The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy

Cell

Volumn 80, Issue 1, 1995, Pages 167-178

  Roy, Natalie ^a,b   Mahadevan, Mani S ^a   McLean, Michael ^a,b   Shutter, Gary ^a   Yaraghi, Zahra ^a,b   Farahani, Reza ^a,b   Baird, Stephen ^a   Besner Johnston, Anne ^a   Lefebvre, Charles ^a,b   Kang, Xiaolin ^a,b   Salih, Maysoon ^b   Aubry, Huguette ^a   Tamai, Katsuyuki ^b   Guan, Xiaoping ^c   Ioannou, Panayiotis ^c   Crawford, Thomas O ^d   de Jong, Pieter J ^c   Surh, Linda ^a   Ikeda, Joh E ^b,e   Korneluk, Robert G ^a,b   MacKenzie, Alex ^a,b   more..

^a CHILDREN S HOSPITAL OF EASTERN ONTARIO   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

^c ROSWELL PARK CANCER INSTITUTE   (United States)

^d JOHNS HOPKINS UNIVERSITY   (United States)

^e TOKAI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; ARTICLE; GENE DELETION; GENE LOCUS; GENE MAPPING; GENETIC LINKAGE; HUMAN; MOTONEURON; PATHOGENESIS; PRIORITY JOURNAL; SPINAL MUSCULAR ATROPHY;

EID: 0028896092     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(95)90461-1     Document Type: Article

References (53)

1. Basic alignment search tool
2. PROSITE: recent developments
3. An apoptosisinhibiting gene from a nuclear polyhedrosis virus encoding a polypeptide with Cys-His sequence motifs
4. Mapping of two new markers within the smallest interval harboring the spinal muscular atrophy locus by family and radiation hybrid analysis
5. Genetic mapping of chronic childhood-onset spinal muscular atrophy to chromosome 5q1.2-13.3
6. Fine-mapping of the spinal muscular atrophy locus to a region flanked by MAP1 B and D5S6
7. Linkage mapping of the spinal muscular atrophy gene
8. A multicopy dinucleotide marker that maps close to the spinal muscular atrophy gene
9. Ordered shotgun sequencing: a strategy for integrated mapping and sequencing of YAC clones
10. Isolation of genes from complex sources of mammalian genomic DNA using exon amplification
11. Apoptosis reduces both the in vitro replication and the in vivo infectivity of a baculovirus
12. Induction and inhibition of apoptosis by insect viruses
13. Control of programmed cell death by the baculovirus genes p35 and IAP
14. Use of genetic and physical mapping to locate the spinal muscular atrophy locus between two new highly polymorphic DNA markers
15. A de novo pathological point mutation at the 21-hydroxylase locus: implications for gene conversion in the human genome
16. An apoptosisinhibiting baculovirus gene with a zinc finger-like motif
17. A sequence assembly and editing program for efficient management of large projects
18. Association between Ag1-CA alleles and severity of autosomal recessive proximal spinal muscular atrophy
19. Population frequencies of inherited neuromuscular diseases: a world survey
20. Genes for the a and y subunits of mouse nerve growth factor are contiguous
21. A contig of non-chimeric YACs containing the spinal muscular atrophygene in 5q13
22. Occludin: a novel integral membrane protein localizing at tight junctions
23. Deletion mapping of DNA markers to a region of chromosome 5 that cosegregates with schizophrenia
24. Genetic homogeneity between acute and chronic forms of spinal muscular atrophy
25. n repeats
26. A trace display and editing program for data from fluorescence based sequencing machines
27. Gametic disequilibrium measures: proceed with caution
28. Isolation and chromosomal assignment of 100 highly informative human simple sequence repeat polymorphisms
29. A new bacteriophage P1-derived vector for the propagation of large human DNA fragments
30. A model recognition approach to the prediction of all-helical membrane protein structure and topology
31. Construction of a yeast artificial chromosome contig spanning the spinal muscular atrophy disease gene region
32. Identification and characterization of a spinal muscular atrophy-determining gene
33. Mapping of human microtubule associated protein 1B in proximity to the spinal muscular atrophy locus at 5q13.1
34. Genetic linkage analysis of Canadian spinal muscular atrophy kindreds using flanking microsatellite 5q13 polymorphisms
35. Two 5q13 simple tandem repeat loci are in linkage disequilibrium with type I spinal muscular atrophy
36. Gene for chronic proximal spinal muscular atrophies maps to chromosome 5q
37. De novo and inherited deletions of the 5q13 region in spinal muscular atrophies
38. Immunocytochemical and ultrastructural studies of Werdnig-Hoffmann disease
39. Cell death during development of the nervous system
40. “Chromatolytic” neurons in lateral geniculate body in Werdnig-Hoffmann disease
41. An empiric comparison of linkage disequilibrium parameters in disease gene localization: the myotonic dystrophy experience
42. Refined physical map of the spinal muscular atrophy gene region at 5q13 based on YAC and cosmid contiguous arrays
43. Histopathology of SMA
44. Linkage analysis in spinal muscular atrophy, by six closely flanking markers on chromosome 5
45. Refinement of the spinal muscular atrophy locus to the interval between D5S435 and MAP1B
46. High resolution physical map of the region surrounding the spinal muscular atrophy gene
47. Is Werdnig-Hoffmann disease a pure lower motor neuron disorder?
48. Steroid 21-hydroxylase (P450c21): a new allele and spread of mutations through the pseudogene
49. Fine mapping and narrowing of the genetic interval of the spinal muscular atrophy region by linkage studies
50. Large linkage analysis in 100 families with autosomal recessive spinal muscular atropy (SMA) and 11 CEPH families using 13 polymorphic loci in the region 5q11.2-q13.3