Nerve growth factor and neurotrophin-3 enhance neurite outgrowth and up-regulate the levels of messenger RNA for growth-associated protein GAP-43 and Tα1 α-tubulin in cultured adult rat sensory neurones

Neuroscience Letters

Volumn 185, Issue 1, 1995, Pages 20-23

  Mohiuddin, L ^a   Fernandez, K ^a   Tomlinson, D R ^a   Fernyhough, P ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Axonal outgrowth; Culture; Cytoskeletal proteins; mRNA expression; Neurotrophin; Regeneration; Sensory neurones

Indexed keywords

ALPHA TUBULIN; MESSENGER RNA; NERVE GROWTH FACTOR; NEUROMODULIN; NEUROTROPHIN 3;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONTROLLED STUDY; MALE; NEURITE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RAT; SENSORY NERVE; SPINAL GANGLION;

ANIMAL; BLOTTING, NORTHERN; CELL DIVISION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; GAP-43 PROTEIN; MALE; MEMBRANE GLYCOPROTEINS; NERVE GROWTH FACTORS; NERVE TISSUE PROTEINS; NEURONS; NEURONS, AFFERENT; RATS; RATS, WISTAR; RNA, MESSENGER; SUPPORT, NON-U.S. GOV'T; UP-REGULATION;

EID: 0028896671     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3940(94)11215-5     Document Type: Article

References (22)

1. Primary structure and transcriptional regulation of GAP-43, a protein associated with nerve growth
2. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
3. Sensory nerves in adult rats regenerate and restore sensory function to the skin independently of endogenous NGF
4. The neurotrophins BDNF, NT-3, and NGF display distinct patterns of retrograde axonal transport in peripheral and central neurons
5. Dual regulation of GAP-43 gene expression by nerve growth factor and glucocorticoids
6. Nerve growth factor modulates tubulin transcript levels in pheochromocytoma PC12 cells
7. Insulin and insulin-like growth factor I enhance regeneration in cultured adult rat sensory neurones
8. Neurotrophins promote motor neuron survival and are present in embryonic limb bud
9. Neurotrophin 3 supports the survival of developing muscle sensory neurons in culture
10. Evidence that brain-derived neurotrophic factor is a trophic factor for motor neurons in vivo
11. Nerve growth factors (NGF BDNF) enhance axonal regeneration but are not required for survival of adult sensory neurons
12. Nerve growth factor regulates expression of neuropeptide genes in adult sensory neurons
13. Nerve growth factor regulates expression of the nerve growth factor receptor gene in adult sensory neurons
14. Neurotrophin-3: a neurotrophic factor related to NGF and BDNF
15. Expression and coexpression of trk receptors in subpopulations of adult primary sensory neurons projecting to identified peripheral targets
16. Isotypes of α-tubulin are differentially regulated during neuronal maturation
17. Nerve growth factor enhances regeneration through silicone chambers
18. Functions of the neurotrophins during nervous system development: what the knockouts are teaching us
19. Colocalization of NGF binding sites, trk mRNA, and low-affinity NGF receptor mRNA in primary sensory neurons: responses to injury and infusion of NGF
20. Influence of nerve growth factor on neurofilament gene expression in mature primary sensory neurons
21. NGF rescues substance P expression but not neurofilament or tubulin gene expression in axotomized sensory neurons
22. The neurotrophins BDNF, NT-3 and NT-4/5, but not NGF, up-regulate the cholinergic phenotype of developing motor neurons