In vivo adenovirus-mediated gene transfer via the pulmonary artery of rats

Circulation Research

Volumn 76, Issue 5, 1995, Pages 701-709

  Schachtner, Susan K ^c   Rome, Jonathan J ^c   Hoyt Jr , Robert F ^a   Newman, Kurt D ^c   Virmani, Renu ^b   Dichek, David A ^a,d  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b ARMED FORCES INSTITUTE OF PATHOLOGY   (United States)

^c CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

adenovirus; gene therapy; gene transfer; pulmonary artery; pulmonary hypertension

Indexed keywords

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; GENE EXPRESSION; GENE TRANSFER; LUNG ALVEOLUS EPITHELIUM; LUNG ALVEOLUS MACROPHAGE; LUNG ENDOTHELIUM; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY; PULMONARY ARTERY OCCLUSION; PULMONARY HYPERTENSION; PULMONARY VEIN OBSTRUCTION; RAT; SMOOTH MUSCLE FIBER;

EID: 0028901623     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.76.5.701     Document Type: Article

References (49)

1. Enson Y, Giuntini D, Lewis ML, Morris TQ, Ferrer MI, Harvey RM. The influence of hydrogen ion concentration and hypoxia on the pulmonary circulation. J Clin Invest. 1964;6:1146-1161.
2. Tucker A, Weir EK, Reeves JT, Graver RF. Histamine H-1 and H-2 receptors in pulmonary and systemic vasculature of the dog. Am J Physiol. 1975;229:1008-1013.
3. Roberts JD, Shaul PW. Advances in the treatment of persistent pulmonary hypertension of the newborn. Pediatr Clin North Am. 1993;40:983-1004.
4. Houde C, Bohn DJ, Freedom RM, Rabinovitch M. Profile of paediatric patients with pulmonary hypertension judged by responsiveness to vasodilators. Br Heart J. 1993;70:461-468.
5. Roberts JD, Lang P, Bigatello LM, Vlahakes GJ, Zapol WM. Inhaled nitric oxide in congenital heart disease. Circulation. 1993; 87:447-453.
6. Collins-Nakai RL, Rabinovitch M. Pulmonary vascular obstructive disease. Cardiol Clin, 1993;11:675-687.
7. Elton TS, Oparil S, Taylor GR, Hicks PH, Yang R, Jin H, Chen YF. Normobaric hypoxia stimulates endothelin-1 gene expression in the rat. Am J Physiol. 1992;263:R1260-R1264.
8. Stelzner TJ, O'Brien RF, Yanagisawa M, Sakurai T, Sato K, Webb S, Zamora M. McMurtry IF, Fisher JH. Increased lung endothelin-1 production in rats with idiopathic pulmonary hypertension. Am J Physiol. 1992;262:L614-L620.
9. Maruyama K, Ye C, Woo M, Venkatacharya H, Lines LD, Silver MM, Rahinovitch M. Chronic hypoxic pulmonary hypertension in rats and increased elastolytic activity. Am J Physiol. 1991;261: H1716-H1726.
10. Todorovich-Hunter L, Dodo H, Ye C, McCready L, Keeley FW, Rabinovitch M. Increased pulmonary artery elastolytic activity in adult rats with monocrotaline-induced progressive hypertensive pulmonary vascular disease compared with infant rats with nonprogressive disease. Am Rev Respir Dis. 1992;146:213-223.
11. Katayose D. Ohe M, Yamauchi K, Ogata M, Shirato K, Fujita H, Shibahara S, Takishima T. Increased expression of PDGF A- and B-chain genes in rat lungs with hypoxic pulmonary hypertension. Am J Physiol. 1993;264:L100-L106.
12. Botney MD, Parks WC, Crouch EC, Stenmark K, Mecham RP. Transforming growth factor-beta is decreased in remodeling hypertensive bovine arteries. J Clin Invest. 1992;89:1629-1635.
13. Perkett EA, Lyons RM, Moses HL, Brigham KL, Meyrick B. Transforming growth factor-beta activity in sheep lung lymph during the development of pulmonary hypertension. J Clin Invest. 1990;86: 1459-1464.
14. Perkett EA, Badesch DB, Roessler MK, Stenmark K, Meyrick B. Insulin-like growth factor I and pulmonary hypertension induced by continuous air embolization in sheep. Am J Respir Cell Mol biol. 1992;6:82-87.
15. Giaid A, Yanagisawa M, Langleben D, Michel RP, Levy R, Shennib H, Kimura S, Masaki T, Duguid W, Path FRC, Stewart DJ. Expression of endothelin-1 in the lungs of patients with pulmonary hypertension. N Engl J Med. 1993;328:1732-1739.
16. Stewart DJ, Levy RD, Cernacek P, Langleben D. Increased plasma endothelin-1 in pulmonary hypertension: marker or mediator of disease? Ann Intern Med. 1991;114:464-469.
17. Yoshibayashi M, Nishioka K, Nakao K, Saito Y, Matsumura M, Ueda T, Temma S, Shirakami G, Imura H, Mikawa H. Plasma endothelin concentrations in patients with pulmonary hypertension associated with congenital heart defects. Circulation. 1991;84: 2280-2285.
18. Rosenberg AA, Kennaugh J, Koppenhafer SL, Loomis M. Elevated immunoreactive endothelin-1 levels in newborn infants with persistent pulmonary hypertension. J Pediatr. 1993;123:109-114.
19. Lemarchand P, Jones M, Yamada I, Crystal RG. In vivo gene transfer and expression in normal, uninjured blood vessels using replication-deficient recombinant adenovirus vectors. Circ Res. 1993;72:1132-1138.
20. Lee SW, Trapnell BC, Rade JJ, Virmani R, Dichek DA. In vivo adenoviral vector-mediated gene transfer into balloon-injured rat carotid arteries. Circ Res. 1993;73:797-807.
21. Rome JJ, Shayani V, Flugelman MY, Newman KD, Fab A, Virmani R, Dichek DA. Anatomic barriers influence the distribution of in vivo gene transfer into the arterial wall: modeling with microscopic tracer particles and verification with a recombinant adenoviral vector. Arterioscler Thromb. 1994;14:148-161.
22. Rome JJ, Shayani V, Newman KD, Farrell S, Lee SW, Virmani R, Dichek DA. Adenoviral vector-mediated gene transfer into sheep arteries using a double balloon catheter. Hum Gene Ther. 1994;5: 1249-1258.
23. Guzman RJ, Lemarchand P, Crystal RG, Epstein SE, Finkel T. Efficient and selective adenovirus-mediated gene transfer into vascular neointima. Circulation. 1993;88:2838-2848.
24. Barr E, Carroll J, Kalynych AM, Tripathy SK, Kozarsky K, Wilson JM, Leiden JM. Efficient catheter-mediated gene transfer into the heart using replication-defective adenovirus. Gene Ther. 1994;1: 51-58.
25. Lemarchand P, Jones M, Danel C, Yamada I, Mastrangeli A, Crystal RG. In vivo adenovirus-mediated gene transfer to lungs via pulmonary artery. J Appl Physiol. 1994;76:2840-2845.
26. Hislop A, Reid L. New findings in pulmonary arteries of rats with hypoxia-induced pulmonary hypertension. Br J Exp Pathol. 1976;57:542-554.
27. Meyrick B, Reid L. Ultrastructural findings in lung biopsy material from children with congenital heart defects. Am J Pathol. 1980;101: 527-542.
28. Pacini DL, Dubovi EJ, Clyde WA. A new animal model for human respiratory tract disease due to adenovirus. J Infect Dis. 1984; 150: 92-97.
29. Prince GA, Portner DD, Jenson AB, Horswood RL, Chanock RM, Ginsberg HS. Pathogenesis of adenovirus type 5 pneumonia in ; cotton rats (Sigmodon hispidus). J Virol. 1993;67:101-111.
30. Mastrangeli A, Danel C, Rosenfeld MA, Stratford-Perricaudet L, Perricaudet M, Pavirani A, Lecocq J-P, Crystal RG. Diversity of airway epithelial cell targets for in vivo recombinant adenovirus-mediated gene transfer. J Clin Invest. 1993;91:225-234.
31. Stinger RB, lacopino VJ, Alter I, Fitzpatrick TM, Rose JC, Kot PA. Catheterization of the pulmonary artery in the closed-chest rat. J Appl Physiol. 1981;51:1047-1050.
32. Weksler B, Ng B, Lenert JT, Burt ME. Isolated single-lung perfusion with doxorubicin is pharmacokinetically superior to intra-venous injection. Ann Thorac Surg. 1993;56:209-214.
33. Smith TAG, Mehaffey MG, Kayda DB, Saunders JM, Yei S, Trapnell BC, McClelland A, Kaleko M. Adenovirus mediated expression of therapeutic plasma levels of human factor IX in mice. Nat Genet. 1993;5:397-402.
34. Sanes JR, Rubenstein JLR, Nicolas JF. Use of a recombinant retrovirus to study post-implantation cell lineage in mouse embryos. EMBO J. 1986;5:3133-3142.
35. Kuhn C. Normal anatomy and histology. In: Thurlbeck WM, ed. Pathology of the Lung. Stuttgart/New York: Thieme Medical Publishers Inc; 1988:11-55.
36. Davidson BL, Doran SE, Shewach DS, Latta JM, Hartman JW, Roessler BJ. Expression of Escherichia coli beta-galactosidase and rat HPRT in the CNS of Macaco mulatto following adenoviral mediated gene transfer. Exp Neural. 1994;125:258-267.
37. Brown KE, Hibbs JR, Gallinella G, Anderson SM, Lehman ED, McCarthy P, Young NS. Resistance to parvovirus B19 infection due to lack of virus receptor (erythrocyte P antigen). N Engl J Med. 1994;330:1192-1196.
38. Rosenfeld MA, Siegfried W, Yoshimura K, Yoneyama K, Fukayama M, Stier LE, Paakko PK, Gilardi P, Stratford-Perricaudet L, Perricaudet M, Jallat S, Pavirani A, Lecocq J-P, Crystal RG. Adenovirus-mediated transfer of a recombinant alpha-1-antitrypsin gene to the lung epithelium in vivo. Science. 1991; 252:431-434.
39. Rosenfeld MA, Yoshimura K, Trapnell BC, Yoneyama K, Rosenthal ER, Dalemans W, Fukayama M, Bargon J, Stier LE, Stratford-Perricaudet L, Perricaudet M, Guggino WB, Pavirani A, Lecocq J-P, Crystal RG. In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium. Cell. 1992;68:143-155.
40. Simon RH, Engelhardt JF, Yang Y, Zepeda M, Weber-Pendleton S, Grossman M, Wilson JM. Adenovirus-mediated gene transfer of the CFTR gene to lungs of nonhuman primates: toxicity study. Hum Gene Ther. 1993;4:771-780.
41. Zabner J, Couture L, Gregory RJ, Graham SM, Smith AE, Welsh MJ. Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis. Cell. 1993;75:207-216.
42. Gehr P, Bachofen M, Weibel ER. The normal human lung: ultrastructure and morphometric estimation of diffusion capacity. Respir Physiol. 1978;32:121-140.
43. Deffebach ME, Widdicombe J. The bronchial circulation. In: Crystal RG, West JB, Barnes PJ, Cherniak NS, Weibel ER, eds. The Lung: Scientific Foundations. New York, NY: Raven Press Publishers; 1991:741-753.
44. deMello D, Reid LM. Arteries and veins. In: Crystal RG, West JB, Barnes PJ, Cherniak NS, Weibel ER, eds. The Lung: Scientific Foundations. New York, NY: Raven Press Publishers; 1991:767-777.
45. Leak LV, Ferrans VJ. Lymphatics and lymphoid tissue. In: Crystal RG, West JB, Barnes PJ, Cherniak NS, Weibel ER, eds. The Lung: Scientific Foundations. New York, NY: Raven Press Publishers; 1991:779-786.
46. Jaffe HA, Longenecker G, Metzger M, Setoguchi Y, Rosenfeld MA, Gant TW, Thorgeirsson SS, Stratford-Perricaudet LD, Perricaudet M, Pavirani A, Lecocq JP, Crystal RC. Adenovirus-mediated in vivo gene transfer and expression in normal rat liver. Nat Genet. 1992;1:372-380.
47. Crystal R, McElvaney NG, Rosenfeld MA, Chu CS, Mastrangeli A, Hay JG, Brody SL, Jaffe HA, Eissa NT, Danel C. Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis. Nat Genet. 1994;8: 42-51.
48. Conary JT, Parker RE, Christman BW, Faulks RD, King GA, Meyrick BO, Brigham KL. Protection of rabbit lungs from endotoxin injury by in vivo hyperexpression of the prostaglandin G/H synthase gene. J Clin Invest. 1994;93:1834-1840.
49. Ginsberg HS, Lundholm-Beauchamp U, Horswood RL, Pernis B, Wold WSM, Chanock RM, Prince GA. Role of early region 3 (E3) in pathogenesis of adenovirus disease. Proc Natl Acad Sci USA. 1989;86:3823-3827.