-
1
-
-
0027029077
-
A fundamental role for cell cycle regulation in the chemosensitivity of cancer cells? Semin
-
O'Connor, P. M., and Kohn, K. W. A fundamental role for cell cycle regulation in the chemosensitivity of cancer cells? Semin. Cancer Biol., 3: 409–416, 1992.
-
(1992)
Cancer Biol.
, vol.3
, pp. 409-416
-
-
O'Connor, P.M.1
Kohn, K.W.2
-
2
-
-
0028870394
-
Genomic instability and the role of p53 mutations in cancer cells
-
Smith, M. L., and Fornace, Jr., A. J. Genomic instability and the role of p53 mutations in cancer cells. Curr. Opin. Oncol., 7: 69–75, 1995.
-
(1995)
Curr. Opin. Oncol.
, vol.7
, pp. 69-75
-
-
Smith, M.L.1
Fornace, A.J.2
-
3
-
-
0024425887
-
Checkpoints: controls that ensure the order of cell cycle events
-
(Washington DC)
-
Hartwell, L. H., and Weinert, T. A. Checkpoints: controls that ensure the order of cell cycle events. Science (Washington DC), 246: 629–634, 1989.
-
(1989)
Science
, vol.246
, pp. 629-634
-
-
Hartwell, L.H.1
Weinert, T.A.2
-
4
-
-
0028568315
-
Cell cycle control and cancer
-
(Washington DC)
-
Hartwell, L. H., and Kastan, M. B. Cell cycle control and cancer. Science (Washington DC), 266: 1821–1825, 1994.
-
(1994)
Science
, vol.266
, pp. 1821-1825
-
-
Hartwell, L.H.1
Kastan, M.B.2
-
5
-
-
0026703325
-
Creative blocks: cell-cycle checkpoints and feedback controls
-
Murray, A. W. Creative blocks: cell-cycle checkpoints and feedback controls. Nature (Lond.), 359: 599–604, 1992.
-
(1992)
Nature (Lond.)
, vol.359
, pp. 599-604
-
-
Murray, A.W.1
-
6
-
-
0026656853
-
Wild-type p53 is a cell cycle checkpoint determinant following irradiation
-
Kuerbitz, S. J., Plunkett, B. S., Walsh, W. V., and Kastan, M. B. Wild-type p53 is a cell cycle checkpoint determinant following irradiation. Proc. Natl. Acad. Sci. USA, 89: 7491–7495, 1992.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 7491-7495
-
-
Kuerbitz, S.J.1
Plunkett, B.S.2
Walsh, W.V.3
Kastan, M.B.4
-
7
-
-
0025894713
-
p53 mutations in human cancers
-
(Washington DC)
-
Hollstein, M., Sidransky, D., Vogelstein, B., and Harris, C. C. p53 mutations in human cancers. Science (Washington DC), 253: 49–52, 1991.
-
(1991)
Science
, vol.253
, pp. 49-52
-
-
Hollstein, M.1
Sidransky, D.2
Vogelstein, B.3
Harris, C.C.4
-
8
-
-
0025876591
-
The p53 tumor suppressor gene
-
Levine, A., Momand, J., and Finlay, C. A. The p53 tumor suppressor gene. Nature (Lond.), 351: 453–456, 1991.
-
(1991)
Nature (Lond.)
, vol.351
, pp. 453-456
-
-
Levine, A.1
Momand, J.2
Finlay, C.A.3
-
9
-
-
0028204160
-
DNA strand breaks: the DNA template alterations that trigger p53 dependent DNA damage response pathways
-
Nelson, W. G., and Kastan, M. B. DNA strand breaks: the DNA template alterations that trigger p53 dependent DNA damage response pathways. Mol. Cell. Biol., 14: 1815–1823, 1994.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 1815-1823
-
-
Nelson, W.G.1
Kastan, M.B.2
-
10
-
-
0028171454
-
p53 gene mutations are associated with decreased sensitivity of human lymphoma cells to DNA damaging agents
-
Fan, S., El-Deiry, W. S., Bae, I., Freeman, J., Jondle, D., Bhatia, K., Fornace, A. J., Jr., Magrath, I., Kohn, K. W., and O'Connor, P. M. p53 gene mutations are associated with decreased sensitivity of human lymphoma cells to DNA damaging agents. Cancer Res., 54: 5824–5830, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 5824-5830
-
-
Fan, S.1
El-Deiry, W.S.2
Bae, I.3
Freeman, J.4
Jondle, D.5
Bhatia, K.6
Fornace, A.J.7
Magrath, I.8
Kohn, K.W.9
O'Connor, P.M.10
-
11
-
-
0027109075
-
p53: guardian of genome
-
Lane, D. P. p53: guardian of genome. Nature (Lond.), 358: 15–16, 1992.
-
(1992)
Nature (Lond.)
, vol.358
, pp. 15-16
-
-
Lane, D.P.1
-
12
-
-
0027319521
-
p53 is required for radiation-induced apoptosis in mouse thymocytes
-
Clarke, A. R., Purdie, C. A., Harrison, D. J., Morris, R. G., Bird, C. C., Hooper, M. L., and Wyllie, A. H. p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature (Lond.), 362: 847–849, 1993.
-
(1993)
Nature (Lond.)
, vol.362
, pp. 847-849
-
-
Clarke, A.R.1
Purdie, C.A.2
Harrison, D.J.3
Morris, R.G.4
Bird, C.C.5
Hooper, M.L.6
Wyllie, A.H.7
-
13
-
-
0027258466
-
Thymocyte apoptosis induced by p53-dependent and independent pathways
-
Lowe, S. W., Schmitt, E. M., Smith, S. W., Osborne, B. A., and Jacks, T. Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature (Lond.), 362: 849–852, 1993.
-
(1993)
Nature (Lond.)
, vol.362
, pp. 849-852
-
-
Lowe, S.W.1
Schmitt, E.M.2
Smith, S.W.3
Osborne, B.A.4
Jacks, T.5
-
14
-
-
0027451668
-
p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
-
Lowe, S. W., Ruley, H. E., Jacks, T., and Houseman, D. E. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell, 74: 957–967, 1993.
-
(1993)
Cell
, vol.74
, pp. 957-967
-
-
Lowe, S.W.1
Ruley, H.E.2
Jacks, T.3
Houseman, D.E.4
-
15
-
-
0028220486
-
Radiation response of mouse lymphoid and myeloid cell lines
-
Apoptotic death is shown by all lines examined
-
Radford, I. R., Murphy, J. M., Radley, J. M., and Ellis, S. L. Radiation response of mouse lymphoid and myeloid cell lines. Part II. Apoptotic death is shown by all lines examined. Int. J. Radiat. Biol., 65: 217–227, 1994.
-
(1994)
Int. J. Radiat. Biol.
, vol.65
, pp. 217-227
-
-
Radford, I.R.1
Murphy, J.M.2
Radley, J.M.3
Ellis, S.L.4
-
16
-
-
0027421045
-
Role of the p53 tumor suppressor gene in cell cycle arrest and radiosensitivity of Burkitt's lymphoma cell lines
-
O'Connor, P., Jackman, J., Jondle, D., Bhatia, K., Magrath, I., and Kohn, K. W. Role of the p53 tumor suppressor gene in cell cycle arrest and radiosensitivity of Burkitt's lymphoma cell lines. Cancer Res., 53: 4776–4780, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 4776-4780
-
-
O'Connor, P.1
Jackman, J.2
Jondle, D.3
Bhatia, K.4
Magrath, I.5
Kohn, K.W.6
-
17
-
-
0027285380
-
p53 mutations increase resistance to ionizing radiation
-
Lee, J. M., and Bernstein, A. p53 mutations increase resistance to ionizing radiation. Proc. Nad. Acad. Sci. USA, 90: 5742–5746, 1993.
-
(1993)
Proc. Nad. Acad. Sci. USA
, vol.90
, pp. 5742-5746
-
-
Lee, J.M.1
Bernstein, A.2
-
18
-
-
0027931008
-
Cell cycle arrests and radiosensitivity of human tumor cell lines: dependence on wild-type p53 for radiosensitivity
-
Mcllwrath, A. J., Vasey, P. A., Ross, G. M., and Brown, R. Cell cycle arrests and radiosensitivity of human tumor cell lines: dependence on wild-type p53 for radiosensitivity. Cancer Res., 54: 3718–3722, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 3718-3722
-
-
Mcllwrath, A.J.1
Vasey, P.A.2
Ross, G.M.3
Brown, R.4
-
19
-
-
0027893001
-
Loss of a p53-associated Gt checkpoint does not decrease cell survival following DNA damage
-
Slichenmyer, W. J., Nelson, W. G., Slebos, R. J., and Kastan, M. B. Loss of a p53-associated Gt checkpoint does not decrease cell survival following DNA damage. Cancer Res., 53: 4164–4168, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 4164-4168
-
-
Slichenmyer, W.J.1
Nelson, W.G.2
Slebos, R.J.3
Kastan, M.B.4
-
20
-
-
0027176479
-
p53 mutation does not correlate with radiosensitivity in head and neck cancer cell lines
-
Brachman, D. G., Beckett, M., Graves, D., Haraf, D., Vokes, E., and Weichselbaum, R. R. p53 mutation does not correlate with radiosensitivity in head and neck cancer cell lines. Cancer Res., 53: 3666–3669, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 3666-3669
-
-
Brachman, D.G.1
Beckett, M.2
Graves, D.3
Haraf, D.4
Vokes, E.5
Weichselbaum, R.R.6
-
21
-
-
0028569767
-
Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen
-
(Washington DC)
-
Smith, M. L., Chen, I., Zhan, Q., Bae, I., Chen, C, Gilmer, T., Kastan, M. B., O'Connor, P. M., and Fornace, A. J., Jr. Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen. Science (Washington DC), 266: 1376–1380, 1994.
-
(1994)
Science
, vol.266
, pp. 1376-1380
-
-
Smith, M.L.1
Chen, I.2
Zhan, Q.3
Bae, I.4
Chen, C.5
Gilmer, T.6
Kastan, M.B.7
O'Connor, P.M.8
Fornace, A.J.9
-
22
-
-
0027944228
-
Induction of bax by genotoxic stress in human cells correlates with normal p53 status and apoptosis
-
Zhan, Q., Fan, S., Bae, I., Guillouf, C, Liebermann, D. A., O'Connor, P. M., and Fornace, A. J., Jr. Induction of bax by genotoxic stress in human cells correlates with normal p53 status and apoptosis. Oncogene, 9: 3743–3751, 1994.
-
(1994)
Oncogene
, vol.9
, pp. 3743-3751
-
-
Zhan, Q.1
Fan, S.2
Bae, I.3
Guillouf, C.4
Liebermann, D.A.5
O'Connor, P.M.6
Fornace, A.J.7
-
23
-
-
0028230596
-
Down-regulation of bcl2 by p53 in breast cancer cells
-
Haldar, S., Negrini, N., Monne, M., Sabbinoni, S., and Croce, C. M. Down-regulation of bcl2 by p53 in breast cancer cells. Cancer Res., 54: 2095–2097, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 2095-2097
-
-
Haldar, S.1
Negrini, N.2
Monne, M.3
Sabbinoni, S.4
Croce, C.M.5
-
24
-
-
0027266971
-
Human papillomavirus 16 E6 expression disrupts the p53-mediated cellular response to DNA damage
-
Kessis, T. D., Slebos, R. J., Nelson, W. G., Kastan, M. B., Plunkett, B. S., Han, S. M., Lorincz, A. T., Hedrick, L., and Cho, K. R. Human papillomavirus 16 E6 expression disrupts the p53-mediated cellular response to DNA damage. Proc. Natl. Acad. Sci. USA, 90: 3988–3992, 1993.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 3988-3992
-
-
Kessis, T.D.1
Slebos, R.J.2
Nelson, W.G.3
Kastan, M.B.4
Plunkett, B.S.5
Han, S.M.6
Lorincz, A.T.7
Hedrick, L.8
Cho, K.R.9
-
25
-
-
0024307545
-
Human nucleotide excision repair in vitro: repair of pyrimidine dimers, psoralen and cisplatin adducts by HeLa cell-free extract
-
Ullah, S., Husain, I., Carlton, W., and Sancar, A. Human nucleotide excision repair in vitro: repair of pyrimidine dimers, psoralen and cisplatin adducts by HeLa cell-free extract. Nucleic Acids Res., 17: 4471–4484, 1989.
-
(1989)
Nucleic Acids Res.
, vol.17
, pp. 4471-4484
-
-
Ullah, S.1
Husain, I.2
Carlton, W.3
Sancar, A.4
-
27
-
-
0028606403
-
Mechanisms of DNA excision repair
-
(Washington DC)
-
Sancar, A. Mechanisms of DNA excision repair. Science (Washington DC), 266: 1954–1956, 1994.
-
(1994)
Science
, vol.266
, pp. 1954-1956
-
-
Sancar, A.1
-
28
-
-
0022590755
-
Cytotoxic, cell cycle and chromosomal effects of methylxanthines in human tumor cells treated with alkylating agents
-
Fingert, H. J., Chang, J. D., and Pardee, A. B. Cytotoxic, cell cycle and chromosomal effects of methylxanthines in human tumor cells treated with alkylating agents. Cancer Res., 46: 2463–2467, 1986.
-
(1986)
Cancer Res.
, vol.46
, pp. 2463-2467
-
-
Fingert, H.J.1
Chang, J.D.2
Pardee, A.B.3
-
29
-
-
0027340012
-
G2 delay induced by nitrogen mustard in human cells affects cyclin A/Cdk2 and cyclin Bl/Cdc2 kinase complexes differently
-
O'Connor, P. M., Ferris, D. K., Pagano, M., Draetta, G., Pines, J., Hunter, T., Longo, D. L., and Kohn, K. W. G2 delay induced by nitrogen mustard in human cells affects cyclin A/Cdk2 and cyclin Bl/Cdc2 kinase complexes differently. J. Biol. Chem., 268: 8298–8308, 1993.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 8298-8308
-
-
O'Connor, P.M.1
Ferris, D.K.2
Pagano, M.3
Draetta, G.4
Pines, J.5
Hunter, T.6
Longo, D.L.7
Kohn, K.W.8
-
30
-
-
0023392945
-
High efficiency transformation of mammalian cells by Plasmid DNA
-
Chen, C, and Okayama, H. High efficiency transformation of mammalian cells by Plasmid DNA. Mol. Cell. Biol., 7: 2745–2752, 1987.
-
(1987)
Mol. Cell. Biol.
, vol.7
, pp. 2745-2752
-
-
Chen, C.1
Okayama, H.2
-
31
-
-
0028919069
-
Involvement of the p53 rumor suppressor in repair of UV-type DNA damage
-
Smith, M. L., Chen, I. T., Zhan, Q., O'Connor, P. M., and Fornace, A. J., Jr. Involvement of the p53 rumor suppressor in repair of UV-type DNA damage. Oncogene, in press, 1995.
-
(1995)
Oncogene
-
-
Smith, M.L.1
Chen, I.T.2
Zhan, Q.3
O'Connor, P.M.4
Fornace, A.J.5
-
32
-
-
84965822602
-
Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay
-
Alley, M. C., Scudieco, D. A., Monks, A., et al Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay. Cancer Res., 48: 589–601, 1988.
-
(1988)
Cancer Res.
, vol.48
, pp. 589-601
-
-
Alley, M.C.1
Scudieco, D.A.2
Monks, A.3
-
33
-
-
0023727057
-
Enhancement of DNA repair capacity of mammalian cells by carcinogen treatment
-
Protic, M., Roilides, E., Levine, A. S., and Dixon, K. Enhancement of DNA repair capacity of mammalian cells by carcinogen treatment. Somat. Cell Mol. Genet, 14: 351–357, 1988.
-
(1988)
Somat. Cell Mol. Genet
, vol.14
, pp. 351-357
-
-
Protic, M.1
Roilides, E.2
Levine, A.S.3
Dixon, K.4
-
34
-
-
0025059372
-
Host-cell reactivation of cisplatin-damaged pRSVcat in a human lymphoid cell line
-
Dabholkar, M., Eastman, A., and Reed, E. Host-cell reactivation of cisplatin-damaged pRSVcat in a human lymphoid cell line. Carcinogenesis (Lond.), 11: 1761–1764, 1990.
-
(1990)
Carcinogenesis (Lond.)
, vol.11
, pp. 1761-1764
-
-
Dabholkar, M.1
Eastman, A.2
Reed, E.3
-
35
-
-
0028607435
-
Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53
-
Scheffher, M., Huibregtse, J. M., and Howley, P. M. Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53. Proc. Natl. Acad. Sci. USA, 91: 8797–8801, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 8797-8801
-
-
Scheffher, M.1
Huibregtse, J.M.2
Howley, P.M.3
-
36
-
-
0027369120
-
Increased accumulation of p53 protein in cisplatin-resistant ovarian cell lines
-
Brown, R., Clugston, C, Burns, P., Edlin, A., Vasey, P., Vojtesek, B., and Kaye, S. Increased accumulation of p53 protein in cisplatin-resistant ovarian cell lines. Int. J. Cancer, 55: 678–684, 1993.
-
(1993)
Int. J. Cancer
, vol.55
, pp. 678-684
-
-
Brown, R.1
Clugston, C.2
Burns, P.3
Edlin, A.4
Vasey, P.5
Vojtesek, B.6
Kaye, S.7
-
37
-
-
0027970713
-
DNA damage triggers a prolonged p53-dependent Gt arrest and long-term induction of Cipl in normal human fibroblasts
-
Di Leonardo, A., Linke, S. P., Clarkin, K., and Wahl, G. M. DNA damage triggers a prolonged p53-dependent Gt arrest and long-term induction of Cipl in normal human fibroblasts. Genes Dev., 8: 2540–2551, 1994.
-
(1994)
Genes Dev.
, vol.8
, pp. 2540-2551
-
-
Leonardo, A.1
Linke, S.P.2
Clarkin, K.3
Wahl, G.M.4
-
38
-
-
0001655748
-
Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3
-
Wang, X. W., Forrester, K., Yeh, H., Feitelson, M. A., Gu, J. R., and Harris, C. C Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3. Proc. Natl. Acad. Sci. USA, 91: 2230–2234, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 2230-2234
-
-
Wang, X.W.1
Forrester, K.2
Yeh, H.3
Feitelson, M.A.4
Gu, J.R.5
Harris, C.6
-
39
-
-
0028936626
-
Differential sensitivity of p53- and p53+ cells to caffeine-induced radiosensitization and override of G2 delay
-
Powell, S. N., DeFrank, J. S., Connell, P., Eogan, M., Preffer, F., Dombkowski, D., Tang, W., and Friend, S. Differential sensitivity of p53- and p53+ cells to caffeine-induced radiosensitization and override of G2 delay. Cancer Res., 55: 1643–1648, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 1643-1648
-
-
Powell, S.N.1
DeFrank, J.S.2
Connell, P.3
Eogan, M.4
Preffer, F.5
Dombkowski, D.6
Tang, W.7
Friend, S.8
-
40
-
-
0028985932
-
Abrogation of the G2 checkpoint results in differential radiosensitization of Gj checkpoint-deficient and competent cells
-
Russell, K. J., Wiens, L. W., Galloway, D. A., and Groudine, M. Abrogation of the G2 checkpoint results in differential radiosensitization of Gj checkpoint-deficient and competent cells. Cancer Res., 55: 1639–1642, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 1639-1642
-
-
Russell, K.J.1
Wiens, L.W.2
Galloway, D.A.3
Groudine, M.4
-
41
-
-
0028071123
-
Role of the cdc25C phosphatase in G2 arrest induced by nitrogen mustard
-
O'Connor, P. M., Ferris, D. K., Hoffmann, I., Jackman, J., Draetta, G., and Kohn, K. W. Role of the cdc25C phosphatase in G2 arrest induced by nitrogen mustard. Proc. Natl. Acad. Sci. USA, 91: 9480–9484, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9480-9484
-
-
O'Connor, P.M.1
Ferris, D.K.2
Hoffmann, I.3
Jackman, J.4
Draetta, G.5
Kohn, K.W.6
-
42
-
-
0023803098
-
In vivo and in vitro enhanced antitumor effects by pentoxifylline in human cancer cells treated with thiotepa
-
Fingert, H. J., Pu, A. T., Chen, Z., Googe, P. B., Alley, M. C., and Pardee, A. B. In vivo and in vitro enhanced antitumor effects by pentoxifylline in human cancer cells treated with thiotepa. Cancer Res., 48: 4375–4381, 1988.
-
(1988)
Cancer Res.
, vol.48
, pp. 4375-4381
-
-
Fingert, H.J.1
Pu, A.T.2
Chen, Z.3
Googe, P.B.4
Alley, M.C.5
Pardee, A.B.6
-
43
-
-
0002162281
-
Drugs used in the treatment of asthma
-
New York: Pergamon Press
-
Rail, T. W. Drugs used in the treatment of asthma. In: A. G. Gilman, T. W. Rail, A. S. Nies, and P. Taylor (eds.), Goodman and Gilman's Pharmacological Basis of Therapeutics, Ed. 8, pp. 618–637. New York: Pergamon Press, 1985.
-
(1985)
Goodman and Gilman's Pharmacological Basis of Therapeutics
, vol.8
, pp. 618-637
-
-
Rail, T.W.1
|