The membrane distal half of gp130 is responsible for the formation of a ternary complex with IL-6 and the IL-6 receptor

FEBS Letters

Volumn 360, Issue 1, 1995, Pages 43-46

  Horsten, Ursula ^a   Schmitz Van de Leur, Hildegard ^a   Müllberg, Jürgen ^c   Heinrich, Peter C ^a   Rose John, Stefan ^b  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^c AMGEN INC   (United States)

Author keywords

Cytokine receptor domain; gp130; Interleukin 6; Structure function analysis

Indexed keywords

GLYCOPROTEIN GP 130; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; INTERLEUKIN RECEPTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DELETION MUTANT; DRUG RECEPTOR BINDING; GENE EXPRESSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; STRUCTURE ACTIVITY RELATION;

ANIMAL; BASE SEQUENCE; CELL LINE; HAPLORHINI; INTERLEUKIN-6; MEMBRANE GLYCOPROTEINS; MOLECULAR SEQUENCE DATA; OLIGODEOXYRIBONUCLEOTIDES; PROTEIN BINDING; RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-6; SIGNAL TRANSDUCTION;

EID: 0028897161     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-5793(95)00053-C     Document Type: Article

References (29)

1. Functional inhibition of hematopoietic and neurotrophic cytokines by blocking the interleukin 6 signal transducer gp130.
2. Interactions between oncostatin M and the IL-6 signal transducer, gp130