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3
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0026327423
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Hoyer, D.; Clarke D. E.; Fozard, J. R.; Hartig, P. R.; Martin, G. R.; Mylecharane, E. J.; Saxena, P. R.; Humphrey, P. P. A. Pharmacol. Rev. 1994, 46, 157.
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For example, synthetic work has focused on the preparation of serotonin mimics exhibiting locked conformations or bearing additional functionality to probe receptor site selectivity
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For example, synthetic work has focused on the preparation of serotonin mimics exhibiting locked conformations or bearing additional functionality to probe receptor site selectivity: Swain, C. J.; Baker, R.; Kneen, C.; Herbert, R.; Moseley, J.; Saunders, J.; Seward, E. M.; Stevenson, G. I.; Beer, M.; Stanton, J.; Watling, K.; Ball, R. G. J. Med. Chem. 1992, 35, 1019.
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85022477173
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2/DMF; 2. 10% Pd/C/toluene/H2, 1 atm and silylation (NaH/TBSCl) to afford the product in 63% overall yield without chromatography
-
2/DMF; 2. 10% Pd/C/toluene/H2, 1 atm (Org. Synth. 1986, 63, 214) and silylation (NaH/TBSCl) to afford the product in 63% overall yield without chromatography.
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18
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0004571867
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Brossi, A., Ed.; Academic Press: New York
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0001052366
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4-Hydroxy- and 4-aminoindoles are structural components of psylocibin and teleocidin alkaloids; see and references cited therein
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4-Hydroxy- and 4-aminoindoles are structural components of psylocibin and teleocidin alkaloids; see: Nakatsuka, S.-I.; Masuda, T.; Asano, O.; Teramae, T.; Goto, T. Tetrahedron Lett. 1986, 27, 4327 and references cited therein.
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37049088711
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For the Li to Sn transmetalation method for s-electrophile introduction, see
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For the Li to Sn transmetalation method for s-electrophile introduction, see: Dickens, M. J.; Mowlem, T. J.; Widdowson, D. A.; Slawin, A. M. Z.; Williams, D. J. J. Chem. Soc, Perkin Trans. 1 1992, 323.
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85010134011
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3/DMEZreflux) on 4, E = Li, afforded the analogous cross-coupled product with loss of TBS in 19% yield. For other low yield couplings of pyridyl boron derivatives with 4-iodo- and 4-thallioindoles, see
-
3/DMEZreflux) on 4, E = Li, afforded the analogous cross-coupled product with loss of TBS in 19% yield. For other low yield couplings of pyridyl boron derivatives with 4-iodo- and 4-thallioindoles, see: Somei, M.; Amari, H.; Makita, Y. Chem. Pharm. Bull. Jpn. 1986, 34, 3971.
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0042733411
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2 to give 9a, 9b, and 9c, respectively. Inter alia, this may allow the preparation of 5-hy-droxytryptamine analogues. TBS (22) For a crystal structure of serotonin see
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2 to give 9a, 9b, and 9c, respectively. Inter alia, this may allow the preparation of 5-hy-droxytryptamine analogues. TBS (22) For a crystal structure of serotonin see: Bugg, C. E.; Thewalt U. Acta Crystallogr. Sect. B 1972, 28, 82.
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