CJ-12,371 and CJ-12,372, Two Novel DNA Gyrase Inhibitors Fermentation, Isolation, Structural Elucidation and Biological Activities

The Journal of Antibiotics

Volumn 48, Issue 2, 1995, Pages 134-142

  Norcia, Michael ^a   Wondrack, Lillian M ^a   Sutcliffe, Joyce A ^a   Hirai, Hideo ^a   Iwata, Etsuko ^a   Sakakibara, Tatsuo ^a   Yamauchi, Yuji ^a   Kojima, Nakao ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CIPROFLOXACIN; CJ 12371; CJ 12372; DNA TOPOISOMERASE; DOUBLE STRANDED DNA; GYRASE INHIBITOR; NOVOBIOCIN; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DNA SUPERCOILING; DRUG ISOLATION; DRUG MECHANISM; DRUG POTENCY; DRUG PURIFICATION; DRUG SELECTIVITY; DRUG STRUCTURE; ENZYME INHIBITION; EUKARYOTIC CELL; FUNGUS; GRAM POSITIVE BACTERIUM; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; REVERSED PHASE LIQUID CHROMATOGRAPHY; STEREOCHEMISTRY;

ANTIBIOTICS; DNA TOPOISOMERASES, TYPE II; ESCHERICHIA COLI; FERMENTATION; FUNGI; GRAM-POSITIVE BACTERIA; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; NAPHTHALENES; SPECTRUM ANALYSIS; STEREOISOMERISM;

EID: 0028899173     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.7164/antibiotics.48.134     Document Type: Article

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