Regiospecific synthesis of unsymmetrical α-bromoketones

Synthetic Communications

Volumn 25, Issue 7, 1995, Pages 1045-1051

  Boyd, Robert E ^a   Rasmussen, C Royce ^a   Press, Jeffery B ^a  

^a R W JOHNSON PHARMACEUTICAL RES I   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA BROMOKETONE; KETONE; ORGANOBROMINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; METHODOLOGY; REACTION ANALYSIS;

EID: 0028902066     PISSN: 00397911     EISSN: 15322432     Source Type: Journal    
DOI: 10.1080/00397919508012666     Document Type: Article

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18. In some cases, most notably 4e and 4f hydrolysis and decarboxylation was accompanied by some scrambling of the bromine. This could be minimized (<5%) by addition of the bromoketoester to a refluxing solution solution of
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