
-
(1990)
J. Exp. Med.
, vol.172
, pp. 835-845
-
-
Guidos, C.J.1
Danska, J.S.2
Fathman, C.G.3
Weissman, I.L.4
-
30
-
-
0028354215
-
Small cortical thymocytes are subject to positive selection
-
Lundberg K, Shortman K. 1994. Small cortical thymocytes are subject to positive selection. J. Exp. Med. 179:1475-83
-
(1994)
J. Exp. Med.
, vol.179
, pp. 1475-1483
-
-
Lundberg, K.1
Shortman, K.2
-
33
-
-
0025607947
-
Lineage relationships and developmental kinetics of immature thymocytes: CD3 CD4, and CD8 acquisition in vivo and in vitro
-
Petrie HT, Hugo P, Scollay R, Shortman K. 1990. Lineage relationships and developmental kinetics of immature thymocytes: CD3 CD4, and CD8 acquisition in vivo and in vitro. J. Exp. Med. 172:1583-88
-
(1990)
J. Exp. Med.
, vol.172
, pp. 1583-1588
-
-
Petrie, H.T.1
Hugo, P.2
Scollay, R.3
Shortman, K.4
-
34
-
-
0025337709
-
Positive selection is an early event in thymocyte differentiation: High TCR expression by cycling immature thymocytes precedes final maturation by several days
-
Penit C. 1990. Positive selection is an early event in thymocyte differentiation: high TCR expression by cycling immature thymocytes precedes final maturation by several days. Int. Immunol. 2:629-38
-
(1990)
Int. Immunol.
, vol.2
, pp. 629-638
-
-
Penit, C.1
-
35
-
-
0026030196
-
+) thymocytes as post-selection intermediates leading to mature T cells
-
+) thymocytes as post-selection intermediates leading to mature T cells, J. Exp. Med. 173:323-32
-
(1991)
J. Exp. Med.
, vol.173
, pp. 323-332
-
-
Shortman, K.1
Vremec, D.2
Egerton, M.3
-
36
-
-
0025184378
-
Distinct sequence of negative or positive selection implied by thymocyte T-cell receptor densities
-
Ohashi PS, Pircher H, Burki K, Zinkernagel RM, Hengartner H. 1990. Distinct sequence of negative or positive selection implied by thymocyte T-cell receptor densities. Nature 346:861-63
-
(1990)
Nature
, vol.346
, pp. 861-863
-
-
Ohashi, P.S.1
Pircher, H.2
Burki, K.3
Zinkernagel, R.M.4
Hengartner, H.5
-
37
-
-
0026078307
-
Development of the CD4 and CD8 lineage of T cells: Instruction versus selection
-
Borgulya P, Kishi H, Muller U, Kirberg J. von Boehmer H. 1991. Development of the CD4 and CD8 lineage of T cells: instruction versus selection. EMBO J. 10:913-18
-
(1991)
EMBO J.
, vol.10
, pp. 913-918
-
-
Borgulya, P.1
Kishi, H.2
Muller, U.3
Von Boehmer H, K.J.4
-
39
-
-
0028229558
-
Production, selection, and maturation of thymocytes with high surface density of TCR
-
Lucas B, Vasseur F, Penit C. 1994. Production, selection, and maturation of thymocytes with high surface density of TCR. J. Immunol. 153:53-62
-
(1994)
J. Immunol.
, vol.153
, pp. 53-62
-
-
Lucas, B.1
Vasseur, F.2
Penit, C.3
-
40
-
-
0024450056
-
Positive selection of the T cell repertoire: Where and when does it occur?
-
Benoist C, Mathis D. 1989. Positive selection of the T cell repertoire: where and when does it occur? Cell 58:1027-33
-
(1989)
Cell
, vol.58
, pp. 1027-1033
-
-
Benoist, C.1
Mathis, D.2
-
42
-
-
0025933951
-
Kinetics and efficacy of positive selection in the thymus of normal and T cell receptor transgenic mice
-
Huesmann M, Scott B, Kisielow P, von Boehmer H. 1991. Kinetics and efficacy of positive selection in the thymus of normal and T cell receptor transgenic mice. Cell 66:533-40
-
(1991)
Cell
, vol.66
, pp. 533-540
-
-
Huesmann, M.1
Scott, B.2
Kisielow, P.3
Von Boehmer, H.4
-
43
-
-
0024381358
-
A nondeletional mechanism of thymic self tolerance
-
Ramsdell F, Lantz T, Fowlkes BJ. 1989. A nondeletional mechanism of thymic self tolerance. Science 246:1038-41
-
(1989)
Science
, vol.246
, pp. 1038-1041
-
-
Ramsdell, F.1
Lantz, T.2
Fowlkes, B.J.3
-
44
-
-
0026721377
-
Exclusion and inclusion of alpha and beta T cell receptor alleles
-
Borgulya P, Kishi H, Uematsu Y, von Boehmer H. 1992. Exclusion and inclusion of alpha and beta T cell receptor alleles. Cell 69:529-37
-
(1992)
Cell
, vol.69
, pp. 529-537
-
-
Borgulya, P.1
Kishi, H.2
Uematsu, Y.3
Von Boehmer, H.4
-
45
-
-
0027220211
-
Multiple rearrangements in T cell receptor alpha chain genes maximize the production of useful thymocytes
-
Petrie HT, Livak F, Schatz DG, Strasser A, Crispe IN, Shortman K. 1993. Multiple rearrangements in T cell receptor alpha chain genes maximize the production of useful thymocytes. J. Exp. Med. 178:615-22
-
(1993)
J. Exp. Med.
, vol.178
, pp. 615-622
-
-
Petrie, H.T.1
Livak, F.2
Schatz, D.G.3
Strasser, A.4
Crispe, I.N.5
Shortman, K.6
-
47
-
-
0027130238
-
Bcl-2/Bax: A rheostat that regulates an anti-oxidant pathway and cell death
-
Korsmeyer SJ, Shutter JR, Veis DJ, Merry DE, Oltvai ZN. 1993. Bcl-2/Bax: a rheostat that regulates an anti-oxidant pathway and cell death. Semin. Cancer Biol. 4:327-32
-
(1993)
Semin. Cancer Biol.
, vol.4
, pp. 327-332
-
-
Korsmeyer, S.J.1
Shutter, J.R.2
Veis, D.J.3
Merry, D.E.4
Oltvai, Z.N.5
-
48
-
-
0025751550
-
Bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes
-
Sentman CL, Shutter JR, Hockenbery D, Kanagawa O, Korsmeyer SJ. 1991. bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes. Cell 67:879-88
-
(1991)
Cell
, vol.67
, pp. 879-888
-
-
Sentman, C.L.1
Shutter, J.R.2
Hockenbery, D.3
Kanagawa, O.4
Korsmeyer, S.J.5
-
49
-
-
0025786164
-
Bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship
-
Strasser A, Harris AW, Cory S. 1991. bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship. Cell 67:889-99
-
(1991)
Cell
, vol.67
, pp. 889-899
-
-
Strasser, A.1
Harris, A.W.2
Cory, S.3
-
52
-
-
0028117306
-
Positive and negative selection of T cells in T-cell receptor transgenic mice expressing a bcl-2 transgene
-
Strasser A, Harris AW, von Boehmer H, Cory S. 1994. Positive and negative selection of T cells in T-cell receptor transgenic mice expressing a bcl-2 transgene. Proc. Natl. Acad. Sci. USA 91:1376-80
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 1376-1380
-
-
Strasser, A.1
Harris, A.W.2
Von Boehmer, H.3
Cory, S.4
-
53
-
-
0027427492
-
Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair
-
Veis DJ, Sorenson CM, Shutter JR, Korsmeyer SJ. 1993. Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair. Cell 75:229-40
-
(1993)
Cell
, vol.75
, pp. 229-240
-
-
Veis, D.J.1
Sorenson, C.M.2
Shutter, J.R.3
Korsmeyer, S.J.4
-
54
-
-
0027527099
-
Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric mice
-
Nakayama K, Negishi I, Kuida K, Shinkai Y, Louie MC, Fields LE, Lucas PJ, Stewart V, Alt FW, Loh DY. 1993. Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric mice. Science 261:1584-88
-
(1993)
Science
, vol.261
, pp. 1584-1588
-
-
Nakayama, K.1
Negishi, I.2
Kuida, K.3
Shinkai, Y.4
Louie, M.C.5
Fields, L.E.6
Lucas, P.J.7
Stewart, V.8
Alt, F.W.9
Loh, D.Y.10
-
55
-
-
0027282044
-
Bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
-
Boise LH, González García M, Postema CE, Ding L, Lindsten T, Turka LA, Mao X, Nunez G, Thompson CB. 1993. bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell 74:597-608
-
(1993)
Cell
, vol.74
, pp. 597-608
-
-
Boise, L.H.1
González García, M.2
Postema, C.E.3
Ding, L.4
Lindsten, T.5
Turka, L.A.6
Mao, X.7
Nunez, G.8
Thompson, C.B.9
-
56
-
-
0027166048
-
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
-
Oltvai ZN, Milliman CL, Korsmeyer SJ. 1993. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74:609-19
-
(1993)
Cell
, vol.74
, pp. 609-619
-
-
Oltvai, Z.N.1
Milliman, C.L.2
Korsmeyer, S.J.3
-
57
-
-
0026553435
-
Activation events during thymic selection
-
Bendelac A, Matzinger P, Seder RA, Paul WE, Schwartz RH. 1992. Activation events during thymic selection. J. Exp. Med. 175:731-42
-
(1992)
J. Exp. Med.
, vol.175
, pp. 731-742
-
-
Bendelac, A.1
Matzinger, P.2
Seder, R.A.3
Paul, W.E.4
Schwartz, R.H.5
-
59
-
-
0027427713
-
CD69 cell surface expression identifies developing thymocytes which audition for T cell antigen receptor-mediated positive selection
-
Yamashita I, Nagata T, Tada T, Nakayama T. 1993. CD69 cell surface expression identifies developing thymocytes which audition for T cell antigen receptor-mediated positive selection. Int. Immunol. 5:1139-50
-
(1993)
Int. Immunol.
, vol.5
, pp. 1139-1150
-
-
Yamashita, I.1
Nagata, T.2
Tada, T.3
Nakayama, T.4
-
60
-
-
0025785134
-
Thymocyte expression of RAG-1 and RAG-2: Termination by T cell receptor cross-linking
-
Turka LA, Schatz DG, Oettinger MA, Chun JJ, Gorka C, Lee K, McCormack WT, Thompson CB. 1991. Thymocyte expression of RAG-1 and RAG-2: termination by T cell receptor cross-linking. Science 253:778-81
-
(1991)
Science
, vol.253
, pp. 778-781
-
-
Turka, L.A.1
Schatz, D.G.2
Oettinger, M.A.3
Chun, J.J.4
Gorka, C.5
Lee, K.6
McCormack, W.T.7
Thompson, C.B.8
-
61
-
-
0026661878
-
Engagement of the T-cell receptor during positive selection in the thymus down-regulates RAG-1 expression
-
Brandie D, Muller C, Rulicke T, Hengartner H, Pircher H. 1992. Engagement of the T-cell receptor during positive selection in the thymus down-regulates RAG-1 expression. Proc. Natl. Acad. Sci. USA 89:9529-33
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 9529-9533
-
-
Brandie, D.1
Muller, C.2
Rulicke, T.3
Hengartner, H.4
Pircher, H.5
-
62
-
-
0027153897
-
Another view of the selective model of thymocyte selection
-
Chan SH, Cosgrove D, Waltzinger C, Benoist C, Mathis D. 1993. Another view of the selective model of thymocyte selection. Cell 73:225-36
-
(1993)
Cell
, vol.73
, pp. 225-236
-
-
Chan, S.H.1
Cosgrove, D.2
Waltzinger, C.3
Benoist, C.4
Mathis, D.5
-
63
-
-
0027266755
-
Evidence for a stochastic mechanism in the differentiation of mature subsets of T lymphocytes
-
Davis CB, Killeen N, Crooks ME, Raulet D, Littman DR. 1993. Evidence for a stochastic mechanism in the differentiation of mature subsets of T lymphocytes. Cell 73:237-47
-
(1993)
Cell
, vol.73
, pp. 237-247
-
-
Davis, C.B.1
Killeen, N.2
Crooks, M.E.3
Raulet, D.4
Littman, D.R.5
-
64
-
-
0027164960
-
+ thymocytes: Selection rather than instruction?
-
+ thymocytes: selection rather than instruction? Science 261:911-15
-
(1993)
Science
, vol.261
, pp. 911-915
-
-
Van Meerwijk, J.P.1
Germain, R.N.2
-
65
-
-
0028053092
-
Stochastic component to development of class I major histocompatibility complex-specific T cells
-
Itano A, Kioussis D, Robey E. 1994. Stochastic component to development of class I major histocompatibility complex-specific T cells. Proc. Natl. Acad. Sci. USA 91:220-24
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 220-224
-
-
Itano, A.1
Kioussis, D.2
Robey, E.3
-
66
-
-
0028107416
-
Regulation of RAG-1 and CD69 expression in the thymus during positive and negative selection
-
Brandie D, Muller S, Muller C, Hengartner H, Pircher H. 1994. Regulation of RAG-1 and CD69 expression in the thymus during positive and negative selection. Eur. J. Immunol. 24:145-51
-
(1994)
Eur. J. Immunol.
, vol.24
, pp. 145-151
-
-
Brandie, D.1
Muller, S.2
Muller, C.3
Hengartner, H.4
Pircher, H.5
-
67
-
-
0025064213
-
Functional and phenotypic delineation of two subsets of CD4 single positive cells in the thymus
-
Nikolić Zugić J, Bevan MJ. 1990. Functional and phenotypic delineation of two subsets of CD4 single positive cells in the thymus. Int. Immunol. 2:135-41
-
(1990)
Int. Immunol.
, vol.2
, pp. 135-141
-
-
Nikolić Zugić, J.1
Bevan, M.J.2
-
69
-
-
0027328487
-
- thymocytes by class 1 molecules expressed by hematopoietic cells
-
- thymocytes by class 1 molecules expressed by hematopoietic cells. J. Exp. Med. 178:901-8
-
(1993)
J. Exp. Med.
, vol.178
, pp. 901-908
-
-
Bix, M.1
Coles, M.2
Raulet, D.3
-
71
-
-
0022597528
-
Identity of cells that imprint H-2-restricted T-cell specificity in the thymus
-
Lo D, Sprent J. 1986. Identity of cells that imprint H-2-restricted T-cell specificity in the thymus. Nature 319:672-75
-
(1986)
Nature
, vol.319
, pp. 672-675
-
-
Lo, D.1
Sprent, J.2
-
72
-
-
0024428184
-
Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand
-
Berg LJ, Pullen AM, Fazekas de St Groth B, Mathis D, Benoist C, Davis MM. 1989. Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand. Cell 58:1035-46
-
(1989)
Cell
, vol.58
, pp. 1035-1046
-
-
Berg, L.J.1
Pullen, A.M.2
Fazekas De St Groth, B.3
Mathis, D.4
Benoist, C.5
Davis, M.M.6
-
74
-
-
0027313656
-
T cell receptor targeting to thymic cortical epithelial cells in vivo induces survival, activation and differentiation of immature thymocytes
-
Müller KP, Kyewski BA. 1993. T cell receptor targeting to thymic cortical epithelial cells in vivo induces survival, activation and differentiation of immature thymocytes. Eur. J. Immunol. 23:1661-70
-
(1993)
Eur. J. Immunol.
, vol.23
, pp. 1661-1670
-
-
Kp, M.1
Kyewski, B.A.2
-
75
-
-
0026737664
-
Studies on T cell maturation on defined thymic stromal cell populations in vitro
-
Jenkinson EJ, Anderson G, Owen JJ. 1992. Studies on T cell maturation on defined thymic stromal cell populations in vitro. J. Exp. Med. 176:845-53
-
(1992)
J. Exp. Med.
, vol.176
, pp. 845-853
-
-
Jenkinson, E.J.1
Anderson, G.2
Owen, J.J.3
-
76
-
-
0027465451
-
MHC class II-positive epithelium and mesenchyme cells are both required for T-cell development in the thymus
-
Anderson G, Jenkinson EJ, Moore NC, Owen JJ. 1993. MHC class II-positive epithelium and mesenchyme cells are both required for T-cell development in the thymus. Nature 362:70-73
-
(1993)
Nature
, vol.362
, pp. 70-73
-
-
Anderson, G.1
Jenkinson, E.J.2
Moore, N.C.3
Owen, J.J.4
-
78
-
-
0026681679
-
The T cell receptor as a multicomponent signalling machine: CD4/CD8 coreceptors and CD45 in T cell activation
-
Janeway CA Jr. 1992. The T cell receptor as a multicomponent signalling machine: CD4/CD8 coreceptors and CD45 in T cell activation. Annu. Rev. Immunol. 10:645-74
-
(1992)
Annu. Rev. Immunol.
, vol.10
, pp. 645-674
-
-
Janeway Jr., C.A.1
-
80
-
-
0025817991
-
+ cells but markedly decreased helper cell activity in mice lacking CD4
-
+ cells but markedly decreased helper cell activity in mice lacking CD4. Nature 353:180-84
-
(1991)
Nature
, vol.353
, pp. 180-184
-
-
Rahemtulla, A.1
Fung Leung, W.P.2
Schilham, M.W.3
Kundig, T.M.4
Sambhara, S.R.5
Narendran, A.6
Arabian, A.7
Wakeham, A.8
Paige, C.J.9
Zinkernagel, R.M.10
Miller, R.G.11
Mak, T.W.12
-
81
-
-
0025906133
-
CD8 is needed for development of cytotoxic T cells but not helper T cells
-
Fung Leung WP, Schilham MW, Rahemtulla A, Kundig TM, Vollenweider M, Potter J, van Ewijk W, Mak TW. 1991. CD8 is needed for development of cytotoxic T cells but not helper T cells. Cell 65:443-49
-
(1991)
Cell
, vol.65
, pp. 443-449
-
-
Fung Leung, W.P.1
Schilham, M.W.2
Rahemtulla, A.3
Kundig, T.M.4
Vollenweider, M.5
Potter, J.6
Van Ewijk, W.7
Mak, T.W.8
-
82
-
-
0027460824
-
Regulated expression of human CD4 rescues helper T cell development in mice lacking expression of endogenous CD4
-
Killeen N, Sawada S, Littman DR. 1993. Regulated expression of human CD4 rescues helper T cell development in mice lacking expression of endogenous CD4. EMBO J. 12:1547-53
-
(1993)
EMBO J.
, vol.12
, pp. 1547-1553
-
-
Killeen, N.1
Sawada, S.2
Littman, D.R.3
-
83
-
-
0025770184
-
Negative and positive selection of antigen-specific cytotoxic T lymphocytes affected by the alpha 3 domain of MHC I molecules
-
Aldrich CJ, Hammer RE, Jones Young-blood S, Koszinowski U, Hood L, Stroynowski I, Forman J. 1991. Negative and positive selection of antigen-specific cytotoxic T lymphocytes affected by the alpha 3 domain of MHC I molecules. Nature 352:718-21
-
(1991)
Nature
, vol.352
, pp. 718-721
-
-
Aldrich, C.J.1
Hammer, R.E.2
Jones Young-blood, S.3
Koszinowski, U.4
Hood, L.5
Stroynowski, I.6
Forman, J.7
-
84
-
-
0025915619
-
Co-engagement of CD8 with the T cell receptor is required for negative selection
-
Ingold AL, Landel C, Knall C, Evans GA, Potter TA. 1991. Co-engagement of CD8 with the T cell receptor is required for negative selection. Nature 352:721-23
-
(1991)
Nature
, vol.352
, pp. 721-723
-
-
Ingold, A.L.1
Landel, C.2
Knall, C.3
Evans, G.A.4
Potter, T.A.5
-
85
-
-
0026632968
-
Requirement for CD8-major histocompatibility complex class I interaction in positive and negative selection of developing T cells
-
Killeen N, Moriarty A, Teh HS, Littman DR. 1992. Requirement for CD8-major histocompatibility complex class I interaction in positive and negative selection of developing T cells. J. Exp. Med. 176:89-97
-
(1992)
J. Exp. Med.
, vol.176
, pp. 89-97
-
-
Killeen, N.1
Moriarty, A.2
Teh, H.S.3
Littman, D.R.4
-
86
-
-
0027432062
-
Distinct requirements of positive and negative selection for selecting cell type and CD8 interaction
-
Schönrich G, Straub G, Muller K-P, Dustin L, Loh DY, Auphan N, Schmitt-Verhulst A-M, Arnold B, Hämmerling GJ. 1993. Distinct requirements of positive and negative selection for selecting cell type and CD8 interaction. J. Immunol. 151:4098-105
-
(1993)
J. Immunol.
, vol.151
, pp. 4098-4105
-
-
Schönrich, G.1
Straub, G.2
Muller, K.-P.3
Dustin, L.4
Loh, D.Y.5
Auphan, N.6
Schmitt-Verhulst, A.-M.7
Arnold, B.8
Hämmerling, G.J.9
-
87
-
-
0027404346
-
CD8 is needed for positive selection but differentially required for negative selection of T cells during thymic ontogeny
-
Fung Leung WP, Wallace VA, Gray D, Sha WC, Pircher H, Teh HS, Loh DY, Mak TW. 1993. CD8 is needed for positive selection but differentially required for negative selection of T cells during thymic ontogeny. Eur. J. Immunol. 23:212-16
-
(1993)
Eur. J. Immunol.
, vol.23
, pp. 212-216
-
-
Fung Leung, W.P.1
Wallace, V.A.2
Gray, D.3
Sha, W.C.4
Pircher, H.5
Teh, H.S.6
Loh, D.Y.7
Mak, T.W.8
-
88
-
-
0026566233
-
An immunological role for the CD8 beta-chain
-
Wheeler CJ, von Hoegen P, Parnes JR. 1992. An immunological role for the CD8 beta-chain. Nature 357:247-49
-
(1992)
Nature
, vol.357
, pp. 247-249
-
-
Wheeler, C.J.1
Von Hoegen, P.2
Parnes, J.R.3
-
89
-
-
0028210684
-
Requirement for CD8 β chain in positive selection of CD8-lineage T cells
-
Nakayama K, Negishi I, Kuida K, Louie MC, Kanagawa O, Nakauchi H, Loh DY. 1994. Requirement for CD8 β chain in positive selection of CD8-lineage T cells. Science 263:1131-33
-
(1994)
Science
, vol.263
, pp. 1131-1133
-
-
Nakayama, K.1
Negishi, I.2
Kuida, K.3
Louie, M.C.4
Kanagawa, O.5
Nakauchi, H.6
Loh, D.Y.7
-
90
-
-
0028467946
-
Disruption of T lymphocyte positive and negative selection in mice lacking the CD8 beta chain
-
Crooks MEC, Littman DR. 1994. Disruption of T lymphocyte positive and negative selection in mice lacking the CD8 beta chain. Immunity. 1:277-86
-
(1994)
Immunity.
, vol.1
, pp. 277-286
-
-
Crooks, M.E.C.1
Littman, D.R.2
-
91
-
-
0027488625
-
Helper T cells without CD4: Control of leishmaniasis in CD4-deficient mice
-
Locksley RM, Reiner SL, Hatam F, Littman DR, Killeen N. 1993. Helper T cells without CD4: control of leishmaniasis in CD4-deficient mice. Science 261:1448-51
-
(1993)
Science
, vol.261
, pp. 1448-1451
-
-
Locksley, R.M.1
Reiner, S.L.2
Hatam, F.3
Littman, D.R.4
Killeen, N.5
-
92
-
-
0026681864
-
Characterization of the lymphocyte activation gene 3-encoded protein. A new ligand for human leukocyte antigen class II antigens
-
Baixeras E, Huard B, Miossec C, Jitsukawa S, Martin M, Hercend T, Auffray C, Triebet F, Piatier Tonneau D. 1992. Characterization of the lymphocyte activation gene 3-encoded protein. A new ligand for human leukocyte antigen class II antigens. J. Exp. Med. 176:327-37
-
(1992)
J. Exp. Med.
, vol.176
, pp. 327-337
-
-
Baixeras, E.1
Huard, B.2
Miossec, C.3
Jitsukawa, S.4
Martin, M.5
Hercend, T.6
Auffray, C.7
Triebet, F.8
Piatier Tonneau, D.9
-
93
-
-
0026034155
-
Thymic selection in CD8 transgenic mice supports an instructive model for commitment to a CD4 or CD8 lineage
-
Robey EA, Fowlkes BJ, Gordon JW, Kioussis D, von Boehmer H, Ramsdell F, Axel R. 1991. Thymic selection in CD8 transgenic mice supports an instructive model for commitment to a CD4 or CD8 lineage. Cell 64:99-107
-
(1991)
Cell
, vol.64
, pp. 99-107
-
-
Robey, E.A.1
Fowlkes, B.J.2
Gordon, J.W.3
Kioussis, D.4
Von Boehmer, H.5
Ramsdell, F.6
Axel, R.7
-
95
-
-
0026522260
-
Signal for T-cell differentiation to a CD4 cell lineage is delivered by CD4 transmembrane region and/or cytoplasmic tail
-
Seong RH, Chamberlain JW, Parnes JR. 1992. Signal for T-cell differentiation to a CD4 cell lineage is delivered by CD4 transmembrane region and/or cytoplasmic tail. Nature 356:718-20
-
(1992)
Nature
, vol.356
, pp. 718-720
-
-
Seong, R.H.1
Chamberlain, J.W.2
Parnes, J.R.3
-
96
-
-
0027515732
-
Thymocyte development in major histocompatibility complex-deficient mice: Evidence for stochastic commitment to the CD4 and CD8 lineages
-
Crump AL, Grusby MJ, Glimcher LH, Cantor H. 1993. Thymocyte development in major histocompatibility complex-deficient mice: evidence for stochastic commitment to the CD4 and CD8 lineages. Proc. Natl. Acad. Sci. USA 90:10739-43
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 10739-10743
-
-
Crump, A.L.1
Grusby, M.J.2
Glimcher, L.H.3
Cantor, H.4
-
98
-
-
0028075391
-
Role of coreceptors in positive selection and lineage commitment
-
Chan SH, Waltzinger C, Baron A, Benoist C, Mathis D. 1994. Role of coreceptors in positive selection and lineage commitment. EMBO J. 13:4482-89
-
(1994)
EMBO J.
, vol.13
, pp. 4482-4489
-
-
Chan, S.H.1
Waltzinger, C.2
Baron, A.3
Benoist, C.4
Mathis, D.5
-
102
-
-
0028467791
-
Functional commitment to helper T cell lineage precedes positive selection and is independent of T cell receptor MHC specificity
-
Corbella P, Spanopoulou, Moskophidis D, Mamalaki C, Tolaini M, A, Lans D, Baltimore D, Robey E, Kioussis D. 1994. Functional commitment to helper T cell lineage precedes positive selection and is independent of T cell receptor MHC specificity. Immunity 1:269-76
-
(1994)
Immunity
, vol.1
, pp. 269-276
-
-
Corbella, P.1
Spanopoulou2
Moskophidis, D.3
Mamalaki, C.4
Tolaini, M.A.5
Lans, D.6
Baltimore, D.7
Robey, E.8
Kioussis, D.9
-
104
-
-
0027729845
-
Uncovering of functional alternative CTLA-4 counter-receptor in B7-deficient mice
-
Freeman GJ, Borriello F, Modes RJ, Reiser H, Hathcock KS, Laszlo G, McKnight AJ, Kim J, Du L, Lombard DB, Nadler LM, Sharpe AH. 1993. Uncovering of functional alternative CTLA-4 counter-receptor in B7-deficient mice. Science 262:907-9
-
(1993)
Science
, vol.262
, pp. 907-909
-
-
Freeman, G.J.1
Borriello, F.2
Modes, R.J.3
Reiser, H.4
Hathcock, K.S.5
Laszlo, G.6
McKnight, A.J.7
Kim, J.8
Du, L.9
Lombard, D.B.10
Nadler, L.M.11
Sharpe, A.H.12
-
105
-
-
0027281691
-
Differential T cell costimulatory requirements in CD28-deficient mice
-
Shahinian A, Pfeffer K, Lee KP, Kundig TM, Kishihara K, Wakeham A, Kawai K, Ohashi PS, Thompson CB, Mak TW. 1993. Differential T cell costimulatory requirements in CD28-deficient mice. Science 261:609-12
-
(1993)
Science
, vol.261
, pp. 609-612
-
-
Shahinian, A.1
Pfeffer, K.2
Kp, L.3
Kundig, T.M.4
Kishihara, K.5
Wakeham, A.6
Kawai, K.7
Ohashi, P.S.8
Thompson, C.B.9
Mak, T.W.10
-
106
-
-
0027302420
-
CD28-B7 interactions are not required for intrathymic clonal deletion
-
Jones LA, Izon DJ, Nieland JD, Linsley PS, Kruisbeek AM. 1993. CD28-B7 interactions are not required for intrathymic clonal deletion. Int. Immunol. 5:503-12
-
(1993)
Int. Immunol.
, vol.5
, pp. 503-512
-
-
Jones, L.A.1
Izon, D.J.2
Nieland, J.D.3
Linsley, P.S.4
Kruisbeek, A.M.5
-
107
-
-
0028202939
-
A positively selecting thymic epithelial cell line lacks costimulatory activity
-
Vukmanović S, Stella G, King PD, Dyall R, Hogquist KA, Harty JT, Nikolić Zugić J, Bevan MJ. 1994. A positively selecting thymic epithelial cell line lacks costimulatory activity. J. Immunol. 152:3814-23
-
(1994)
J. Immunol.
, vol.152
, pp. 3814-3823
-
-
Vukmanović, S.1
Stella, G.2
King, P.D.3
Dyall, R.4
Hogquist, K.A.5
Harty, J.T.6
Nikolić Zugić, J.7
Bevan, M.J.8
-
108
-
-
0028115823
-
Defective development of thymocytes overexpressing the costimulatory molecule, heat-stable antigen
-
Hough MR, Takei F, Humphries RK, KayR. 1994. Defective development of thymocytes overexpressing the costimulatory molecule, heat-stable antigen. J. Exp. Med. 179:177-84
-
(1994)
J. Exp. Med.
, vol.179
, pp. 177-184
-
-
Hough, M.R.1
Takei, F.2
Humphries, R.K.3
Kay, R.4
-
109
-
-
0028288927
-
The role of protein tyrosine kinases and protein tyrosine phophatases in T cell antigen receptor signal transduction
-
Chan AC, Desai DM, Weiss A. 1994. The role of protein tyrosine kinases and protein tyrosine phophatases in T cell antigen receptor signal transduction. Annu. Rev. Immunol. 12:555-92
-
(1994)
Annu. Rev. Immunol.
, vol.12
, pp. 555-592
-
-
Chan, A.C.1
Desai, D.M.2
Weiss, A.3
-
110
-
-
0027461317
-
Regulation of lymphocyte function by protein phosphorylation
-
Perlmutter RM, Levin SD, Appleby MW, Anderson SJ, Alberola-Ila J. 1993. Regulation of lymphocyte function by protein phosphorylation. Annu. Rev. Immunol. 11:451-99
-
(1993)
Annu. Rev. Immunol.
, vol.11
, pp. 451-499
-
-
Perlmutter, R.M.1
Levin, S.D.2
Appleby, M.W.3
Anderson, S.J.4
Alberola-Ila, J.5
-
111
-
-
0023680294
-
Effects of cyclosporine A on T cell development and clonal deletion
-
Jenkins MK, Schwartz RH, Pardoll DM. 1988. Effects of cyclosporine A on T cell development and clonal deletion. Science 241:1655-58
-
(1988)
Science
, vol.241
, pp. 1655-1658
-
-
Jenkins, M.K.1
Schwartz, R.H.2
Pardoll, D.M.3
-
112
-
-
0023794047
-
Abnormal differentiation of thymocytes in mice treated with cyclosporin A
-
Gao EK, Lo D, Cheney R, Kanagawa O, Sprent J. 1988. Abnormal differentiation of thymocytes in mice treated with cyclosporin A. Nature 336:176-79
-
(1988)
Nature
, vol.336
, pp. 176-179
-
-
Gao, E.K.1
Lo, D.2
Cheney, R.3
Kanagawa, O.4
Sprent, J.5
-
113
-
-
0028297669
-
Cyclosporin A inhibits positive selection and delays negative selection in alpha beta TCR transgenic mice
-
Urdahl KB, Pardoll DM, Jenkins MK. 1994. Cyclosporin A inhibits positive selection and delays negative selection in alpha beta TCR transgenic mice. J. Immunol. 152:2853-59
-
(1994)
J. Immunol.
, vol.152
, pp. 2853-2859
-
-
Urdahl, K.B.1
Pardoll, D.M.2
Jenkins, M.K.3
-
114
-
-
0025752347
-
Regulation of T cell receptor signaling by a src family protein-tyrosine kinase (p59fyn)
-
Cooke MP, Abraham KM, Forbush KA, Perlmutter RM. 1991. Regulation of T cell receptor signaling by a src family protein-tyrosine kinase (p59fyn). Cell 65:281-91
-
(1991)
Cell
, vol.65
, pp. 281-291
-
-
Cooke, M.P.1
Abraham, K.M.2
Forbush, K.A.3
Perlmutter, R.M.4
-
115
-
-
0026669001
-
Defective T cell receptor signaling in mice lacking the thymic isoform of p59fyn
-
Appleby MW, Gross JA, Cooke MP, Levin SD, Qian X, Perlmutter RM. 1992. Defective T cell receptor signaling in mice lacking the thymic isoform of p59fyn. Cell 70:751-63
-
(1992)
Cell
, vol.70
, pp. 751-763
-
-
Appleby, M.W.1
Gross, J.A.2
Cooke, M.P.3
Levin, S.D.4
Qian, X.5
Perlmutter, R.M.6
-
116
-
-
0026612411
-
fyn mutant mice display differential signaling in thymocytes and peripheral T cells
-
fyn mutant mice display differential signaling in thymocytes and peripheral T cells. Cell 70:741-50
-
(1992)
Cell
, vol.70
, pp. 741-750
-
-
Stein, P.L.1
Lee, H.M.2
Rich, S.3
Soriano, P.4
-
118
-
-
0028340167
-
ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency
-
Chan AC, Kadlecek TA, Elder ME, Filipovich AH, Kuo W-L, Iwashima M, Parslow TG, Weiss A. 1994. ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency. Science 264:1599-601
-
(1994)
Science
, vol.264
, pp. 1599-1601
-
-
Chan, A.C.1
Kadlecek, T.A.2
Elder, M.E.3
Filipovich, A.H.4
Kuo, W.-L.5
Iwashima, M.6
Parslow, T.G.7
Weiss, A.8
-
119
-
-
0028292001
-
Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase
-
Elder ME, Lin D, Clever J, Chan AC, Hope TJ, Weiss A, Parslow TG. 1994. Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase. Science 264:1596-99
-
(1994)
Science
, vol.264
, pp. 1596-1599
-
-
Elder, M.E.1
Lin, D.2
Clever, J.3
Chan, A.C.4
Hope, T.J.5
Weiss, A.6
Parslow, T.G.7
-
120
-
-
0028216232
-
Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signaling
-
Chan AC, van Oers NS, Tran A, Turka L, Law CL, Ryan JC, Clark EA, Weiss A. 1994. Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signaling. J. Immunol. 152:4758-66
-
(1994)
J. Immunol.
, vol.152
, pp. 4758-4766
-
-
Chan, A.C.1
Van Oers, N.S.2
Tran, A.3
Turka, L.4
Law, C.L.5
Ryan, J.C.6
Clark, E.A.7
Weiss, A.8
-
121
-
-
0027361463
-
Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development
-
Matsuyama T, Kimura T, Kitagawa M, Pfeffer K, Kawakami T, Watanabe N, Kundig TM, Amakawa R, Kishihara K, Wakeham A, Potter J, Furlonger CL, Narendran A, Suzuki H, Ohashi PS, Taniguchi T, Mak TW. 1993. Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development. Cell 75:83-97
-
(1993)
Cell
, vol.75
, pp. 83-97
-
-
Matsuyama, T.1
Kimura, T.2
Kitagawa, M.3
Pfeffer, K.4
Kawakami, T.5
Watanabe, N.6
Kundig, T.M.7
Amakawa, R.8
Kishihara, K.9
Wakeham, A.10
Potter, J.11
Furlonger, C.L.12
Narendran, A.13
Suzuki, H.14
Ohashi, P.S.15
Taniguchi, T.16
Mak, T.W.17
-
122
-
-
0026522204
-
lck
-
lck. Nature 357:161-64
-
(1992)
Nature
, vol.357
, pp. 161-164
-
-
Molina, T.J.1
Kishihara, K.2
Siderovski, D.P.3
Van Ewijk, W.4
Narendran, A.5
Timms, E.6
Wakeham, A.7
Paige, C.J.8
Hartmann, K.U.9
Veillette, A.10
Davidson, D.11
Mak, T.W.12
-
126
-
-
0024807506
-
Engagement of CD4 and CD8 expressed on immature thymocytes induces activation of intracellular tyrosine phosphorylation pathways
-
Veillette A, Zuniga Pflucker JC, Bolen JB, Kruisbeek AM. 1989. Engagement of CD4 and CD8 expressed on immature thymocytes induces activation of intracellular tyrosine phosphorylation pathways. J. Exp. Med. 170:1671-80
-
(1989)
J. Exp. Med.
, vol.170
, pp. 1671-1680
-
-
Veillette, A.1
Zuniga Pflucker, J.C.2
Bolen, J.B.3
Kruisbeek, A.M.4
-
127
-
-
0027379699
-
lck tyrosine kinase: Basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules
-
lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules. J. Exp. Med. 178:1701-12
-
(1993)
J. Exp. Med.
, vol.178
, pp. 1701-1712
-
-
Wiest, D.L.1
Yuan, L.2
Jefferson, J.3
Benveniste, P.4
Tsokos, M.5
Klausner, R.D.6
Glimcher, L.H.7
Samelson, L.E.8
Singer, A.9
-
129
-
-
0027501143
-
Thymic selection of cytotoxic T cells independent of CD8 alpha-Lck association
-
Chan IT, Limmer A, Louie MC, Bullock ED, Fung Leung WP, Mak TW, Loh DY. 1993. Thymic selection of cytotoxic T cells independent of CD8 alpha-Lck association. Science 261:1581-84
-
(1993)
Science
, vol.261
, pp. 1581-1584
-
-
Chan, I.T.1
Limmer, A.2
Louie, M.C.3
Bullock, E.D.4
Fung Leung, W.P.5
Mak, T.W.6
Loh, D.Y.7
-
130
-
-
0027366168
-
+ T lymphocytes
-
+ T lymphocytes. Eur. J. Immunol. 23:2834-40
-
(1993)
Eur. J. Immunol.
, vol.23
, pp. 2834-2840
-
-
Fung Leung, W.P.1
Louie, M.C.2
Limmer, A.3
Ohashi, P.S.4
Ngo, K.5
Chen, L.6
Kawai, K.7
Lacy, E.8
Loh, D.Y.9
Mak, T.W.10
-
131
-
-
0027257445
-
A kinase-independent function of Lck in potentiating antigen-specific T cell activation
-
Xu H, Littman DR. 1993. A kinase-independent function of Lck in potentiating antigen-specific T cell activation. Cell 74:633-43
-
(1993)
Cell
, vol.74
, pp. 633-643
-
-
Xu, H.1
Littman, D.R.2
-
133
-
-
0028346560
-
CD45: An emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development
-
Trowbridge IS, Thomas ML. 1994. CD45: An emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development. Annu. Rev. Immunol. 12:85-116
-
(1994)
Annu. Rev. Immunol.
, vol.12
, pp. 85-116
-
-
Trowbridge, I.S.1
Thomas, M.L.2
-
134
-
-
0027296521
-
Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice
-
Kishihara K, Penninger J, Wallace VA, Kundig TM, Kawai K, Wakeham A, Timms E, Pfeffer K, Ohashi PS, Thomas ML, Furlonger C, Paige CJ, Mak TW. 1993. Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice. Cell 74:143-56
-
(1993)
Cell
, vol.74
, pp. 143-156
-
-
Kishihara, K.1
Penninger, J.2
Wallace, V.A.3
Kundig, T.M.4
Kawai, K.5
Wakeham, A.6
Timms, E.7
Pfeffer, K.8
Ohashi, P.S.9
Thomas, M.L.10
Furlonger, C.11
Paige, C.J.12
Mak, T.W.13
-
135
-
-
0025021670
-
Role of self-peptides in positively selecting the T-cell repertoire
-
Nikolić Zugić J, Bevan MJ. 1990. Role of self-peptides in positively selecting the T-cell repertoire. Nature 344:65-67
-
(1990)
Nature
, vol.344
, pp. 65-67
-
-
Nikolić Zugić, J.1
Bevan, M.J.2
-
136
-
-
0025327432
-
The effects of MHC gene dosage and allelic variation on T cell receptor selection
-
Berg LJ, Frank GD, Davis MM. 1990. The effects of MHC gene dosage and allelic variation on T cell receptor selection. Cell 60:1043-53
-
(1990)
Cell
, vol.60
, pp. 1043-1053
-
-
Berg, L.J.1
Frank, G.D.2
Davis, M.M.3
-
137
-
-
0025150378
-
Positive selection of transgenic receptor-bearing thymocytes by Kb antigen is altered by Kb mutations that involve peptide binding
-
Sha WC, Nelson CA, Newberry RD, Pullen JK, Pease LR, Russell JH, Loh DY. 1990. Positive selection of transgenic receptor-bearing thymocytes by Kb antigen is altered by Kb mutations that involve peptide binding. Proc. Natl. Acad. Sci. USA 87:6186-90
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 6186-6190
-
-
Sha, W.C.1
Nelson, C.A.2
Newberry, R.D.3
Pullen, J.K.4
Pease, L.R.5
Russell, J.H.6
Loh, D.Y.7
-
138
-
-
0025039033
-
Mutations in the major histocompatibility complex class I antigen-presenting groove affect both negative and positive selection of T cells
-
Jacobs H, von Boehmer H, Melief CJ, Berns A. 1990. Mutations in the major histocompatibility complex class I antigen-presenting groove affect both negative and positive selection of T cells. Eur. J. Immunol. 20:2333-37
-
(1990)
Eur. J. Immunol.
, vol.20
, pp. 2333-2337
-
-
Jacobs, H.1
Von Boehmer, H.2
Melief, C.J.3
Berns, A.4
-
139
-
-
0027400357
-
Enhanced positive selection of a transgenic TCR by a restriction element that does not permit negative selection
-
Ohashi PS, Zinkernagel RM, Leuscher I, Hengartner H, Pircher H. 1993. Enhanced positive selection of a transgenic TCR by a restriction element that does not permit negative selection. Int. Immunol. 5:131-38
-
(1993)
Int. Immunol.
, vol.5
, pp. 131-138
-
-
Ohashi, P.S.1
Zinkernagel, R.M.2
Leuscher, I.3
Hengartner, H.4
Pircher, H.5
-
141
-
-
0028038426
-
MHC-dependent antigen processing and peptide presentation: Providing ligands for T lymphocyte activation
-
Germain RN. 1994. MHC-dependent antigen processing and peptide presentation: providing ligands for T lymphocyte activation. Cell 76:287-99
-
(1994)
Cell
, vol.76
, pp. 287-299
-
-
Germain, R.N.1
-
142
-
-
0025609606
-
The role of beta 2-microglobulin in peptide binding by class 1 molecules
-
Vitiello A, Potter TA, Sherman LA. 1990. The role of beta 2-microglobulin in peptide binding by class 1 molecules. Science 250:1423-26
-
(1990)
Science
, vol.250
, pp. 1423-1426
-
-
Vitiello, A.1
Potter, T.A.2
Sherman, L.A.3
-
143
-
-
0027478380
-
+ T cells induced by major histocompatibility complex binding peptides in fetal thymic organ culture
-
+ T cells induced by major histocompatibility complex binding peptides in fetal thymic organ culture. J. Exp. Med. 177:1469-73
-
(1993)
J. Exp. Med.
, vol.177
, pp. 1469-1473
-
-
Hogquist, K.A.1
Gavin, M.A.2
Bevan, M.J.3
-
145
-
-
0028215702
-
The ligand for positive selection of T lymphocytes in the thymus
-
Hogquist KA, Jameson SC, Bevan MJ. 1994. The ligand for positive selection of T lymphocytes in the thymus. Curr. Opp. Immunol. 6:273-78
-
(1994)
Curr. Opp. Immunol.
, vol.6
, pp. 273-278
-
-
Hogquist, K.A.1
Jameson, S.C.2
Bevan, M.J.3
-
146
-
-
0028178784
-
T cell receptor antagonist peptides induce positive selection
-
Hogquist KA, Jameson SC, Heath WR, Howard JL, Bevan MJ, Carbone FR. 1994. T cell receptor antagonist peptides induce positive selection. Cell 76:17-27
-
(1994)
Cell
, vol.76
, pp. 17-27
-
-
Hogquist, K.A.1
Jameson, S.C.2
Heath, W.R.3
Howard, J.L.4
Bevan, M.J.5
Carbone, F.R.6
-
147
-
-
0028273017
-
Evidence for a differential avidity model of T cell selection in the thymus
-
Ashton-Rickardt PG, Bandeira A, Delaney JR, Van Kaer L, Pircher H-P, Zinkernagel RM, Tonegawa S. 1994. Evidence for a differential avidity model of T cell selection in the thymus. Cell 76:651-63
-
(1994)
Cell
, vol.76
, pp. 651-663
-
-
Ashton-Rickardt, P.G.1
Bandeira, A.2
Delaney, J.R.3
Van Kaer, L.4
Pircher, H.-P.5
Zinkernagel, R.M.6
Tonegawa, S.7
-
148
-
-
0028294682
-
Positive and negative thymocyte selection induced by different concentration of a single peptide
-
Sebzda E, Wallace VA, Mayer J, Yeung RSM, Mak TW, Ohashi PS. 1994. Positive and negative thymocyte selection induced by different concentration of a single peptide. Science 263:1615-18
-
(1994)
Science
, vol.263
, pp. 1615-1618
-
-
Sebzda, E.1
Wallace, V.A.2
Mayer, J.3
Yeung, R.S.M.4
Mak, T.W.5
Ohashi, P.S.6
-
149
-
-
0028238668
-
Specificity and flexibility in thymic selection
-
Jameson SC, Hogquist KA, Bevan MJ. 1994. Specificity and flexibility in thymic selection. Nature 369:750-52
-
(1994)
Nature
, vol.369
, pp. 750-752
-
-
Jameson, S.C.1
Hogquist, K.A.2
Bevan, M.J.3
-
151
-
-
0027205194
-
Clone-specific T cell receptor antagonists of major histocompatibility complex class I-restricted cytotoxic T cells
-
Jameson SC, Carbone FR, Bevan MJ. 1993. Clone-specific T cell receptor antagonists of major histocompatibility complex class I-restricted cytotoxic T cells. J. Exp. Med. 177:1541-50
-
(1993)
J. Exp. Med.
, vol.177
, pp. 1541-1550
-
-
Jameson, S.C.1
Carbone, F.R.2
Bevan, M.J.3
-
152
-
-
0028281677
-
A peptide antigen antagonist prevents the differentiation of T cell receptor transgenic thymocytes
-
Spain LM, Jorgensen JL, Davis MM, Berg LJ. 1994. A peptide antigen antagonist prevents the differentiation of T cell receptor transgenic thymocytes. J. Immunol. 152:1709-17
-
(1994)
J. Immunol.
, vol.152
, pp. 1709-1717
-
-
Spain, L.M.1
Jorgensen, J.L.2
Davis, M.M.3
Berg, L.J.4
-
154
-
-
0026607073
-
CD8 surface levels alter the fate of alpha/beta T cell receptor-expressing thymocytes in transgenic mice
-
Lee NA, Loh DY, Lacy E. 1992. CD8 surface levels alter the fate of alpha/beta T cell receptor-expressing thymocytes in transgenic mice. J. Exp. Med. 175:1013-25
-
(1992)
J. Exp. Med.
, vol.175
, pp. 1013-1025
-
-
Lee, N.A.1
Loh, D.Y.2
Lacy, E.3
-
155
-
-
0026633043
-
The level of CD8 expression can determine the outcome of thymic selection
-
Robey EA, Ramsdell F, Kioussis D, Sha W, Loh D, Axel R, Fowlkes BJ. 1992. The level of CD8 expression can determine the outcome of thymic selection. Cell 69:1089-96
-
(1992)
Cell
, vol.69
, pp. 1089-1096
-
-
Robey, E.A.1
Ramsdell, F.2
Kioussis, D.3
Sha, W.4
Loh, D.5
Axel, R.6
Fowlkes, B.J.7
-
156
-
-
0026714365
-
Threshold tolerance in H-2Kb-specific TCR transgenic mice expressing mutant H-2Kb: Conversion of helper-independent to helper-dependent CTL
-
Auphan N, Jezo-Bremond A, Schönrich G, HämmerlingG, Arnold B, Malissen B, Schmitt-Verhulst A-M. 1992. Threshold tolerance in H-2Kb-specific TCR transgenic mice expressing mutant H-2Kb: conversion of helper-independent to helper-dependent CTL. Int. Immunol. 4:1419-28
-
(1992)
Int. Immunol.
, vol.4
, pp. 1419-1428
-
-
Auphan, N.1
Jezo-Bremond, A.2
Schönrich, G.3
Hämmerling, G.4
Arnold, B.5
Malissen, B.6
Schmitt-Verhulst, A.-M.7
-
157
-
-
0026582750
-
Influence of antigen density on degree of clonal deletion in T cell receptor transgenic mice
-
Auphan N, Schönrich G, Malissen M, Barad M, Hämmerling G, Arnold B, Malissen B, Schmitt Verhulst AM. 1992. Influence of antigen density on degree of clonal deletion in T cell receptor transgenic mice. Int. Immunol. 4:541-47
-
(1992)
Int. Immunol.
, vol.4
, pp. 541-547
-
-
Auphan, N.1
Schönrich, G.2
Malissen, M.3
Barad, M.4
Hämmerling, G.5
Arnold, B.6
Malissen, B.7
Schmitt Verhulst, A.M.8
-
159
-
-
0027497957
-
+, alpha beta T-cell receptor cytotoxic T cells with major histocompatibility complex (MHC) class I antigen-directed cytotoxicity in beta 2-microglobulin MHC class I-deficient mice
-
+, alpha beta T-cell receptor cytotoxic T cells with major histocompatibility complex (MHC) class I antigen-directed cytotoxicity in beta 2-microglobulin MHC class I-deficient mice. Proc. Natl. Acad. Sci. USA 90:2837-41
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 2837-2841
-
-
Apasov, S.1
Sitkovsky, M.2
-
160
-
-
0028091278
-
+ T cell repertoire in beta 2-microglobulin-deficient mice is biased towards reactivity against self-major histocompatibility class I
-
+ T cell repertoire in beta 2-microglobulin-deficient mice is biased towards reactivity against self-major histocompatibility class I. J. Exp. Med. 179:661-72
-
(1994)
J. Exp. Med.
, vol.179
, pp. 661-672
-
-
Glas, R.1
Öhlen, C.2
Höglund, P.3
Kärre, K.4
-
163
-
-
0026463035
-
Selecting T cell receptors with high affinity for self-MHC by decreasing the contribution of CD8
-
Sherman LA, Hesse SV, Irwin MJ, La Face D, Peterson P. 1992. Selecting T cell receptors with high affinity for self-MHC by decreasing the contribution of CD8. Science 258:815-18
-
(1992)
Science
, vol.258
, pp. 815-818
-
-
Sherman, L.A.1
Hesse, S.V.2
Irwin, M.J.3
La Face, D.4
Peterson, P.5
-
164
-
-
0025855156
-
Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules
-
Falk K, Rötzschke O, Stevanović S, Jung G, Rammensee HG. 1991. Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules. Nature 351:290-96
-
(1991)
Nature
, vol.351
, pp. 290-296
-
-
Falk, K.1
Rötzschke, O.2
Stevanović, S.3
Jung, G.4
Rammensee, H.G.5
-
166
-
-
0027447575
-
Immune discrimination of self and nonself: A unified theory for the induction of self tolerance among thymocytes and mature peripheral T cells
-
Mannie MD. 1993. Immune discrimination of self and nonself: a unified theory for the induction of self tolerance among thymocytes and mature peripheral T cells. Med. Hypotheses 40:105-12
-
(1993)
Med. Hypotheses
, vol.40
, pp. 105-112
-
-
Mannie, M.D.1
-
167
-
-
0026503161
-
Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor
-
De Magistris MT, Alexander J, Coggeshall M, Altman A, Gaeta FC, Grey HM, Sette A. 1992. Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor. Cell 68:625-34
-
(1992)
Cell
, vol.68
, pp. 625-634
-
-
De Magistris, M.T.1
Alexander, J.2
Coggeshall, M.3
Altman, A.4
Gaeta, F.C.5
Grey, H.M.6
Sette, A.7
-
169
-
-
0026632418
-
+ cytotoxic T lymphocytes in association with a class I MHC protein
-
+ cytotoxic T lymphocytes in association with a class I MHC protein. Cell 69:989-98
-
(1992)
Cell
, vol.69
, pp. 989-998
-
-
Udaka, K.1
Tsomides, T.J.2
Eisen, H.N.3
-
170
-
-
0028410566
-
Kinetics and affinity of reactions between and antigen-specific T cell receptor and peptide-MHC complexes
-
Sykulev Y, Brunmark A, Jackson M, Cohen RJ, Peterson PA, Eisen HN. 1994. Kinetics and affinity of reactions between and antigen-specific T cell receptor and peptide-MHC complexes. Immunity 1:15-22
-
(1994)
Immunity
, vol.1
, pp. 15-22
-
-
Sykulev, Y.1
Brunmark, A.2
Jackson, M.3
Cohen, R.J.4
Peterson, P.A.5
Eisen, H.N.6
-
171
-
-
0023724209
-
Positive and negative selection of an antigen receptor on T cells in transgenic mice
-
Sha WC, Nelson CA,Newberry RD, Kranz DM, Russell JH, Loh DY. 1988. Positive and negative selection of an antigen receptor on T cells in transgenic mice. Nature 336:73-76
-
(1988)
Nature
, vol.336
, pp. 73-76
-
-
Sha, W.C.1
Nelson, C.A.2
Newberry, R.D.3
Kranz, D.M.4
Russell, J.H.5
Loh, D.Y.6
-
172
-
-
0025357975
-
Characterization of naturally occurring minor histocompatibility peptides including H-4 and H-Y
-
Rötzschke O, Falk K, Wallny HJ, Faath S, Rammensee HG. 1990. Characterization of naturally occurring minor histocompatibility peptides including H-4 and H-Y. Science 249:283-87
-
(1990)
Science
, vol.249
, pp. 283-287
-
-
Rötzschke, O.1
Falk, K.2
Wallny, H.J.3
Faath, S.4
Rammensee, H.G.5
-
173
-
-
0025155682
-
Cellular peptide composition governed by major histocompatibility complex class I molecules
-
Falk K, Rötzschke O, Rammensee HG. 1990. Cellular peptide composition governed by major histocompatibility complex class I molecules. Nature 348:248-51
-
(1990)
Nature
, vol.348
, pp. 248-251
-
-
Falk, K.1
Rötzschke, O.2
Rammensee, H.G.3
-
174
-
-
0025944429
-
Exact prediction of a natural T cell epitope
-
Rötzschke O, Falk K, Stevanović S, Jung G, Walden P, Rammensee HG. 1991. Exact prediction of a natural T cell epitope. Eur. J. Immunol. 21:2891-94
-
(1991)
Eur. J. Immunol.
, vol.21
, pp. 2891-2894
-
-
Rötzschke, O.1
Falk, K.2
Stevanović, S.3
Jung, G.4
Walden, P.5
Rammensee, H.G.6
|